Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DMB76_RS04105 Genome accession   NZ_CP068029
Coordinates   870069..870785 (-) Length   238 a.a.
NCBI ID   WP_115312976.1    Uniprot ID   A0A380H0W7
Organism   Staphylococcus saccharolyticus strain 13T0028     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 865069..875785
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DMB76_RS04085 (DMB76_004085) - 865481..865707 (+) 227 Protein_826 sulfurtransferase TusA family protein -
  DMB76_RS04090 (DMB76_004090) - 865882..867120 (+) 1239 Protein_827 ammonium transporter -
  DMB76_RS04095 (DMB76_004095) - 867256..868209 (+) 954 Protein_828 LacI family DNA-binding transcriptional regulator -
  DMB76_RS04100 (DMB76_004100) - 868475..869950 (+) 1476 WP_115312975.1 sucrose-6-phosphate hydrolase -
  DMB76_RS04105 (DMB76_004105) agrA 870069..870785 (-) 717 WP_115312976.1 quorum-sensing response regulator AgrA Regulator
  DMB76_RS04110 (DMB76_004110) agrC 870802..872091 (-) 1290 WP_115312977.1 quorum-sensing sensor histidine kinase AgrC -
  DMB76_RS04115 (DMB76_004115) agrD 872118..872258 (-) 141 WP_115312978.1 cyclic lactone autoinducer peptide AgrD -
  DMB76_RS04120 (DMB76_004120) - 872242..872826 (-) 585 WP_115312979.1 accessory gene regulator AgrB -
  DMB76_RS04125 (DMB76_004125) hld 873139..873219 (+) 81 WP_115312980.1 delta-hemolysin -
  DMB76_RS04130 (DMB76_004130) - 873594..874378 (-) 785 Protein_835 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.03 Da        Isoelectric Point: 6.3014

>NTDB_id=526368 DMB76_RS04105 WP_115312976.1 870069..870785(-) (agrA) [Staphylococcus saccharolyticus strain 13T0028]
MKIFVCEDDPRQRENIVSIIKNYIMIEEKPMELTLATNDPYEVLKQSKEMNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNIDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLISHLDNRQIEFYGNLKELAQLDNRFFRCHNSFVVNRHNIESIDSKERIVYFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=526368 DMB76_RS04105 WP_115312976.1 870069..870785(-) (agrA) [Staphylococcus saccharolyticus strain 13T0028]
ATGAAAATATTCGTTTGCGAAGATGATCCAAGACAAAGAGAGAACATTGTTTCAATTATAAAAAACTATATTATGATTGA
AGAAAAACCTATGGAATTGACTCTCGCAACTAATGATCCTTATGAGGTTCTAAAACAATCCAAAGAAATGAATGACATCG
GTTGTTATTTCCTTGATATTCAATTAGAAGCTGATATGAATGGTATTAAACTTGCCAGCGAAATTCGTAAACATGATCCT
GTAGGCAATATTATATTTGTGACAAGTCATAGTGAACTCACTTATTTAACGTTTGTATATAAAGTCGCTGCAATGGACTT
TATTTTTAAAGATGATCCATCAGAACTTAAAATGAGAATTATTGATTGTCTTGAAACAGCACATACACGTTTAAAATTAC
TATCTAAAGAAAGTAATATAGACACCATTGAGTTGAAACGTGGTAGCAATTCGGTATATGTACAATATGACGATATCATG
TTTTTTGAATCATCTACAAAGTCACATCGTCTGATTTCACATCTTGATAATCGTCAAATTGAGTTTTACGGAAATTTAAA
AGAATTGGCACAACTTGATAATCGCTTCTTTAGATGTCATAACAGCTTTGTAGTTAATAGACATAATATCGAGTCTATTG
ATTCTAAAGAACGTATCGTTTATTTTAAAAATGGAGAACATTGTTTCGCGTCCGTACGTAATGTTAAAAAAATTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380H0W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878