Detailed information NTG0527489

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6I43_RS04265
• Genome accession: NZ_CP068143
• Coordinates: 836974..838017 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_1086
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 831974..843017

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I43_RS04235 (I6I43_04235)	-	832341..832451 (+)	111	WP_001790257.1	hypothetical protein	-
I6I43_RS04240 (I6I43_04240)	-	832480..832893 (+)	414	WP_001670387.1	hypothetical protein	-
I6I43_RS04245 (I6I43_04245)	-	833383..834369 (-)	987	WP_000999716.1	FUSC family protein	-
I6I43_RS04250 (I6I43_04250)	map	834900..835658 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
I6I43_RS04255 (I6I43_04255)	-	835875..836261 (+)	387	WP_001110179.1	hypothetical protein	-
I6I43_RS04260 (I6I43_04260)	liaF	836276..836977 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
I6I43_RS04265 (I6I43_04265)	vraS	836974..838017 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
I6I43_RS04270 (I6I43_04270)	vraR	838007..838636 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
I6I43_RS04275 (I6I43_04275)	-	838748..839965 (-)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
I6I43_RS04280 (I6I43_04280)	-	840243..840518 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
I6I43_RS04285 (I6I43_04285)	-	840525..840989 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
I6I43_RS04290 (I6I43_04290)	-	841136..841336 (+)	201	WP_000180460.1	DUF1128 family protein	-
I6I43_RS04295 (I6I43_04295)	-	841339..842595 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=527489 I6I43_RS04265 WP_001017131.1 836974..838017(+) (vraS) [Staphylococcus aureus strain FDAARGOS_1086]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=527489 I6I43_RS04265 WP_001017131.1 836974..838017(+) (vraS) [Staphylococcus aureus strain FDAARGOS_1086]
ATGAACCATTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1