Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   DMB76_RS01370 Genome accession   NZ_CP068029
Coordinates   318230..318895 (+) Length   221 a.a.
NCBI ID   WP_115312592.1    Uniprot ID   A0A380GXG4
Organism   Staphylococcus saccharolyticus strain 13T0028     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 295765..325253 318230..318895 within 0


Gene organization within MGE regions


Location: 295765..325253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DMB76_RS12160 - 296545..297072 (+) 528 WP_232619703.1 poly-gamma-glutamate hydrolase family protein -
  DMB76_RS12165 - 297066..297404 (+) 339 WP_232619702.1 poly-gamma-glutamate hydrolase family protein -
  DMB76_RS01270 (DMB76_001270) - 297696..297797 (+) 102 WP_115312574.1 SE2200 family small protein -
  DMB76_RS01275 (DMB76_001275) - 297992..299461 (+) 1470 Protein_269 NAD(P)H-binding protein -
  DMB76_RS01280 (DMB76_001280) - 299849..300511 (+) 663 WP_115312576.1 Wzz/FepE/Etk N-terminal domain-containing protein -
  DMB76_RS01285 (DMB76_001285) - 300524..301216 (+) 693 WP_115312577.1 polysaccharide biosynthesis tyrosine autokinase -
  DMB76_RS01290 (DMB76_001290) - 301219..301986 (+) 768 WP_115312578.1 tyrosine-protein phosphatase -
  DMB76_RS01295 (DMB76_001295) - 302014..303825 (+) 1812 WP_115312579.1 polysaccharide biosynthesis protein -
  DMB76_RS01300 (DMB76_001300) - 303827..305200 (+) 1374 WP_115312580.1 hypothetical protein -
  DMB76_RS01305 (DMB76_001305) wzx 305204..306574 (+) 1371 WP_115312581.1 O-unit flippase-like protein -
  DMB76_RS01310 (DMB76_001310) - 306604..307788 (+) 1185 WP_115312582.1 glycosyltransferase -
  DMB76_RS01315 (DMB76_001315) - 307791..308669 (+) 879 WP_115312583.1 glycosyltransferase family 2 protein -
  DMB76_RS01320 (DMB76_001320) - 308673..309176 (+) 504 WP_115312584.1 acyltransferase -
  DMB76_RS01325 (DMB76_001325) - 309222..310223 (+) 1002 WP_115312585.1 NAD-dependent epimerase -
  DMB76_RS01330 (DMB76_001330) - 310238..311512 (+) 1275 WP_115312586.1 nucleotide sugar dehydrogenase -
  DMB76_RS01335 (DMB76_001335) - 311530..312666 (+) 1137 WP_238994482.1 glycosyltransferase family 4 protein -
  DMB76_RS01340 (DMB76_001340) - 312683..313279 (+) 597 WP_115312588.1 sugar transferase -
  DMB76_RS01345 (DMB76_001345) - 313276..313896 (+) 621 WP_115312589.1 acetyltransferase -
  DMB76_RS01350 (DMB76_001350) - 313902..315044 (+) 1143 WP_269780153.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
  DMB76_RS01355 (DMB76_001355) - 315048..315989 (+) 942 WP_130549567.1 LCP family protein -
  DMB76_RS01360 (DMB76_001360) - 316241..317725 (-) 1485 WP_130522109.1 alkaline phosphatase -
  DMB76_RS01365 (DMB76_001365) - 318047..318202 (+) 156 WP_165417837.1 hypothetical protein -
  DMB76_RS01370 (DMB76_001370) braR 318230..318895 (+) 666 WP_115312592.1 response regulator transcription factor Regulator
  DMB76_RS01375 (DMB76_001375) braS 318901..319794 (+) 894 WP_115312593.1 sensor histidine kinase Regulator
  DMB76_RS01380 (DMB76_001380) - 319905..320654 (+) 750 WP_115312594.1 ABC transporter ATP-binding protein -
  DMB76_RS01385 (DMB76_001385) - 320656..322668 (+) 2013 WP_115312595.1 FtsX-like permease family protein -
  DMB76_RS01390 (DMB76_001390) - 322775..323184 (+) 410 Protein_292 DUF4064 domain-containing protein -
  DMB76_RS01395 (DMB76_001395) - 323661..325253 (+) 1593 WP_115312597.1 solute:sodium symporter family transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25544.57 Da        Isoelectric Point: 4.4378

>NTDB_id=526363 DMB76_RS01370 WP_115312592.1 318230..318895(+) (braR) [Staphylococcus saccharolyticus strain 13T0028]
MKILIVEDDLVIAESLENELSKWNYEVVVVDNFEQIMEDFHEVAPQLVLLDINLPTLNGFHWCQEMRKESNVPIMFISSR
IDNMDQIMAIQMGGDGFIEKPFNLSLTVAKIQALLRRTYDLSLSRNELEVKGCKLILDEAKIINGDDTVQLSLTELQILK
LLFQNEDKYVNRTALIEKCWESENFIDDNTLAVNMTRLRKKLLSIGLTDFIETKKNVGYRV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=526363 DMB76_RS01370 WP_115312592.1 318230..318895(+) (braR) [Staphylococcus saccharolyticus strain 13T0028]
ATGAAGATTCTCATAGTAGAAGATGACCTAGTGATTGCAGAAAGCTTAGAGAATGAGCTTTCTAAATGGAATTATGAGGT
AGTTGTTGTAGACAATTTCGAGCAAATTATGGAAGATTTTCATGAAGTTGCACCTCAACTTGTTTTGTTGGACATTAATT
TGCCGACACTCAATGGTTTTCATTGGTGTCAGGAAATGCGTAAAGAATCTAATGTTCCAATTATGTTTATTAGTTCTCGT
ATAGACAATATGGATCAAATTATGGCTATTCAAATGGGTGGCGATGGTTTTATTGAGAAACCTTTCAATTTATCTTTAAC
TGTTGCTAAAATTCAAGCACTTTTACGTCGTACTTATGATTTATCTCTATCTAGAAACGAACTTGAAGTAAAAGGGTGCA
AGCTAATCTTAGATGAAGCAAAAATTATAAATGGTGATGACACTGTGCAGCTATCTCTGACAGAGCTGCAGATTTTAAAG
CTATTGTTTCAAAATGAGGATAAATATGTGAATCGTACAGCGTTAATTGAAAAATGTTGGGAATCTGAAAATTTCATTGA
CGATAATACACTTGCTGTAAATATGACTCGATTGCGTAAAAAACTGCTTTCCATAGGATTAACTGACTTTATTGAAACTA
AGAAAAATGTTGGATACAGGGTTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380GXG4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

80.09

100

0.801