Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   I6I43_RS03525 Genome accession   NZ_CP068143
Coordinates   715407..716123 (-) Length   238 a.a.
NCBI ID   WP_201802265.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FDAARGOS_1086     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 710407..721123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I43_RS03505 (I6I43_03505) - 711499..712449 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  I6I43_RS03510 (I6I43_03510) - 712598..714082 (+) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  I6I43_RS03515 (I6I43_03515) - 714079..715038 (+) 960 WP_001253310.1 carbohydrate kinase family protein -
  I6I43_RS03520 (I6I43_03520) - 715226..715335 (-) 110 Protein_693 hypothetical protein -
  I6I43_RS03525 (I6I43_03525) agrA 715407..716123 (-) 717 WP_201802265.1 quorum-sensing response regulator AgrA Regulator
  I6I43_RS03530 (I6I43_03530) agrC 716142..717434 (-) 1293 WP_001789596.1 quorum-sensing sensor histidine kinase AgrC -
  I6I43_RS03535 (I6I43_03535) agrD 717459..717599 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  I6I43_RS03540 (I6I43_03540) agrB 717596..718165 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  I6I43_RS13675 hld 718455..718535 (+) 81 WP_000046022.1 delta-hemolysin -
  I6I43_RS03550 (I6I43_03550) - 719132..719917 (-) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  I6I43_RS03555 (I6I43_03555) - 720278..720904 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27907.83 Da        Isoelectric Point: 6.0927

>NTDB_id=527487 I6I43_RS03525 WP_201802265.1 715407..716123(-) (agrA) [Staphylococcus aureus strain FDAARGOS_1086]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGSKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=527487 I6I43_RS03525 WP_201802265.1 715407..716123(-) (agrA) [Staphylococcus aureus strain FDAARGOS_1086]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTAGCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992