Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | I6J04_RS06060 | Genome accession | NZ_CP068079 |
| Coordinates | 1203709..1205340 (-) | Length | 543 a.a. |
| NCBI ID | WP_046099760.1 | Uniprot ID | A0AAJ0JQG2 |
| Organism | Staphylococcus carnosus strain FDAARGOS_1147 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 1203879..1260949 | 1203709..1205340 | flank | -1461 |
Gene organization within MGE regions
Location: 1203709..1260949
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6J04_RS06060 (I6J04_06060) | ccrB | 1203709..1205340 (-) | 1632 | WP_046099760.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I6J04_RS06065 (I6J04_06065) | ccrA | 1205361..1206710 (-) | 1350 | WP_046099890.1 | cassette chromosome recombinase CcrA | Machinery gene |
| I6J04_RS06070 (I6J04_06070) | - | 1206902..1207177 (-) | 276 | WP_046099761.1 | hypothetical protein | - |
| I6J04_RS06075 (I6J04_06075) | cch1 | 1207246..1209033 (-) | 1788 | WP_046099762.1 | cassette chromosome replicative helicase | - |
| I6J04_RS06080 (I6J04_06080) | ssb | 1209033..1209326 (-) | 294 | WP_046099763.1 | cassette chromosome ssDNA-binding protein | - |
| I6J04_RS06085 (I6J04_06085) | - | 1209463..1210512 (+) | 1050 | WP_046099764.1 | hypothetical protein | - |
| I6J04_RS06090 (I6J04_06090) | - | 1210551..1211852 (+) | 1302 | WP_046099765.1 | ATP-binding protein | - |
| I6J04_RS13800 | - | 1212264..1212359 (+) | 96 | Protein_1202 | hypothetical protein | - |
| I6J04_RS06095 (I6J04_06095) | - | 1212375..1213709 (+) | 1335 | WP_414075500.1 | four-carbon acid sugar kinase family protein | - |
| I6J04_RS06100 (I6J04_06100) | - | 1213728..1215089 (+) | 1362 | WP_046099766.1 | gluconate:H+ symporter | - |
| I6J04_RS06105 (I6J04_06105) | - | 1215982..1216719 (+) | 738 | WP_046099892.1 | GntR family transcriptional regulator | - |
| I6J04_RS06110 (I6J04_06110) | deoD | 1217062..1217769 (+) | 708 | WP_046099767.1 | purine-nucleoside phosphorylase | - |
| I6J04_RS06115 (I6J04_06115) | - | 1217782..1219137 (+) | 1356 | WP_046099768.1 | tetracycline resistance MFS efflux pump | - |
| I6J04_RS06120 (I6J04_06120) | deoC | 1219151..1219813 (+) | 663 | WP_046099769.1 | deoxyribose-phosphate aldolase | - |
| I6J04_RS06125 (I6J04_06125) | deoB | 1219842..1221020 (+) | 1179 | WP_046099770.1 | phosphopentomutase | - |
| I6J04_RS06130 (I6J04_06130) | - | 1221066..1221194 (-) | 129 | Protein_1210 | NAD-dependent protein deacylase | - |
| I6J04_RS06135 (I6J04_06135) | ccrB | 1221596..1223224 (-) | 1629 | WP_046099772.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I6J04_RS06140 (I6J04_06140) | ccrA | 1223245..1224594 (-) | 1350 | WP_046099773.1 | cassette chromosome recombinase CcrA | Machinery gene |
| I6J04_RS06145 (I6J04_06145) | - | 1224980..1225753 (+) | 774 | WP_046099774.1 | acetoin reductase | - |
| I6J04_RS06150 (I6J04_06150) | - | 1225956..1227248 (+) | 1293 | WP_046099775.1 | NtaA/DmoA family FMN-dependent monooxygenase | - |
| I6J04_RS06155 (I6J04_06155) | - | 1228046..1228897 (+) | 852 | WP_046099776.1 | LEM-3-like GIY-YIG domain-containing protein | - |
| I6J04_RS06160 (I6J04_06160) | - | 1228927..1230936 (+) | 2010 | WP_046099777.1 | hypothetical protein | - |
| I6J04_RS06165 (I6J04_06165) | - | 1231134..1232243 (+) | 1110 | WP_046099778.1 | DNA polymerase | - |
| I6J04_RS06170 (I6J04_06170) | - | 1232236..1232604 (+) | 369 | WP_046099779.1 | hypothetical protein | - |
| I6J04_RS06175 (I6J04_06175) | - | 1232604..1234247 (+) | 1644 | WP_046099780.1 | DUF5906 domain-containing protein | - |
| I6J04_RS06180 (I6J04_06180) | ccrC | 1234472..1236148 (+) | 1677 | WP_046099781.1 | cassette chromosome recombinase CcrC | - |
| I6J04_RS06185 (I6J04_06185) | - | 1236254..1236592 (+) | 339 | WP_037576898.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I6J04_RS06190 (I6J04_06190) | - | 1236688..1236999 (+) | 312 | WP_046099782.1 | DUF960 family protein | - |
| I6J04_RS06195 (I6J04_06195) | - | 1237014..1237520 (+) | 507 | WP_046099783.1 | DUF1643 domain-containing protein | - |
| I6J04_RS06200 (I6J04_06200) | - | 1237548..1237994 (+) | 447 | WP_046099784.1 | JAB domain-containing protein | - |
| I6J04_RS06205 (I6J04_06205) | - | 1238164..1239036 (+) | 873 | WP_046099785.1 | HTH domain-containing protein | - |
| I6J04_RS06210 (I6J04_06210) | - | 1239093..1239383 (+) | 291 | WP_046099786.1 | hypothetical protein | - |
| I6J04_RS06215 (I6J04_06215) | - | 1239399..1239725 (+) | 327 | WP_235318575.1 | hypothetical protein | - |
| I6J04_RS13500 | - | 1239731..1239889 (+) | 159 | WP_235318576.1 | hypothetical protein | - |
| I6J04_RS06220 (I6J04_06220) | - | 1240028..1240591 (+) | 564 | WP_046099787.1 | hypothetical protein | - |
| I6J04_RS13505 | - | 1240611..1241156 (+) | 546 | WP_046099788.1 | hypothetical protein | - |
| I6J04_RS06230 (I6J04_06230) | galU | 1241449..1242316 (+) | 868 | Protein_1231 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| I6J04_RS06235 (I6J04_06235) | - | 1242575..1243696 (+) | 1122 | WP_046099789.1 | glycosyltransferase family 2 protein | - |
| I6J04_RS06240 (I6J04_06240) | - | 1243696..1245723 (+) | 2028 | WP_046099790.1 | CDP-glycerol--glycerophosphate glycerophosphotransferase | - |
| I6J04_RS06245 (I6J04_06245) | - | 1245733..1247370 (+) | 1638 | WP_052719452.1 | DUF6270 domain-containing protein | - |
| I6J04_RS06250 (I6J04_06250) | - | 1247590..1248906 (+) | 1317 | WP_046099791.1 | glycosyltransferase family 2 protein | - |
| I6J04_RS06255 (I6J04_06255) | - | 1249380..1252172 (+) | 2793 | WP_046099792.1 | type I restriction endonuclease subunit R | - |
| I6J04_RS06260 (I6J04_06260) | - | 1252262..1252843 (+) | 582 | WP_046099793.1 | restriction endonuclease subunit S | - |
| I6J04_RS06265 (I6J04_06265) | - | 1252844..1254400 (+) | 1557 | WP_046099794.1 | type I restriction-modification system subunit M | - |
| I6J04_RS06270 (I6J04_06270) | - | 1254393..1255619 (+) | 1227 | WP_046099795.1 | restriction endonuclease subunit S | - |
| I6J04_RS06275 (I6J04_06275) | - | 1255670..1255918 (+) | 249 | WP_046099796.1 | hypothetical protein | - |
| I6J04_RS06280 (I6J04_06280) | - | 1255983..1256204 (-) | 222 | WP_046099797.1 | hypothetical protein | - |
| I6J04_RS06285 (I6J04_06285) | - | 1256219..1256719 (-) | 501 | WP_046099798.1 | DUF1643 domain-containing protein | - |
| I6J04_RS06290 (I6J04_06290) | - | 1256733..1257044 (-) | 312 | WP_046099799.1 | DUF960 family protein | - |
| I6J04_RS06295 (I6J04_06295) | - | 1257140..1257478 (-) | 339 | Protein_1244 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I6J04_RS06300 (I6J04_06300) | ccrB | 1257953..1259578 (-) | 1626 | WP_046099800.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I6J04_RS06305 (I6J04_06305) | ccrA | 1259600..1260949 (-) | 1350 | WP_046099801.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 543 a.a. Molecular weight: 62456.43 Da Isoelectric Point: 9.5994
>NTDB_id=526969 I6J04_RS06060 WP_046099760.1 1203709..1205340(-) (ccrB) [Staphylococcus carnosus strain FDAARGOS_1147]
MQQLKQKRVGIYVRVSTEMQSAEGYSIDGQINQIKEYCNFHHFEVKDIYADRGISGKSMNRPALQRMLHDANKGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFEINTILENIYTGQHQRALEGYYQGN
LPLGYNNIPDNKKDLMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAK
YKDWNDKRRKGLNDKPVIAEGKHTPIISQSLWDKVQARKKQVSEKPQVHGKGTNILTGLISCPQCSASMSASTTVNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQEHQIDTSALNHDIAYKQQQYD
EVQIKLDNLIKTLEDNPDLTSVLKNTIHQYEKQLNDITNQINQLKQQQSAPKTIYDANEIATILRHIFKNIETMDKAQLK
ALYLTVIDHIDIRKDEHHKKQFYVTLKLNHEIIKQLFHNIPLDEVQLSTSSLLLSQTLYLPIS
MQQLKQKRVGIYVRVSTEMQSAEGYSIDGQINQIKEYCNFHHFEVKDIYADRGISGKSMNRPALQRMLHDANKGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFEINTILENIYTGQHQRALEGYYQGN
LPLGYNNIPDNKKDLMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAK
YKDWNDKRRKGLNDKPVIAEGKHTPIISQSLWDKVQARKKQVSEKPQVHGKGTNILTGLISCPQCSASMSASTTVNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQEHQIDTSALNHDIAYKQQQYD
EVQIKLDNLIKTLEDNPDLTSVLKNTIHQYEKQLNDITNQINQLKQQQSAPKTIYDANEIATILRHIFKNIETMDKAQLK
ALYLTVIDHIDIRKDEHHKKQFYVTLKLNHEIIKQLFHNIPLDEVQLSTSSLLLSQTLYLPIS
Nucleotide
Download Length: 1632 bp
>NTDB_id=526969 I6J04_RS06060 WP_046099760.1 1203709..1205340(-) (ccrB) [Staphylococcus carnosus strain FDAARGOS_1147]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATGCAAAGTGCAGAGGGTTATAGTAT
CGACGGTCAAATCAATCAAATCAAAGAATATTGTAACTTCCATCATTTCGAAGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGAAAGTCTATGAACCGCCCTGCACTTCAACGTATGTTACATGATGCGAATAAAGGTCATATTGATTGTGTTATG
GTGTATAAAACAAATCGACTCGCACGTAATACATCAGACTTACTCAAAATTGTCGAAGATTTGCATAAACAAAATGTTGA
ATTTTTCAGTTTGTCTGAGCGTATGGAAGTCAACACTTCTTCTGGTAAACTCATGTTACAAATACTTGCAAGTTTTTCCG
AATTTGAAATAAATACCATTTTAGAGAATATTTACACCGGACAACATCAAAGAGCCTTAGAAGGCTATTACCAAGGTAAT
CTTCCTTTAGGATATAATAACATACCAGATAATAAAAAAGATTTGATGATTAATCAGCATGAAGCTAATATTGTGAAATA
TATTTTTGAATCTTACGCCAAAGGTCATGGTTATCGTAAAATTGCCAACGCACTCAATCATAAAGGTTATGTCACTAAGA
AAGGTAATCCTTTTAGTATTTCAGCTGTTACTTATATTCTCTCAAACCCATTCTATATTGGTAAAATTCAATTCGCGAAA
TACAAAGATTGGAATGATAAACGTCGTAAAGGCTTGAATGATAAACCCGTAATTGCCGAAGGCAAACACACCCCTATTAT
TAGCCAATCATTATGGGATAAAGTCCAAGCACGTAAAAAACAAGTAAGTGAAAAACCACAAGTTCATGGTAAAGGAACCA
ATATTTTAACTGGATTAATTTCGTGTCCCCAATGTTCTGCTTCAATGTCTGCGAGCACAACAGTTAATACACTTAAAGAT
GGTACTAAAAAACGCATTCGCTACTATTCGTGTAGTAACTTTCGTAATAAAGGGTCAAAAGTATGTTCTGCGAATAGTGT
CAGAGCCGATGTAATTGAAAAATATGTTATGGATCAAATACTCGAAATTGTTAAAAGCGACAAGGTTATCAAGCAAGTCG
TTGAGCGTGTCAATCAAGAACATCAAATTGATACGTCTGCACTCAATCATGATATCGCATATAAGCAACAACAATATGAT
GAGGTCCAAATCAAATTAGATAACTTGATAAAAACGCTTGAAGATAATCCAGACTTAACATCTGTGCTTAAAAATACGAT
TCATCAGTATGAAAAACAACTCAATGACATCACAAATCAAATCAATCAACTTAAGCAACAACAAAGTGCTCCCAAAACAA
TATATGACGCTAATGAGATTGCGACTATATTACGTCATATATTCAAAAATATCGAAACCATGGATAAAGCACAACTCAAA
GCACTATACCTTACGGTCATAGACCACATTGATATTCGTAAAGACGAACATCATAAAAAACAGTTCTACGTCACATTAAA
ACTCAATCATGAAATCATTAAACAACTCTTCCATAATATCCCTCTCGACGAAGTGCAACTCAGCACTTCGTCTTTATTAT
TATCTCAAACACTCTATTTGCCTATCTCATAA
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATGCAAAGTGCAGAGGGTTATAGTAT
CGACGGTCAAATCAATCAAATCAAAGAATATTGTAACTTCCATCATTTCGAAGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGAAAGTCTATGAACCGCCCTGCACTTCAACGTATGTTACATGATGCGAATAAAGGTCATATTGATTGTGTTATG
GTGTATAAAACAAATCGACTCGCACGTAATACATCAGACTTACTCAAAATTGTCGAAGATTTGCATAAACAAAATGTTGA
ATTTTTCAGTTTGTCTGAGCGTATGGAAGTCAACACTTCTTCTGGTAAACTCATGTTACAAATACTTGCAAGTTTTTCCG
AATTTGAAATAAATACCATTTTAGAGAATATTTACACCGGACAACATCAAAGAGCCTTAGAAGGCTATTACCAAGGTAAT
CTTCCTTTAGGATATAATAACATACCAGATAATAAAAAAGATTTGATGATTAATCAGCATGAAGCTAATATTGTGAAATA
TATTTTTGAATCTTACGCCAAAGGTCATGGTTATCGTAAAATTGCCAACGCACTCAATCATAAAGGTTATGTCACTAAGA
AAGGTAATCCTTTTAGTATTTCAGCTGTTACTTATATTCTCTCAAACCCATTCTATATTGGTAAAATTCAATTCGCGAAA
TACAAAGATTGGAATGATAAACGTCGTAAAGGCTTGAATGATAAACCCGTAATTGCCGAAGGCAAACACACCCCTATTAT
TAGCCAATCATTATGGGATAAAGTCCAAGCACGTAAAAAACAAGTAAGTGAAAAACCACAAGTTCATGGTAAAGGAACCA
ATATTTTAACTGGATTAATTTCGTGTCCCCAATGTTCTGCTTCAATGTCTGCGAGCACAACAGTTAATACACTTAAAGAT
GGTACTAAAAAACGCATTCGCTACTATTCGTGTAGTAACTTTCGTAATAAAGGGTCAAAAGTATGTTCTGCGAATAGTGT
CAGAGCCGATGTAATTGAAAAATATGTTATGGATCAAATACTCGAAATTGTTAAAAGCGACAAGGTTATCAAGCAAGTCG
TTGAGCGTGTCAATCAAGAACATCAAATTGATACGTCTGCACTCAATCATGATATCGCATATAAGCAACAACAATATGAT
GAGGTCCAAATCAAATTAGATAACTTGATAAAAACGCTTGAAGATAATCCAGACTTAACATCTGTGCTTAAAAATACGAT
TCATCAGTATGAAAAACAACTCAATGACATCACAAATCAAATCAATCAACTTAAGCAACAACAAAGTGCTCCCAAAACAA
TATATGACGCTAATGAGATTGCGACTATATTACGTCATATATTCAAAAATATCGAAACCATGGATAAAGCACAACTCAAA
GCACTATACCTTACGGTCATAGACCACATTGATATTCGTAAAGACGAACATCATAAAAAACAGTTCTACGTCACATTAAA
ACTCAATCATGAAATCATTAAACAACTCTTCCATAATATCCCTCTCGACGAAGTGCAACTCAGCACTTCGTCTTTATTAT
TATCTCAAACACTCTATTTGCCTATCTCATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
82.472 |
99.816 |
0.823 |