Detailed information NTG0052761

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: YYK_RS07335
• Genome accession: NC_018526
• Coordinates: 1480246..1481295 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis S735
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1475246..1486295

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
YYK_RS07315 (YYK_07110)	nadE	1475652..1476476 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
YYK_RS07320 (YYK_07115)	-	1477772..1478299 (-)	528	WP_012027591.1	VanZ family protein	-
YYK_RS07325 (YYK_07120)	rlmN	1478296..1479408 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
YYK_RS07330 (YYK_07125)	-	1479417..1480058 (-)	642	WP_012027595.1	YutD family protein	-
YYK_RS07335 (YYK_07130)	sepM	1480246..1481295 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
YYK_RS07340 (YYK_07135)	coaD	1481282..1481770 (-)	489	WP_014917298.1	pantetheine-phosphate adenylyltransferase	-
YYK_RS07345 (YYK_07140)	rsmD	1481760..1482299 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
YYK_RS07350 (YYK_07145)	-	1482607..1483329 (-)	723	WP_012027598.1	lipoprotein	-
YYK_RS07355 (YYK_07150)	-	1483386..1483772 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
YYK_RS07360 (YYK_07155)	-	1483772..1483990 (-)	219	WP_004194736.1	YqgQ family protein	-
YYK_RS07365 (YYK_07160)	-	1484298..1484900 (-)	603	WP_012027601.1	response regulator transcription factor	-
YYK_RS07370 (YYK_07165)	-	1484897..1485991 (-)	1095	WP_024383662.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=52761 YYK_RS07335 WP_012775295.1 1480246..1481295(-) (sepM) [Streptococcus suis S735]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=52761 YYK_RS07335 WP_012775295.1 1480246..1481295(-) (sepM) [Streptococcus suis S735]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605