Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I6J14_RS08270 Genome accession   NZ_CP068057
Coordinates   1625802..1627022 (-) Length   406 a.a.
NCBI ID   WP_003048956.1    Uniprot ID   A0A380JYG2
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1620802..1632022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS08245 (I6J14_08245) - 1621273..1621638 (-) 366 WP_115252481.1 helix-turn-helix transcriptional regulator -
  I6J14_RS08250 (I6J14_08250) - 1621763..1621960 (-) 198 WP_003048966.1 DUF951 family protein -
  I6J14_RS08255 (I6J14_08255) dnaN 1622035..1623171 (-) 1137 WP_115252480.1 DNA polymerase III subunit beta -
  I6J14_RS08260 (I6J14_08260) dnaA 1623325..1624680 (-) 1356 WP_003048960.1 chromosomal replication initiator protein DnaA -
  I6J14_RS08265 (I6J14_08265) spo0J 1624914..1625687 (-) 774 WP_115253230.1 ParB/RepB/Spo0J family partition protein Regulator
  I6J14_RS08270 (I6J14_08270) htrA 1625802..1627022 (-) 1221 WP_003048956.1 trypsin-like peptidase domain-containing protein Regulator
  I6J14_RS08275 (I6J14_08275) rlmH 1627232..1627711 (+) 480 WP_115253229.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6J14_RS08295 (I6J14_08295) - 1628455..1631061 (-) 2607 WP_115253228.1 YfhO family protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 42695.23 Da        Isoelectric Point: 6.3566

>NTDB_id=526748 I6J14_RS08270 WP_003048956.1 1625802..1627022(-) (htrA) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MPSMKHILKSLGILLIGFLGGLLAIFTFNATQQSSSTSHTSSATMSKMVFNNTTDTTKAVKVVQNAVVSVINYQADPSSS
LSNPYTKLFGENPAREDKDSELTVFAQGSGVIYRKDSNHAYVVTNNHVIDGAKRIEILMADGTKVVGELIGADTYSDLAV
VKISSDKIKTVAEFADSTKLNVGETAIAIGSPLGTQYANSVTKGIVSSLSRTVTLKNEDGETVSTNAIQTDAAINPGNSG
GPLINIEGQVIGINSSKISSTPSGINGNSGAVEGISFAIPSNDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQI
NIPTSITGGIVVGSVQEGMPASGKLAQYDVITEIDGKAVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKTDITLTKTTQ
DLTKKQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=526748 I6J14_RS08270 WP_003048956.1 1625802..1627022(-) (htrA) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGCCATCTATGAAACATATCTTAAAATCCTTAGGCATTTTACTCATTGGATTTTTAGGAGGATTGTTAGCAATTTTCAC
TTTTAATGCTACTCAACAGTCTTCCTCTACCTCACATACTAGTAGTGCGACGATGAGTAAGATGGTTTTTAATAATACTA
CTGACACAACAAAAGCGGTTAAAGTCGTCCAAAACGCAGTAGTATCAGTGATTAACTATCAAGCAGATCCTTCTTCATCT
CTTTCTAATCCTTACACAAAACTCTTTGGAGAAAATCCAGCAAGAGAAGATAAAGATTCCGAATTAACAGTTTTTGCTCA
AGGTTCTGGTGTCATTTATCGAAAAGATTCCAATCATGCCTATGTTGTGACTAATAATCATGTTATTGACGGCGCAAAAC
GAATTGAAATTCTTATGGCAGATGGAACTAAGGTAGTAGGAGAATTAATTGGTGCGGATACTTATTCTGACTTAGCTGTA
GTTAAAATTTCTTCAGATAAGATTAAAACAGTAGCTGAATTTGCAGATTCTACTAAACTTAATGTTGGAGAAACTGCTAT
TGCTATTGGTAGTCCACTGGGAACTCAATACGCAAACTCAGTTACGAAAGGAATTGTATCGAGCCTAAGTCGTACCGTTA
CCTTAAAAAACGAAGATGGAGAAACTGTTTCAACAAATGCTATCCAAACAGATGCTGCTATTAACCCCGGAAATTCTGGG
GGACCACTAATTAATATAGAAGGACAGGTTATCGGTATTAATTCAAGTAAGATTTCTTCTACTCCATCTGGTATTAATGG
GAATAGTGGAGCTGTCGAAGGAATTAGCTTTGCTATTCCATCTAATGATGTCATTAAAATCATTAAGCAATTAGAAACCA
ACGGTGAAGTCATACGACCTGCTCTTGGTATCTCTATGGTTAACCTAAATGATTTATCAACTAATGCTCTTAGTCAAATT
AATATCCCAACTAGTATCACTGGCGGCATTGTGGTTGGTTCTGTTCAAGAGGGAATGCCAGCAAGTGGTAAACTTGCCCA
GTACGATGTCATTACAGAAATTGATGGGAAAGCTGTTAATTCAATAAGTGATCTTCAAAGTAGTCTATATGGCCATGACA
TTAACGATACCATCAAGGTAACCTTTTATAGAGGGACAACCAAGAAAAAAACAGATATTACCTTAACTAAAACAACTCAG
GATTTGACCAAAAAGCAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(300-395)

Trypsin-like peptidase domain (Trypsin_2)

(108-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380JYG2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

59.204

99.015

0.586
  htrA Streptococcus mitis NCTC 12261

54.054

100

0.542
  htrA Streptococcus pneumoniae Rx1

54.054

100

0.542
  htrA Streptococcus pneumoniae TIGR4

54.054

100

0.542
  htrA Streptococcus pneumoniae D39

54.054

100

0.542
  htrA Streptococcus pneumoniae R6

54.054

100

0.542
  htrA Streptococcus gordonii str. Challis substr. CH1

54.208

99.507

0.539