Detailed information NTG0053228

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: C248_RS13450
• Genome accession: NC_018608
• Coordinates: 2677801..2678688 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus 08BA02176
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2672801..2683688

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C248_RS13415	-	2672811..2672903 (+)	93	WP_031774855.1	hypothetical protein	-
C248_RS13420 (C248_2685)	-	2673011..2673508 (-)	498	WP_001065267.1	glutathione peroxidase	-
C248_RS13425 (C248_2686)	-	2673518..2673778 (-)	261	WP_014937088.1	hypothetical protein	-
C248_RS13430 (C248_2688)	-	2674160..2674273 (-)	114	WP_014937089.1	hypothetical protein	-
C248_RS13440 (C248_2689)	-	2674942..2676942 (-)	2001	WP_000776741.1	ABC transporter permease	-
C248_RS13445 (C248_2690)	-	2676939..2677694 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
C248_RS13450 (C248_2691)	braS	2677801..2678688 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
C248_RS13455 (C248_2692)	braR	2678699..2679364 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
C248_RS13460 (C248_2693)	-	2679390..2679590 (-)	201	WP_000604731.1	hypothetical protein	-
C248_RS13470 (C248_2694)	-	2679788..2681212 (+)	1425	WP_000953736.1	alkaline phosphatase	-
C248_RS14910 (C248_2695)	-	2681283..2681393 (+)	111	WP_001791296.1	hypothetical protein	-
C248_RS13475 (C248_2696)	-	2681496..2681951 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
C248_RS13480 (C248_2697)	-	2682195..2682956 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=53228 C248_RS13450 WP_000143420.1 2677801..2678688(-) (braS) [Staphylococcus aureus 08BA02176]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=53228 C248_RS13450 WP_000143420.1 2677801..2678688(-) (braS) [Staphylococcus aureus 08BA02176]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993