Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   LLUC047_RS12455 Genome accession   NZ_CP068658
Coordinates   2389309..2390340 (-) Length   343 a.a.
NCBI ID   WP_021216375.1    Uniprot ID   -
Organism   Lactococcus cremoris strain UC047     
Function   processing of CSP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2380994..2397764 2389309..2390340 within 0
IS/Tn 2387598..2388488 2389309..2390340 flank 821


Gene organization within MGE regions


Location: 2380994..2397764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC047_RS12420 (LLUC047_12130) - 2381757..2382782 (+) 1026 WP_011677208.1 lactonase family protein -
  LLUC047_RS12425 (LLUC047_12135) adhE 2383037..2385748 (+) 2712 WP_015082945.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase -
  LLUC047_RS12430 (LLUC047_12140) - 2386212..2386709 (-) 498 WP_011677211.1 nitroreductase family protein -
  LLUC047_RS12435 (LLUC047_12145) - 2386732..2386911 (-) 180 WP_050574404.1 hypothetical protein -
  LLUC047_RS12440 (LLUC047_12150) - 2387199..2388089 (+) 891 WP_014572485.1 IS982-like element IS982B family transposase -
  LLUC047_RS12445 (LLUC047_12155) - 2388090..2388809 (-) 720 WP_021216373.1 radical SAM protein -
  LLUC047_RS12450 (LLUC047_12160) - 2388877..2388990 (-) 114 WP_021216374.1 KxxxW-cyclized peptide pheromone -
  LLUC047_RS12455 (LLUC047_12165) sepM 2389309..2390340 (-) 1032 WP_021216375.1 SepM family pheromone-processing serine protease Regulator
  LLUC047_RS12460 (LLUC047_12170) coaD 2390324..2390824 (-) 501 WP_011677214.1 pantetheine-phosphate adenylyltransferase -
  LLUC047_RS12465 (LLUC047_12175) rsmD 2390872..2391411 (-) 540 WP_031286167.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  LLUC047_RS12470 (LLUC047_12180) - 2391582..2392802 (-) 1221 WP_011677216.1 MFS transporter -
  LLUC047_RS12475 (LLUC047_12185) lmrP 2392886..2394112 (-) 1227 Protein_2425 multidrug efflux MFS transporter LmrP -
  LLUC047_RS12480 (LLUC047_12190) - 2394300..2394794 (+) 495 WP_021211251.1 RNA polymerase sigma factor -
  LLUC047_RS12485 (LLUC047_12195) - 2394818..2395924 (+) 1107 WP_354666086.1 anti-sigma factor -
  LLUC047_RS12490 (LLUC047_12200) - 2396019..2397365 (-) 1347 WP_021211249.1 glucose-6-phosphate isomerase -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 37428.05 Da        Isoelectric Point: 9.8499

>NTDB_id=530285 LLUC047_RS12455 WP_021216375.1 2389309..2390340(-) (sepM) [Lactococcus cremoris strain UC047]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGSREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=530285 LLUC047_RS12455 WP_021216375.1 2389309..2390340(-) (sepM) [Lactococcus cremoris strain UC047]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTAGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(229-339)

PDZ domain (PDZ_2)

(135-193)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.406

100

0.487