Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   K8B93_RS22685 Genome accession   NZ_CP082772
Coordinates   4679490..4680122 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O2:H1 strain HM670     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4674490..4685122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8B93_RS22660 (K8B93_22525) yheS 4674659..4676572 (+) 1914 WP_000634808.1 ABC transporter ATP-binding protein -
  K8B93_RS22665 (K8B93_22530) yheT 4676572..4677594 (+) 1023 WP_000057387.1 hydrolase -
  K8B93_RS22670 (K8B93_22535) yheU 4677588..4677806 (+) 219 WP_000907085.1 YheU family protein -
  K8B93_RS22675 (K8B93_22540) prkB 4677860..4678729 (+) 870 WP_001617305.1 phosphoribulokinase -
  K8B93_RS22680 (K8B93_22545) yhfA 4678784..4679188 (-) 405 WP_001148908.1 OsmC family protein -
  K8B93_RS22685 (K8B93_22550) crp 4679490..4680122 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  K8B93_RS22690 (K8B93_22555) yhfK 4680173..4682263 (+) 2091 WP_001304921.1 YccS/YhfK family putative transporter -
  K8B93_RS22695 (K8B93_22560) argD 4682330..4683550 (-) 1221 WP_000963800.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  K8B93_RS22700 (K8B93_22565) pabA 4683636..4684199 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  K8B93_RS22705 (K8B93_22570) fic 4684231..4684833 (-) 603 WP_001280638.1 putative adenosine monophosphate-protein transferase Fic -
  K8B93_RS22710 (K8B93_22575) yhfG 4684823..4684990 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=528637 K8B93_RS22685 WP_000242755.1 4679490..4680122(+) (crp) [Escherichia coli O2:H1 strain HM670]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=528637 K8B93_RS22685 WP_000242755.1 4679490..4680122(+) (crp) [Escherichia coli O2:H1 strain HM670]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAATCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467