Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   K6976_RS00390 Genome accession   NZ_CP082202
Coordinates   66268..68205 (+) Length   645 a.a.
NCBI ID   WP_222759597.1    Uniprot ID   -
Organism   Streptococcus suis strain SS389     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 61268..73205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6976_RS00370 (K6976_00370) tnpA 61514..61895 (+) 382 Protein_54 IS200/IS605 family transposase -
  K6976_RS00375 (K6976_00375) comR 62109..63008 (+) 900 WP_141597428.1 helix-turn-helix domain-containing protein Regulator
  K6976_RS00380 (K6976_00380) - 63216..64436 (+) 1221 WP_222759593.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  K6976_RS00385 (K6976_00385) - 64627..66150 (+) 1524 WP_222759595.1 quinol oxidase -
  K6976_RS00390 (K6976_00390) hexB 66268..68205 (+) 1938 WP_222759597.1 DNA mismatch repair endonuclease MutL Machinery gene
  K6976_RS00395 (K6976_00395) ruvA 68235..68825 (+) 591 WP_044677093.1 Holliday junction branch migration protein RuvA Machinery gene
  K6976_RS00400 (K6976_00400) - 69455..70024 (+) 570 WP_170241530.1 DNA-3-methyladenine glycosylase I -
  K6976_RS00405 (K6976_00405) cinA 70061..71242 (+) 1182 WP_222759599.1 competence/damage-inducible protein A Machinery gene
  K6976_RS00410 (K6976_00410) recA 71294..72445 (+) 1152 WP_024385069.1 recombinase RecA Machinery gene
  K6976_RS00415 (K6976_00415) spx 72681..73079 (+) 399 WP_002939362.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72874.09 Da        Isoelectric Point: 5.1119

>NTDB_id=527006 K6976_RS00390 WP_222759597.1 66268..68205(+) (hexB) [Streptococcus suis strain SS389]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASVSHMVIETATADSTHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VCSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTVGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPAENK
LTSVQFAERQSVKSENQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGETGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=527006 K6976_RS00390 WP_222759597.1 66268..68205(+) (hexB) [Streptococcus suis strain SS389]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTTAAAA
TGATTCAAATCACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAGTCAATCGGATTTGTTTCGTATTCGTACCCTCGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTCAG
TCATATGGTTATTGAGACAGCTACGGCAGACTCTACACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCCGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTTGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCTTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGTAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCCGAAGACTTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTTATCAACGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGTTGGCAGTCATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTTAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTTATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTTTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGCCGAAAATAAA
CTTACCTCTGTTCAATTTGCAGAACGTCAGTCGGTGAAATCAGAAAATCAAGAGCATCCCAATCTAAGCGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCACGGGA
CGTATTTATTTGCACAAGGCGAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCCTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGATGCCCTTCGTCAAGTAGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCAATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GCCCAGTCTTAGTACATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAGGAAAATCACACGAGTTTACGA
GAATTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(447-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.308

100

0.729