Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | LLF72_RS02880 | Genome accession | NZ_CP068511 |
| Coordinates | 555432..557678 (+) | Length | 748 a.a. |
| NCBI ID | WP_015082116.1 | Uniprot ID | - |
| Organism | Lactococcus cremoris strain F.2.7 | ||
| Function | degradation of ComX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 557369..595611 | 555432..557678 | flank | -309 |
Gene organization within MGE regions
Location: 555432..595611
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LLF72_RS02880 (LLF72_02810) | clpC | 555432..557678 (+) | 2247 | WP_015082116.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| LLF72_RS02885 (LLF72_02815) | - | 557804..558274 (-) | 471 | WP_015082117.1 | Rrf2 family transcriptional regulator | - |
| LLF72_RS02890 (LLF72_02820) | gap | 558500..559513 (+) | 1014 | Protein_542 | type I glyceraldehyde-3-phosphate dehydrogenase | - |
| LLF72_RS02895 (LLF72_02825) | def | 559737..560372 (-) | 636 | WP_011675571.1 | peptide deformylase | - |
| LLF72_RS02900 (LLF72_02830) | - | 560527..560931 (+) | 405 | WP_015082118.1 | RNA pyrophosphohydrolase | - |
| LLF72_RS02905 (LLF72_02835) | uvrB | 560993..563071 (+) | 2079 | WP_011675573.1 | excinuclease ABC subunit UvrB | - |
| LLF72_RS02910 (LLF72_02840) | - | 563280..563729 (+) | 450 | WP_237025406.1 | transporter substrate-binding domain-containing protein | - |
| LLF72_RS02920 (LLF72_02850) | - | 565196..565561 (+) | 366 | WP_021213719.1 | transporter substrate-binding domain-containing protein | - |
| LLF72_RS02925 (LLF72_12855) | - | 565576..566115 (+) | 540 | WP_228763946.1 | M20 family metallopeptidase | - |
| LLF72_RS02930 (LLF72_12860) | - | 566112..566342 (+) | 231 | Protein_550 | peptidase dimerization domain-containing protein | - |
| LLF72_RS02935 (LLF72_12865) | - | 566561..566695 (+) | 135 | WP_231097943.1 | hypothetical protein | - |
| LLF72_RS02940 (LLF72_02860) | fabZ | 566747..567202 (-) | 456 | WP_011675575.1 | 3-hydroxyacyl-ACP dehydratase FabZ | - |
| LLF72_RS02945 (LLF72_02865) | fabI | 567478..568230 (+) | 753 | WP_015082121.1 | enoyl-ACP reductase FabI | - |
| LLF72_RS02950 (LLF72_02870) | yidC | 568416..569378 (-) | 963 | WP_015082122.1 | membrane protein insertase YidC | - |
| LLF72_RS02955 (LLF72_02875) | - | 569553..570311 (-) | 759 | WP_011675578.1 | HAD-IIB family hydrolase | - |
| LLF72_RS02960 (LLF72_02880) | - | 570406..570996 (-) | 591 | WP_011675579.1 | ECF transporter S component | - |
| LLF72_RS02965 (LLF72_02885) | coaC | 571013..571549 (-) | 537 | WP_014573068.1 | phosphopantothenoylcysteine decarboxylase | - |
| LLF72_RS02970 (LLF72_02890) | - | 571542..572237 (-) | 696 | WP_011675580.1 | phosphopantothenate--cysteine ligase | - |
| LLF72_RS02975 (LLF72_02895) | - | 572347..572568 (-) | 222 | WP_015082124.1 | 2-hydroxymuconate tautomerase | - |
| LLF72_RS02980 (LLF72_02900) | - | 572754..575081 (+) | 2328 | Protein_560 | cation-translocating P-type ATPase | - |
| LLF72_RS02985 (LLF72_02905) | - | 575114..575308 (+) | 195 | WP_051013160.1 | hypothetical protein | - |
| LLF72_RS02990 (LLF72_02910) | - | 575329..576440 (+) | 1112 | WP_127005270.1 | IS3-like element IS981 family transposase | - |
| LLF72_RS02995 (LLF72_02915) | - | 576755..577099 (+) | 345 | WP_014573064.1 | hypothetical protein | - |
| LLF72_RS03000 (LLF72_02920) | - | 577177..577959 (+) | 783 | WP_014573063.1 | hypothetical protein | - |
| LLF72_RS03005 (LLF72_02925) | - | 578166..578483 (+) | 318 | WP_014573062.1 | hypothetical protein | - |
| LLF72_RS03010 (LLF72_02930) | - | 578483..579517 (+) | 1035 | Protein_566 | cell division protein FtsK | - |
| LLF72_RS03015 (LLF72_02940) | - | 579676..580719 (+) | 1044 | WP_011675590.1 | hypothetical protein | - |
| LLF72_RS03020 (LLF72_02945) | - | 580725..580934 (+) | 210 | WP_014573057.1 | hypothetical protein | - |
| LLF72_RS03025 (LLF72_02950) | - | 580994..582118 (+) | 1125 | WP_015082126.1 | site-specific integrase | - |
| LLF72_RS03030 (LLF72_02955) | - | 582288..582857 (+) | 570 | WP_011675593.1 | thymidine kinase | - |
| LLF72_RS03035 (LLF72_02960) | - | 582868..583311 (+) | 444 | WP_011675594.1 | hypothetical protein | - |
| LLF72_RS03040 (LLF72_02965) | prfA | 583329..584402 (+) | 1074 | WP_011675595.1 | peptide chain release factor 1 | - |
| LLF72_RS03045 (LLF72_02970) | - | 584402..584929 (+) | 528 | WP_015082127.1 | hypothetical protein | - |
| LLF72_RS03050 (LLF72_02975) | nfsA | 584999..585754 (+) | 756 | WP_011675598.1 | oxygen-insensitive NADPH nitroreductase | - |
| LLF72_RS03055 (LLF72_02980) | prmC | 585859..586674 (+) | 816 | WP_015082128.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| LLF72_RS03060 (LLF72_02985) | - | 586705..587169 (+) | 465 | WP_011675600.1 | GNAT family N-acetyltransferase | - |
| LLF72_RS03065 (LLF72_02990) | - | 587193..588086 (+) | 894 | WP_257590455.1 | L-threonylcarbamoyladenylate synthase | - |
| LLF72_RS03070 (LLF72_02995) | glyA | 588319..589566 (+) | 1248 | WP_015082129.1 | serine hydroxymethyltransferase | - |
| LLF72_RS03075 (LLF72_03000) | - | 589747..590349 (+) | 603 | WP_015082130.1 | lysozyme family protein | - |
| LLF72_RS03080 (LLF72_03005) | serC | 590476..591573 (+) | 1098 | WP_015082131.1 | 3-phosphoserine/phosphohydroxythreonine transaminase | - |
| LLF72_RS03085 (LLF72_03010) | - | 591570..592766 (+) | 1197 | WP_015082132.1 | 3-phosphoglycerate dehydrogenase family protein | - |
| LLF72_RS03090 (LLF72_03015) | serB | 592812..593474 (+) | 663 | WP_011675606.1 | phosphoserine phosphatase SerB | - |
| LLF72_RS03095 (LLF72_03020) | - | 593517..593804 (-) | 288 | Protein_583 | acylphosphatase | - |
| LLF72_RS03100 (LLF72_03025) | - | 593916..594674 (+) | 759 | WP_015082133.1 | RNA methyltransferase | - |
| LLF72_RS03105 (LLF72_03030) | - | 594886..595275 (-) | 390 | WP_015082134.1 | cupin domain-containing protein | - |
| LLF72_RS03110 | - | 595275..595502 (-) | 228 | WP_011675745.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 748 a.a. Molecular weight: 83252.03 Da Isoelectric Point: 4.7362
>NTDB_id=529174 LLF72_RS02880 WP_015082116.1 555432..557678(+) (clpC) [Lactococcus cremoris strain F.2.7]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALQGQDFNGAASN
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDDDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAESKKNEATKAEDFEKAAHFRDQISKLRELQKQEVT
DEDMPVITEKDIEQIVEQKTQIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKISKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKQLV
ADLIDDKIVISNQTQETAETTDEEVPAE
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALQGQDFNGAASN
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDDDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAESKKNEATKAEDFEKAAHFRDQISKLRELQKQEVT
DEDMPVITEKDIEQIVEQKTQIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKISKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKQLV
ADLIDDKIVISNQTQETAETTDEEVPAE
Nucleotide
Download Length: 2247 bp
>NTDB_id=529174 LLF72_RS02880 WP_015082116.1 555432..557678(+) (clpC) [Lactococcus cremoris strain F.2.7]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGTGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCCTTTAATCCGTTTAACGATATCTTCAGTGCTTTGCAAGGTCAAGATTTTAATGGGGCAGCAAGTAAT
CAAACTCCCCCAACACAAACGGGTGGGCGTGGTCCGCGTGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGGATGCT
AGAAGAATTCGGTATTAATATCACCGAATCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATCA
AACGTGTTATTGAGATTTTAAATCGCAGAACTAAGAATAATCCAGTGCTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCACAAAAAATAGTCGATGACGATGTGCCACAAAAACTGCAAAATAAAGAAGTTATTCGTCTTGA
CGTGGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTCATTATGTTTATTGATGAAATTCATGAAATTGTCGGTGCTGGTTCTGCTGGCGACGGCAATATGGAT
GCAGGTAATATCCTAAAACCGGCTCTTGCACGTGGTGAGCTTCAATTGGTTGGAGCAACAACACTCAACGAATATCGTAT
TATTGAAAAAGATGCGGCACTTGAACGTCGGATGCAACCGGTCAAAGTAGATGAACCATCAGTTGATGAAACAATTACGA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCATGTGAAATACACTGATGAGGCTATTGAAGCAGCTGCTCAT
TTGTCAAATCGTTACATTCAAGACCGATTCTTACCAGATAAAGCCATCGACCTTTTAGATGAATCTGGTTCTAAGAAAAA
TCTGACTTTGAAATTTGTTGACCCTGAGGATATCAATCGTCGAATTGCTGATGCGGAAAGTAAGAAAAATGAAGCAACTA
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCAGTAAACTTCGTGAATTGCAAAAACAAGAAGTTACT
GACGAAGATATGCCAGTCATCACTGAAAAAGATATTGAACAAATTGTTGAACAAAAAACACAAATTCCAGTTGGGGATTT
GAAAGAAAAAGAACAAACTCAGTTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAAGATGAAGCAGTAG
ATAAAATATCAAAAGCAATTCGTCGCTCACGTGTAGGTCTTGGCAAACCTAACCGTCCAATTGGTTCTTTCCTTTTTGTT
GGTCCAACAGGTGTAGGTAAAACCGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGTGAGAGCATGATTCG
TTTTGATATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGTGCGCCTCCAGGATATGTAGGTTATGAAG
AAGCGGGTCAATTGACCGAACGTGTTCGTCGTAATCCATACAGTTTGATTTTGCTTGATGAAATTGAAAAAGCTCATCCT
GATGTCATGCACATGTTCTTACAAATTCTTGAAGATGGCCGTCTGACAGATGCACAAGGACGGACAGTATCCTTCAAAGA
TAGTTTGATTATCATGACTTCAAATGCCGGAACTGGTAAAGTTGAAGCTTCTGTTGGATTTGGTGCAGCCCGCGAAGGAC
GAACTAAATCAGTGCTTGGTCAACTTGGTGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATTATTGAATTC
TCTGCTTTAAGCAAAGAAAATCTCCTTAAAATTGTTGATTTAATGCTTGATGAAGTCAATGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCCGCTAAAGAAAAATTAGTGGACTTAGGATATAACCCTGCAATGGGTGCAAGACCTC
TTCGTAGAACAATTCAAGAAAATATTGAAGATTCAATTGCTGATTTCTACATTGAACATCCTGAATATAAACAATTGGTA
GCTGATTTGATTGATGATAAAATTGTCATTTCTAATCAAACCCAAGAAACAGCAGAAACCACTGATGAAGAAGTTCCTGC
CGAATAA
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGTGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCCTTTAATCCGTTTAACGATATCTTCAGTGCTTTGCAAGGTCAAGATTTTAATGGGGCAGCAAGTAAT
CAAACTCCCCCAACACAAACGGGTGGGCGTGGTCCGCGTGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGGATGCT
AGAAGAATTCGGTATTAATATCACCGAATCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATCA
AACGTGTTATTGAGATTTTAAATCGCAGAACTAAGAATAATCCAGTGCTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCACAAAAAATAGTCGATGACGATGTGCCACAAAAACTGCAAAATAAAGAAGTTATTCGTCTTGA
CGTGGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTCATTATGTTTATTGATGAAATTCATGAAATTGTCGGTGCTGGTTCTGCTGGCGACGGCAATATGGAT
GCAGGTAATATCCTAAAACCGGCTCTTGCACGTGGTGAGCTTCAATTGGTTGGAGCAACAACACTCAACGAATATCGTAT
TATTGAAAAAGATGCGGCACTTGAACGTCGGATGCAACCGGTCAAAGTAGATGAACCATCAGTTGATGAAACAATTACGA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCATGTGAAATACACTGATGAGGCTATTGAAGCAGCTGCTCAT
TTGTCAAATCGTTACATTCAAGACCGATTCTTACCAGATAAAGCCATCGACCTTTTAGATGAATCTGGTTCTAAGAAAAA
TCTGACTTTGAAATTTGTTGACCCTGAGGATATCAATCGTCGAATTGCTGATGCGGAAAGTAAGAAAAATGAAGCAACTA
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCAGTAAACTTCGTGAATTGCAAAAACAAGAAGTTACT
GACGAAGATATGCCAGTCATCACTGAAAAAGATATTGAACAAATTGTTGAACAAAAAACACAAATTCCAGTTGGGGATTT
GAAAGAAAAAGAACAAACTCAGTTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAAGATGAAGCAGTAG
ATAAAATATCAAAAGCAATTCGTCGCTCACGTGTAGGTCTTGGCAAACCTAACCGTCCAATTGGTTCTTTCCTTTTTGTT
GGTCCAACAGGTGTAGGTAAAACCGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGTGAGAGCATGATTCG
TTTTGATATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGTGCGCCTCCAGGATATGTAGGTTATGAAG
AAGCGGGTCAATTGACCGAACGTGTTCGTCGTAATCCATACAGTTTGATTTTGCTTGATGAAATTGAAAAAGCTCATCCT
GATGTCATGCACATGTTCTTACAAATTCTTGAAGATGGCCGTCTGACAGATGCACAAGGACGGACAGTATCCTTCAAAGA
TAGTTTGATTATCATGACTTCAAATGCCGGAACTGGTAAAGTTGAAGCTTCTGTTGGATTTGGTGCAGCCCGCGAAGGAC
GAACTAAATCAGTGCTTGGTCAACTTGGTGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATTATTGAATTC
TCTGCTTTAAGCAAAGAAAATCTCCTTAAAATTGTTGATTTAATGCTTGATGAAGTCAATGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCCGCTAAAGAAAAATTAGTGGACTTAGGATATAACCCTGCAATGGGTGCAAGACCTC
TTCGTAGAACAATTCAAGAAAATATTGAAGATTCAATTGCTGATTTCTACATTGAACATCCTGAATATAAACAATTGGTA
GCTGATTTGATTGATGATAAAATTGTCATTTCTAATCAAACCCAAGAAACAGCAGAAACCACTGATGAAGAAGTTCCTGC
CGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Lactococcus lactis subsp. cremoris KW2 |
99.733 |
100 |
0.997 |
| clpE | Streptococcus mutans UA159 |
75.762 |
100 |
0.765 |
| clpE | Streptococcus pneumoniae Rx1 |
75.679 |
98.396 |
0.745 |
| clpE | Streptococcus pneumoniae D39 |
75.679 |
98.396 |
0.745 |
| clpE | Streptococcus pneumoniae R6 |
75.679 |
98.396 |
0.745 |
| clpE | Streptococcus pneumoniae TIGR4 |
75.679 |
98.396 |
0.745 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
48.664 |
95.053 |
0.463 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
46.87 |
87.567 |
0.41 |
| clpC | Streptococcus pneumoniae Rx1 |
46.795 |
83.422 |
0.39 |
| clpC | Streptococcus pneumoniae D39 |
46.795 |
83.422 |
0.39 |
| clpC | Streptococcus pneumoniae TIGR4 |
46.795 |
83.422 |
0.39 |
| clpC | Streptococcus thermophilus LMD-9 |
46.266 |
82.353 |
0.381 |
| clpC | Streptococcus thermophilus LMG 18311 |
46.104 |
82.353 |
0.38 |
| clpC | Streptococcus mutans UA159 |
45.631 |
82.62 |
0.377 |