Detailed information NTG0528573

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JG553_RS06855
• Genome accession: NZ_CP068247
• Coordinates: 1395006..1396049 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus sp. T93
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1390006..1401049

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JG553_RS06825 (JG553_06825)	-	1390424..1391680 (-)	1257	WP_001795438.1	aminopeptidase	-
JG553_RS06830 (JG553_06830)	-	1391683..1391883 (-)	201	WP_000180461.1	DUF1128 family protein	-
JG553_RS06835 (JG553_06835)	-	1392030..1392494 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
JG553_RS06840 (JG553_06840)	-	1392501..1392776 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
JG553_RS06845 (JG553_06845)	-	1393054..1394271 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
JG553_RS06850 (JG553_06850)	vraR	1394387..1395016 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
JG553_RS06855 (JG553_06855)	vraS	1395006..1396049 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JG553_RS06860 (JG553_06860)	liaF	1396046..1396747 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
JG553_RS06865 (JG553_06865)	-	1396762..1397148 (-)	387	WP_001110179.1	hypothetical protein	-
JG553_RS06870 (JG553_06870)	map	1397365..1398123 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
JG553_RS06875 (JG553_06875)	-	1398651..1399637 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
JG553_RS06880 (JG553_06880)	-	1400068..1400481 (-)	414	WP_001549145.1	hypothetical protein	-
JG553_RS06885 (JG553_06885)	-	1400510..1400620 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=528573 JG553_RS06855 WP_001017131.1 1395006..1396049(-) (vraS) [Staphylococcus sp. T93]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=528573 JG553_RS06855 WP_001017131.1 1395006..1396049(-) (vraS) [Staphylococcus sp. T93]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1