Detailed information NTG0529463

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: K8B68_RS12560
• Genome accession: NZ_CP082813
• Coordinates: 2549570..2551678 (+)
• Length: 702 a.a.
• NCBI ID: WP_001063338.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain SCAID OTT1-2021 (597/2)
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2544570..2556678

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K8B68_RS12535 (K8B68_12535)	-	2544637..2544855 (+)	219	WP_223081684.1	sterile alpha motif-like domain-containing protein	-
K8B68_RS12540 (K8B68_12540)	-	2545243..2545674 (+)	432	WP_000875614.1	CHAP domain-containing protein	-
K8B68_RS12545 (K8B68_12545)	-	2545814..2547094 (-)	1281	WP_001191002.1	hydroxymethylglutaryl-CoA reductase, degradative	-
K8B68_RS12550 (K8B68_12550)	-	2547349..2548515 (+)	1167	WP_000151984.1	hydroxymethylglutaryl-CoA synthase	-
K8B68_RS12555 (K8B68_12555)	-	2548686..2549207 (-)	522	WP_000262599.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
K8B68_RS12560 (K8B68_12560)	clpE	2549570..2551678 (+)	2109	WP_001063338.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
K8B68_RS12565 (K8B68_12565)	-	2551745..2551915 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
K8B68_RS12570 (K8B68_12570)	feoB	2551928..2553922 (-)	1995	WP_000432903.1	ferrous iron transport protein B	-
K8B68_RS12575 (K8B68_12575)	-	2553934..2554161 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78430.85 Da
• Isoelectric Point: 4.6237

>NTDB_id=529463 K8B68_RS12560 WP_001063338.1 2549570..2551678(+) (clpE) [Staphylococcus aureus strain SCAID OTT1-2021 (597/2)]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELSQFTQQDDNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDRLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFETHHQVKLPNDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIVICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRNKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=529463 K8B68_RS12560 WP_001063338.1 2549570..2551678(+) (clpE) [Staphylococcus aureus strain SCAID OTT1-2021 (597/2)]
ATGAATAACAATTTTTTCAATAGTGATTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTATCACAATTTACGCAACAAGATGATAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACAGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAATGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCTCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGAATTCGTGAAAAATTTGAAACACACCATCAAGTCAAATTACCTAATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCCTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCAGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATCGGTCAAGACCA
AGCTGTAGAGATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGATTCGATGACGGCAACCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTTCAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCGTTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGTCCTGAATTCCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AATCACTTCAAGAAATCATTAATTTATTGTTGGATGATGTCCAAGTAACACTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAGTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTAACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA lid domain (AAA_lid_9) (264-363)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.589	91.595	0.436
clpC	Lactococcus lactis subsp. cremoris KW2	44.279	95.869	0.424
clpE	Streptococcus pneumoniae Rx1	47.002	87.892	0.413
clpE	Streptococcus pneumoniae D39	47.002	87.892	0.413
clpE	Streptococcus pneumoniae R6	47.002	87.892	0.413
clpE	Streptococcus pneumoniae TIGR4	47.002	87.892	0.413
clpC	Bacillus subtilis subsp. subtilis str. 168	44.325	92.877	0.412
clpC	Streptococcus thermophilus LMD-9	44	89.031	0.392
clpC	Streptococcus thermophilus LMG 18311	43.68	89.031	0.389
clpC	Streptococcus pneumoniae TIGR4	42.652	89.174	0.38
clpC	Streptococcus pneumoniae Rx1	42.652	89.174	0.38
clpC	Streptococcus pneumoniae D39	42.652	89.174	0.38
clpC	Streptococcus mutans UA159	43.089	87.607	0.377
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.573	88.746	0.369