Detailed information NTG0528164

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6J08_RS01010
• Genome accession: NZ_CP068219
• Coordinates: 199397..200440 (+)
• Length: 347 a.a.
• NCBI ID: WP_017637854.1
• Uniprot ID: A0A654BBJ5
• Organism: Staphylococcus pasteuri strain FDAARGOS_1151
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 194397..205440

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J08_RS00985 (I6J08_00985)	-	195129..195854 (+)	726	WP_017637859.1	type 1 glutamine amidotransferase	-
I6J08_RS00990 (I6J08_00990)	-	196240..197226 (-)	987	WP_017637858.1	FUSC family protein	-
I6J08_RS00995 (I6J08_00995)	map	197392..198147 (+)	756	WP_208970217.1	type I methionyl aminopeptidase	-
I6J08_RS01000 (I6J08_01000)	-	198298..198684 (+)	387	WP_017637856.1	DUF2543 family protein	-
I6J08_RS01005 (I6J08_01005)	liaF	198699..199400 (+)	702	WP_017637855.1	cell wall-active antibiotics response protein LiaF	-
I6J08_RS01010 (I6J08_01010)	vraS	199397..200440 (+)	1044	WP_017637854.1	sensor histidine kinase	Regulator
I6J08_RS01015 (I6J08_01015)	vraR	200430..201059 (+)	630	WP_017637853.1	two-component system response regulator VraR	Regulator
I6J08_RS01020 (I6J08_01020)	-	201150..202388 (-)	1239	WP_017637852.1	YihY/virulence factor BrkB family protein	-
I6J08_RS01025 (I6J08_01025)	-	202678..202962 (-)	285	WP_017637851.1	hypothetical protein	-
I6J08_RS01030 (I6J08_01030)	-	202967..203431 (-)	465	WP_017637850.1	low molecular weight protein-tyrosine-phosphatase	-
I6J08_RS01035 (I6J08_01035)	-	203593..203775 (+)	183	WP_037555624.1	DUF1128 domain-containing protein	-
I6J08_RS01040 (I6J08_01040)	-	203789..205030 (+)	1242	WP_017637848.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40047.46 Da
• Isoelectric Point: 6.2449

>NTDB_id=528164 I6J08_RS01010 WP_017637854.1 199397..200440(+) (vraS) [Staphylococcus pasteuri strain FDAARGOS_1151]
MNHYIRAIGSMLILTYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWINS
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=528164 I6J08_RS01010 WP_017637854.1 199397..200440(+) (vraS) [Staphylococcus pasteuri strain FDAARGOS_1151]
ATGAATCACTATATAAGAGCAATAGGCTCTATGCTCATTTTAACGTATAGTATGTTAACCGCATTTTTATTTATTGATAA
AGTATTTGTTAACATCATCTATTTTCAAGGTATGTTCTATACACAGATTTTTGGCATACCTGTATTCTTATTTTTAAATA
TCATAGTGATATTATTATGTATCATTGTAGGCTCTGTTTTAGCTTATAAAATTAATCAACAGAATGACTGGATTAATTCT
CAAATAGAACGATCTATTGAAGGTGAAACAGTTGGTATCAATGACCAAAATATAGAATTATATAGTGAAACACTGGAAAT
ATATCATACACTTGTACCATTAAATCAGGAATTACATCGATTAAGAATGAAAACACAAAATTTAACAAATGAAAACTACA
ACATGAACGATGTAAAAGTTAAAAAGATTATTGAAGATGAACGGCAGCGTCTAGCTAGAGAATTACATGACTCAGTAAGT
CAACAATTATTCGCTGCGAGTATGATGTTATCAGCGATTAAAGAAACTAAATTAGAACCCCCATTAGACCAACAAATTCC
AGTTTTAGAGAAAATGGTACAAGATTCACAACTTGAAATGAGAGCTTTATTATTACATTTACGACCTCTAGGGTTGAAAG
ATAAGTCCTTAGGTGAAGGAATTAAAGATTTAGTTATAGATCTTCAAAAGAAAGTTCCGATGAAAGTTGTACATGAAATA
CAAGAATTTAAAGTTCCTAAAGGTATCGAAGATCATTTATTTAGAATTACTCAAGAAGCTATTTCAAATACATTAAGACA
TTCTAATGGCACTAGAGTGACGGTTGAACTATTTAATAAGCAAGATTATTTATTATTACGTATACAAGATAATGGTAAAG
GCTTTAATGTAGATGAAAAATTGGAACAAAGCTATGGTTTAAAAAATATGAGAGAACGTGCATTAGAAATTGGTGCTACA
TTCCATATCGTTTCGTTACCTGATTCCGGAACACGTATAGAAGTTAAAGCCCCATTGAACAAGGAGGATTCTTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A654BBJ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.524	100	0.945