Detailed information NTG0529374

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: K3B00_RS13625
• Genome accession: NZ_CP082789
• Coordinates: 2700136..2702241 (+)
• Length: 701 a.a.
• NCBI ID: WP_070997609.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain HL24830
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2695136..2707241

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K3B00_RS13600 (K3B00_002709)	-	2695158..2695376 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
K3B00_RS13605 (K3B00_002710)	-	2695766..2696197 (+)	432	WP_000455861.1	CHAP domain-containing protein	-
K3B00_RS13610 (K3B00_002711)	-	2696335..2697615 (-)	1281	WP_001180324.1	hydroxymethylglutaryl-CoA reductase, degradative	-
K3B00_RS13615 (K3B00_002712)	-	2697869..2699035 (+)	1167	WP_000151983.1	hydroxymethylglutaryl-CoA synthase	-
K3B00_RS13620 (K3B00_002713)	-	2699206..2699727 (-)	522	WP_000455992.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
K3B00_RS13625 (K3B00_002714)	clpE	2700136..2702241 (+)	2106	WP_070997609.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
K3B00_RS13630 (K3B00_002715)	-	2702310..2702480 (-)	171	WP_000111118.1	FeoB-associated Cys-rich membrane protein	-
K3B00_RS13635 (K3B00_002716)	feoB	2702493..2704487 (-)	1995	WP_000432934.1	ferrous iron transport protein B	-
K3B00_RS13640 (K3B00_002717)	-	2704499..2704726 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77824.16 Da
• Isoelectric Point: 4.6056

>NTDB_id=529374 K3B00_RS13625 WP_070997609.1 2700136..2702241(+) (clpE) [Staphylococcus aureus strain HL24830]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAATKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2106 bp

>NTDB_id=529374 K3B00_RS13625 WP_070997609.1 2700136..2702241(+) (clpE) [Staphylococcus aureus strain HL24830]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTCCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTCTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAACCAAAGACAAAGAAATTATTTCTGTA
GATATTTCATCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACGCTGAAGAAAAAGATATTAT
GCACGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTGCAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGCTATGATGAAGAATTAGGTGCACGTCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTATTATCTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA lid domain (AAA_lid_9) (264-363)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.834	91.726	0.448
clpE	Streptococcus pneumoniae Rx1	48.298	88.017	0.425
clpE	Streptococcus pneumoniae D39	48.298	88.017	0.425
clpE	Streptococcus pneumoniae R6	48.298	88.017	0.425
clpE	Streptococcus pneumoniae TIGR4	48.298	88.017	0.425
clpC	Lactococcus lactis subsp. cremoris KW2	46.815	89.586	0.419
clpC	Bacillus subtilis subsp. subtilis str. 168	44.564	93.153	0.415
clpC	Streptococcus thermophilus LMD-9	44.392	90.3	0.401
clpC	Streptococcus thermophilus LMG 18311	44.076	90.3	0.398
clpC	Streptococcus pneumoniae TIGR4	44.175	88.16	0.389
clpC	Streptococcus pneumoniae Rx1	44.175	88.16	0.389
clpC	Streptococcus pneumoniae D39	44.175	88.16	0.389
clpC	Streptococcus mutans UA159	43.577	87.732	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.294	92.582	0.382