Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   I6J14_RS00655 Genome accession   NZ_CP068057
Coordinates   126957..129248 (-) Length   763 a.a.
NCBI ID   WP_115253001.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1157     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 121957..134248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J14_RS00640 (I6J14_00640) ileS 122817..125618 (+) 2802 WP_003051844.1 isoleucine--tRNA ligase -
  I6J14_RS00645 (I6J14_00645) - 126031..126333 (-) 303 WP_003051842.1 DUF1827 family protein -
  I6J14_RS00650 (I6J14_00650) - 126387..126839 (-) 453 WP_236593276.1 NUDIX hydrolase -
  I6J14_RS00655 (I6J14_00655) clpE 126957..129248 (-) 2292 WP_115253001.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  I6J14_RS00660 (I6J14_00660) - 129547..129777 (+) 231 WP_003051836.1 DUF1797 family protein -
  I6J14_RS00665 (I6J14_00665) - 129905..130591 (+) 687 WP_003051835.1 amino acid ABC transporter permease -
  I6J14_RS00670 (I6J14_00670) - 130591..131325 (+) 735 WP_115246232.1 amino acid ABC transporter ATP-binding protein -
  I6J14_RS00675 (I6J14_00675) - 131523..132001 (+) 479 Protein_130 FeoA domain-containing protein -
  I6J14_RS00680 (I6J14_00680) feoB 131998..134157 (+) 2160 WP_115276446.1 ferrous iron transport protein B -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84943.21 Da        Isoelectric Point: 5.2743

>NTDB_id=526706 I6J14_RS00655 WP_115253001.1 126957..129248(-) (clpE) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MLCQNCNLNESTIHLYTNVNGKQKQVDLCQNCYQIMKTDPTNPILGGLNGGQRAQERSSTPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRHGGHFNGQRPTQPQTQNQQVKGLLEEFGINVTDIARHGDIDPVIGRDDEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIVDGTVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
IAKYKEMQAQKVDEQDIPIITEKTIEAIIEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKDNLLHIVDLMLEDVNKRLGYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKDLRAIMTSNGNVMIKAAKKDETVTAKQDQTDEN

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=526706 I6J14_RS00655 WP_115253001.1 126957..129248(-) (clpE) [Streptococcus dysgalactiae strain FDAARGOS_1157]
ATGCTTTGTCAAAATTGTAATTTAAACGAATCAACCATCCACCTCTACACGAATGTTAATGGAAAACAAAAACAAGTTGA
CCTTTGTCAAAACTGTTATCAAATCATGAAGACTGACCCTACTAATCCTATTTTAGGTGGTCTAAATGGAGGTCAAAGAG
CCCAAGAACGCTCATCCACCCCCTTCTTTGATGACTTTTTTGGTGATTTAAATAATTTTAGAGCCTTTGGTAACCTTCCG
AATACCCCGCCTACACAAGCAGGCCAAAATGGCAACGGAGGAGGACGCCATGGTGGTCATTTCAATGGGCAACGTCCCAC
TCAGCCACAAACACAAAATCAGCAAGTAAAGGGCTTGTTAGAAGAATTTGGGATTAATGTTACAGATATTGCAAGACATG
GTGATATTGACCCTGTCATCGGTCGAGATGACGAGATTACACGTGTCATCGAAATCCTTAACCGTCGGACTAAAAATAAC
CCTGTGCTTATTGGGGAACCAGGAGTTGGTAAAACAGCTGTTGTAGAAGGTCTAGCCCAGAAAATTGTAGATGGCACAGT
ACCTCACAAATTGCAAGGTAAGCAAGTGATTCGTCTAGATGTGGTTAGTCTTGTTCAGGGCACAGGTATCCGTGGTCAAT
TCGAAGAACGCATGCAAAAATTAATGGAAGAAATTCGTCAACGCAAAGATGTGATTCTCTTTATTGATGAAATTCATGAA
ATTGTAGGTGCTGGTTCTGCTGGAGATGGCAATATGGATGCTGGCAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACCTTAAATGAATACCGTATTATTGAAAAAGATGCTGCCTTGGAGCGGCGGATGCAGCCGG
TGAAAGTTGACGAACCTTCTGTAGAAGAAACCATTACCATCTTAAAAGGTATCCAGCCCAAATATGAAGACTATCATCAT
GTCAAATATAGCCCAGCAGCTATCGAGGCTGCTGCACACTTATCCAATCGCTACATTCAAGACCGATTCCTCCCTGATAA
GGCCATTGACCTTCTGGACGAAGCTGGTTCAAAAATGAATTTAACCCTTAATTTTGTTGACCCTAAAGAGATTGACAAAC
GTCTGATTGAAGCAGAAAACCTCAAGGCTCAAGCAACTCGTGACGAAGATTACGAACGAGCAGCCTATTTCCGAGATCAA
ATTGCGAAATACAAGGAAATGCAAGCTCAAAAAGTCGACGAACAGGATATTCCTATCATTACTGAAAAAACCATTGAAGC
CATCATTGAACAAAAAACTAATATTCCAGTTGGCGATTTGAAAGAAAAAGAACAATCTCAACTCGTTAATTTGGCTAATG
ATTTGAAAGCTCACGTGATTGGCCAAGATGATGCCGTTGACAAAATTGCCAAGGCCATTCGCCGGAACCGTGTGGGATTA
GGAACTCCAAATCGTCCTATTGGTTCTTTCCTATTCGTTGGGCCAACAGGTGTTGGTAAAACAGAATTGTCTAAGCAACT
AGCTATTGAACTCTTTGGCTCTGCTGACAATATGATTCGCTTTGACATGTCCGAATACATGGAAAAACATGCCGTTGCTA
AATTAGTCGGGGCTCCTCCTGGTTATGTGGGCTATGAAGAAGCTGGCCAGTTAACGGAACAAGTTCGCCGCAATCCATAT
TCACTTATTCTCTTAGATGAAGTGGAAAAGGCTCATCCTGACGTCATGCACATGTTTTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGAACAGTCAGCTTCAAGGATACTATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GTGAAGCTTCTGTTGGATTTGGTGCAGCTAGAGAAGGACGAACAAGTTCTGTCCTTGGTGAATTAAGTAACTTCTTCAGC
CCAGAGTTCATGAACCGTTTCGATGGTATTATTGAATTTAAGGCCTTGAGCAAAGATAACCTCTTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATAAGCGCTTAGGCTATAATGGGATTCACCTTGATGTGACGCAAAAAGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGTGCTCGACCGCTCCGTCGTACCATCCAAGATTATATCGAAGATGCGATTACG
GACTACTATTTGGAACATCCAACTGAAAAGGACTTGCGTGCCATAATGACAAGTAACGGTAATGTTATGATTAAAGCTGC
CAAAAAAGATGAAACGGTAACAGCTAAACAAGATCAGACCGACGAGAACTAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(162-281)

AAA lid domain (AAA_lid_9)

(300-397)

AAA domain (Cdc48 subfamily) (AAA_2)

(485-648)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(656-730)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.45

99.083

0.847
  clpE Streptococcus pneumoniae Rx1

83.794

99.476

0.834
  clpE Streptococcus pneumoniae D39

83.794

99.476

0.834
  clpE Streptococcus pneumoniae R6

83.794

99.476

0.834
  clpE Streptococcus pneumoniae TIGR4

83.663

99.476

0.832
  clpC Lactococcus lactis subsp. cremoris KW2

76.526

96.592

0.739
  clpC Bacillus subtilis subsp. subtilis str. 168

49.781

89.777

0.447
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.308

85.19

0.394
  clpC Streptococcus pneumoniae Rx1

47.84

81.913

0.392
  clpC Streptococcus pneumoniae D39

47.84

81.913

0.392
  clpC Streptococcus pneumoniae TIGR4

47.84

81.913

0.392
  clpC Streptococcus mutans UA159

47.581

81.258

0.387
  clpC Streptococcus thermophilus LMD-9

46.215

83.093

0.384
  clpC Streptococcus thermophilus LMG 18311

45.899

83.093

0.381