Detailed information NTG0526752

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I6J14_RS08825
• Genome accession: NZ_CP068057
• Coordinates: 1746518..1748962 (+)
• Length: 814 a.a.
• NCBI ID: WP_115253166.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain FDAARGOS_1157
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1741518..1753962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J14_RS08795 (I6J14_08795)	-	1742015..1742293 (-)	279	WP_003053031.1	GNAT family N-acetyltransferase	-
I6J14_RS08800 (I6J14_08800)	-	1742409..1743800 (-)	1392	WP_115253167.1	GNAT family N-acetyltransferase	-
I6J14_RS08805 (I6J14_08805)	-	1743787..1744242 (-)	456	WP_003053027.1	MarR family transcriptional regulator	-
I6J14_RS10975	-	1744373..1744684 (-)	312	WP_003053026.1	amidohydrolase family protein	-
I6J14_RS10980	-	1745074..1745250 (-)	177	WP_003053022.1	hypothetical protein	-
I6J14_RS08815 (I6J14_08815)	-	1745657..1745860 (+)	204	WP_115253271.1	cold-shock protein	-
I6J14_RS08820 (I6J14_08820)	-	1746057..1746518 (+)	462	WP_115245552.1	CtsR family transcriptional regulator	-
I6J14_RS08825 (I6J14_08825)	clpC	1746518..1748962 (+)	2445	WP_115253166.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I6J14_RS08830 (I6J14_08830)	groES	1749140..1749430 (+)	291	WP_115253165.1	co-chaperone GroES	-
I6J14_RS08835 (I6J14_08835)	groL	1749466..1751091 (+)	1626	WP_003053011.1	chaperonin GroEL	-
I6J14_RS08840 (I6J14_08840)	-	1751310..1751777 (-)	468	WP_003053009.1	8-oxo-dGTP diphosphatase	-
I6J14_RS08845 (I6J14_08845)	-	1752111..1753607 (-)	1497	WP_003053008.1	C69 family dipeptidase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90325.97 Da
• Isoelectric Point: 6.6502

>NTDB_id=526752 I6J14_RS08825 WP_115253166.1 1746518..1748962(+) (clpC) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MIMYSLKMQEIFRQAQFQAARFDSQYLETWHILLAMARVDHSLAGLVLSEFDAKVAVEEYEAAAILAMGKSPKDQVSHID
FRPQSKTLTNLLQFAQAISQVTKDQEVGSEHVLFAVLLNPDIMATRLLEMAGYAIKDKGNGEPRLADLRKAIEIHAGYSK
EMIKAIHELRKPKKTKNQGSFSDMMKPPSTAGDLADFTRDLTEMASQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNVEDAYQILIGLKGSYETYHNVTIAD
QAVRTAVKMAHRYLTSKNLPDSAIDLLDEASATVQGMVKKTSPEIITPLDQALIDGDMKKASRLLAKDVKGQHRKPTAVT
EEDILTTLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQKDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNILLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGISHDHQAMEKRILEELKKTYRPEFINRIDEKVVFH
SLTQDNMREVVKIMVQPLMTTLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGELASGHTL
KIGLSHGKLSFNIE

Nucleotide

• Length: 2445 bp

>NTDB_id=526752 I6J14_RS08825 WP_115253166.1 1746518..1748962(+) (clpC) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGATCATGTATTCATTGAAGATGCAAGAAATTTTCAGGCAGGCGCAATTTCAAGCAGCCCGCTTTGATAGCCAATACCT
AGAAACTTGGCATATATTGCTAGCTATGGCGAGGGTTGATCACTCCCTAGCGGGTTTGGTGCTAAGCGAATTTGATGCTA
AGGTTGCAGTGGAAGAATATGAGGCTGCAGCTATTTTAGCTATGGGCAAAAGCCCTAAAGACCAAGTGTCTCACATTGAC
TTTAGGCCTCAGTCAAAAACCTTAACGAACCTTTTGCAATTTGCCCAAGCTATCAGTCAAGTCACCAAAGACCAAGAGGT
AGGTTCAGAGCATGTTCTCTTTGCCGTTTTGCTTAATCCAGATATTATGGCGACTCGCTTATTAGAGATGGCTGGTTATG
CTATCAAGGATAAAGGAAACGGAGAACCTCGCTTAGCTGATTTACGAAAAGCTATCGAGATTCATGCAGGCTATAGTAAG
GAAATGATTAAGGCTATCCACGAGTTGCGTAAACCAAAGAAAACCAAGAATCAAGGTTCTTTTTCAGACATGATGAAGCC
ACCAAGCACGGCTGGGGATTTGGCGGACTTTACACGTGATTTGACCGAGATGGCAAGCCAAGGTCTCTTAGAGCCAGTTA
TTGGCCGTGATGCTGAAGTATCACGGATGATCCAAGTACTGAGTCGTAAAACCAAGAATAACCCTGTTCTTGTGGGTGAT
GCAGGTGTGGGTAAAACGGCCCTTGCCTATGGTCTTGCCCAACGTATTGCTAATGGTGCTATTCCTTATGAACTGCAAGA
CATGCGTGTTCTAGAATTAGATATGATGAGTGTTGTTGCGGGGACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGACGATATTGAGTCAGATGGCAAGATTATTCTCTTCGTAGATGAATTGCACACCATTATGGGATCAGGAAGT
GGTATTGATAGCACACTTGATGCTGCCAATATTTTAAAACCAGCCTTATCTCGCGGAACCCTCCATATGGTGGGTGCAAC
AACGCAGGAAGAATACCAAAAACACATTGAAAAAGATGCCGCTCTTTCGCGTCGCTTTGCTAAGATTTTAATTGAAGAGC
CTAATGTAGAAGATGCTTATCAGATTCTGATCGGGTTAAAAGGCTCTTACGAGACTTACCATAATGTGACCATTGCTGAT
CAGGCTGTTAGAACTGCTGTGAAAATGGCACATCGCTATCTGACCAGCAAAAACCTTCCAGATTCTGCCATTGATTTGCT
AGATGAAGCTAGTGCTACTGTCCAAGGTATGGTTAAAAAAACCAGTCCAGAAATCATCACGCCATTAGATCAAGCTTTGA
TTGATGGCGATATGAAGAAGGCCTCTCGTTTGTTGGCAAAAGACGTTAAAGGACAACATCGTAAGCCAACAGCTGTGACA
GAAGAGGATATCCTGACAACCTTGAGCAAGCTATCAGGTATTCCACTGGAAAAACTCAGCCAAGCTGATAGCAAAAAATA
CCTTAATTTGGAAAAAGAACTGCATAAGCGCGTGATTGGGCAAAAAGATGCTGTCTCAGCTATTTCTCGAGCGATTCGTC
GTAATCAGTCAGGCATCCGTACAGGTAAACGTCCGATTGGTTCCTTCATGTTCCTTGGTCCAACAGGGGTTGGTAAGACT
GAGTTGGCTAAAGCCTTGGCAGAAGTTCTCTTTGACGACGCGTCTGCCCTTATCCGCTTTGATATGTCAGAGTATATGGA
AAAATTTGCGGCTTCTCGTCTTAATGGCGCACCTCCAGGCTATGTCGGTTACGATGAAGGTGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTACTCCGTGCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAACATACTCTTACAA
GTGCTTGATGACGGCATGTTGACAGATAGTCGTGGGCGTAAAGTGGACTTCTCAAACACCATTATTATCATGACAAGTAA
TCTAGGGGCAACAGCTCTGCGTGATGATAAAACAGTTGGCTTTGGGGCAAAAGGCATTAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAGAAAACTTACCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAC
AGCCTCACTCAGGATAATATGAGAGAAGTGGTCAAGATTATGGTGCAGCCGTTGATGACTACTTTGGCAGAAAAAGGCAT
TACCCTTAAATTCCAGCCAATGGCCCTCAAGTATTTATCAGAAGAAGGGTACGATGTAGAAATGGGTGCTCGTCCATTGC
GCCGTACTTTGCAAACTCAGGTGGAAGATAAATTGTCTGAATTGATTCTTGCTGGTGAATTGGCAAGTGGTCATACCCTG
AAAATTGGTCTTTCTCATGGAAAACTCAGCTTTAACATTGAGTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• AAA lid domain (AAA_lid_9) (376-461)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-133)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.63	99.877	0.765
clpC	Streptococcus thermophilus LMD-9	73.162	100	0.733
clpC	Streptococcus thermophilus LMG 18311	72.917	100	0.731
clpC	Streptococcus pneumoniae TIGR4	66.79	99.877	0.667
clpC	Streptococcus pneumoniae Rx1	66.79	99.877	0.667
clpC	Streptococcus pneumoniae D39	66.79	99.877	0.667
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.801	100	0.5
clpC	Bacillus subtilis subsp. subtilis str. 168	43.081	100	0.44