Detailed information NTG0526565

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: K6975_RS03480
• Genome accession: NZ_CP082197
• Coordinates: 712308..713582 (+)
• Length: 424 a.a.
• NCBI ID: WP_012775180.1
• Uniprot ID: A0A0H3MUX4
• Organism: Streptococcus suis strain Transconjugant cSS389
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 707308..718582

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6975_RS03470 (K6975_03470)	-	710695..711504 (+)	810	WP_012027151.1	Cof-type HAD-IIB family hydrolase	-
K6975_RS03475 (K6975_03475)	-	711494..712306 (+)	813	WP_002936036.1	Cof-type HAD-IIB family hydrolase	-
K6975_RS03480 (K6975_03480)	pilA	712308..713582 (+)	1275	WP_012775180.1	signal recognition particle-docking protein FtsY	Machinery gene
K6975_RS03485 (K6975_03485)	-	713606..714163 (-)	558	WP_012027149.1	GNAT family N-acetyltransferase	-
K6975_RS03490 (K6975_03490)	-	714165..714839 (-)	675	WP_012027148.1	DNA alkylation repair protein	-
K6975_RS03495 (K6975_03495)	zwf	715039..716526 (-)	1488	WP_012027147.1	glucose-6-phosphate dehydrogenase	-
K6975_RS03500 (K6975_03500)	-	716605..717420 (-)	816	WP_012027146.1	TIGR03943 family putative permease subunit	-
K6975_RS03505 (K6975_03505)	-	717417..718322 (-)	906	WP_012027145.1	permease	-
K6975_RS03510 (K6975_03510)	-	718324..718470 (-)	147	WP_012027144.1	SPJ_0845 family protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 47099.51 Da
• Isoelectric Point: 4.4431

>NTDB_id=526565 K6975_RS03480 WP_012775180.1 712308..713582(+) (pilA) [Streptococcus suis strain Transconjugant cSS389]
MGLFDRLFGQKKQEEQVALVEEVEREQSASSEDTVTTEVESATQEMEKFQSEVAETELTAEQEAQKQRTLDMMAQYYAAK
EAAAARVKEAQEQGFDPAIQTKVKEEPVEEVAPVGQESEQDKYQRTLKKTRTGFGARLNEFFANFRSVDEEFFEELEEML
ILSDVGVQVASTLTEELRYEAKLQNAKKIDELRRVIIEKLVDIYEKDGQFSEQINFQDDLTVMLFVGVNGVGKTTSIGKL
AYKYKQAGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVVTGPEKSDPASVVFDGVKRAVAEGVDILMIDTAGRLQNKENL
MAELEKIGRIIKRTLPDAPHETLLALDASTGQNALSQAKEFAKITPLTGLVLTKLDGTAKGGVVLAIRQELDIPVKLIGF
GEKIDDIGEFKSEEFMRGLLEGLV

Nucleotide

• Length: 1275 bp

>NTDB_id=526565 K6975_RS03480 WP_012775180.1 712308..713582(+) (pilA) [Streptococcus suis strain Transconjugant cSS389]
ATGGGATTATTTGATCGATTATTTGGACAAAAAAAACAAGAGGAGCAAGTCGCTCTTGTTGAAGAAGTGGAAAGGGAGCA
GTCGGCTTCTAGCGAAGATACAGTAACTACTGAAGTTGAGTCAGCTACTCAAGAAATGGAAAAGTTCCAGTCTGAAGTAG
CAGAGACTGAATTGACAGCCGAACAAGAAGCTCAGAAACAACGGACCTTAGACATGATGGCTCAATATTATGCAGCCAAA
GAAGCCGCTGCGGCTCGAGTGAAGGAAGCGCAGGAACAAGGCTTTGACCCTGCTATTCAAACCAAGGTCAAGGAAGAGCC
TGTTGAGGAAGTTGCTCCAGTAGGGCAAGAAAGTGAACAGGACAAGTACCAGCGTACCTTGAAAAAGACGCGTACAGGAT
TTGGGGCAAGGCTCAATGAATTCTTTGCCAATTTCCGTTCGGTTGATGAAGAATTTTTCGAAGAGTTGGAAGAAATGCTG
ATTTTGTCAGACGTAGGTGTGCAAGTTGCTTCTACGCTGACAGAGGAGCTCCGCTATGAAGCCAAGCTACAAAATGCCAA
GAAGATAGATGAACTCCGTCGTGTTATCATCGAAAAATTGGTGGATATTTACGAAAAAGACGGTCAATTCAGTGAGCAAA
TCAATTTCCAAGATGATTTGACAGTCATGCTCTTTGTCGGTGTCAACGGTGTTGGGAAGACGACGTCTATCGGTAAGTTA
GCCTACAAGTACAAGCAAGCTGGCAAGAAGGTCATGTTGGTCGCAGCGGACACCTTCCGTGCGGGTGCGGTAGCCCAGCT
GGTCGAGTGGGGTCGCCGTGTCGATGTGCCAGTAGTCACAGGACCTGAAAAGTCAGACCCAGCTAGTGTGGTTTTTGATG
GGGTAAAACGTGCCGTGGCAGAAGGCGTGGATATTCTCATGATTGATACAGCAGGTCGCTTGCAAAATAAAGAAAACCTC
ATGGCAGAGCTGGAAAAAATCGGTCGCATCATCAAACGGACCCTACCTGATGCACCGCATGAAACCCTCTTAGCACTGGA
TGCCTCCACAGGTCAAAACGCCCTCAGTCAAGCCAAGGAATTTGCAAAAATTACTCCATTGACTGGGCTAGTCTTGACCA
AGCTAGACGGTACAGCCAAGGGTGGTGTCGTTCTTGCCATCCGTCAGGAACTGGATATACCAGTTAAGCTAATTGGTTTC
GGTGAGAAAATCGATGACATCGGTGAATTCAAATCCGAAGAATTCATGCGTGGGCTATTGGAAGGATTGGTATAG

Domains

Predicted by InterProScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (134-200)

3D structure

• AlphaFold DB: A0A0H3MUX4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	36.322	100	0.373