Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MHHHKEFG_RS05555 Genome accession   NZ_CP069125
Coordinates   1141511..1142176 (+) Length   221 a.a.
NCBI ID   WP_012009573.1    Uniprot ID   -
Organism   Bacillus pumilus strain D5     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1136511..1147176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MHHHKEFG_RS05520 (MHHHKEFG_01122) - 1136845..1137924 (+) 1080 WP_034663262.1 ABC transporter ATP-binding protein -
  MHHHKEFG_RS05525 (MHHHKEFG_01123) - 1137926..1138846 (+) 921 WP_034663259.1 ABC transporter ATP-binding protein -
  MHHHKEFG_RS05530 (MHHHKEFG_01124) - 1138952..1139239 (+) 288 WP_060596004.1 hypothetical protein -
  MHHHKEFG_RS05535 (MHHHKEFG_01125) - 1139376..1139954 (+) 579 WP_060596005.1 GNAT family N-acetyltransferase -
  MHHHKEFG_RS05540 (MHHHKEFG_01126) spxA 1140148..1140543 (+) 396 WP_003211421.1 transcriptional regulator SpxA -
  MHHHKEFG_RS05545 (MHHHKEFG_01127) - 1140583..1141248 (-) 666 WP_060596006.1 TerC family protein -
  MHHHKEFG_RS05550 - 1141424..1141544 (+) 121 Protein_1036 hypothetical protein -
  MHHHKEFG_RS05555 (MHHHKEFG_01128) mecA 1141511..1142176 (+) 666 WP_012009573.1 adaptor protein MecA Regulator
  MHHHKEFG_RS05560 (MHHHKEFG_01129) cls 1142262..1143782 (+) 1521 WP_034663247.1 cardiolipin synthase -
  MHHHKEFG_RS05565 (MHHHKEFG_01130) - 1143944..1145104 (+) 1161 WP_066031038.1 competence protein CoiA -
  MHHHKEFG_RS05570 (MHHHKEFG_01131) pepF 1145319..1147145 (+) 1827 WP_282959022.1 oligoendopeptidase F -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 26405.18 Da        Isoelectric Point: 3.9851

>NTDB_id=532375 MHHHKEFG_RS05555 WP_012009573.1 1141511..1142176(+) (mecA) [Bacillus pumilus strain D5]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIVVTKAQL
SKDGQKLELPIPEDKKDQTDEESLDALLDDFQKEEQDQEDHNEKDKKLQLQFVLKMDDFEDLIALSQLNMQDFTTSLYSF
ENRYYLYVDFHEDLSDEQVENKLSILLEYAHESVVSIYRLKEYGQLIIEGNALETIQQHFS

Nucleotide


Download         Length: 666 bp        

>NTDB_id=532375 MHHHKEFG_RS05555 WP_012009573.1 1141511..1142176(+) (mecA) [Bacillus pumilus strain D5]
ATGGAAATCGAAAGAATTAATGAACATACAGTGAAATTTTATATTTCCTACGGTGATATTGAAGACCGCGGATTTGACCG
TGAAGAAATTTGGTATAATCGTGAACGCAGTGAAGAGCTGTTTTGGGAAGTAATGGACGAAGTGCACGAAGAAGAAGAAT
TTGCAGTTGAGGGACCTCTTTGGATTCAAGTGCAGGCACTTGACAAAGGTCTTGAAATTGTCGTGACGAAAGCCCAACTT
TCTAAAGATGGACAAAAGCTCGAATTGCCGATTCCAGAAGATAAAAAAGATCAAACAGATGAAGAAAGTCTAGACGCACT
GCTTGATGATTTTCAAAAAGAAGAGCAGGATCAAGAAGACCATAATGAGAAGGACAAAAAACTTCAACTTCAATTTGTGT
TGAAAATGGATGACTTTGAAGATTTGATTGCACTTTCTCAATTAAATATGCAGGATTTTACCACAAGTTTATATTCGTTT
GAAAACCGTTATTATCTATATGTTGACTTCCACGAGGATTTGTCAGATGAGCAAGTGGAGAATAAGCTCAGCATTTTGCT
TGAATATGCTCATGAATCAGTGGTCAGCATTTACAGACTGAAAGAATACGGTCAGCTGATTATCGAAGGAAATGCCCTTG
AAACGATTCAACAGCACTTCTCGTAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

77.376

100

0.774