Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   K6131_RS21540 Genome accession   NZ_CP082047
Coordinates   4456831..4459686 (-) Length   951 a.a.
NCBI ID   WP_302361781.1    Uniprot ID   -
Organism   Escherichia coli strain MS21199     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4451831..4464686
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6131_RS21520 (K6131_21370) - 4452925..4454745 (-) 1821 WP_001540429.1 ATP-binding protein -
  K6131_RS21525 (K6131_21375) aphA 4455022..4455735 (+) 714 WP_001226933.1 acid phosphatase AphA -
  K6131_RS21530 (K6131_21380) yjbQ 4455846..4456262 (+) 417 WP_000270369.1 secondary thiamine-phosphate synthase enzyme YjbQ -
  K6131_RS21535 (K6131_21385) yjbR 4456266..4456622 (+) 357 WP_000155657.1 MmcQ/YjbR family DNA-binding protein -
  K6131_RS21540 (K6131_21390) uvrA 4456831..4459686 (-) 2856 WP_302361781.1 excinuclease ABC subunit UvrA Machinery gene
  K6131_RS21545 (K6131_21395) ssb 4459941..4460477 (+) 537 WP_000168305.1 single-stranded DNA-binding protein SSB1 Machinery gene
  K6131_RS21550 (K6131_21400) yjcB 4460576..4460857 (-) 282 WP_001296643.1 YjcB family protein -
  K6131_RS21555 (K6131_21405) pdeC 4461286..4462839 (+) 1554 WP_001540433.1 c-di-GMP phosphodiesterase PdeC -
  K6131_RS21560 (K6131_21410) soxS 4462875..4463198 (-) 324 WP_000019358.1 superoxide response transcriptional regulator SoxS -
  K6131_RS21565 (K6131_21415) soxR 4463284..4463748 (+) 465 WP_000412431.1 redox-sensitive transcriptional activator SoxR -

Sequence

Protein


Download         Length: 951 a.a.        Molecular weight: 105139.96 Da        Isoelectric Point: 6.5723

>NTDB_id=524901 K6131_RS21540 WP_302361781.1 4456831..4459686(-) (uvrA) [Escherichia coli strain MS21199]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLYARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSTNVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALAREFFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGHTLYILDEPTTGLHFADIQ
QLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide


Download         Length: 2856 bp        

>NTDB_id=524901 K6131_RS21540 WP_302361781.1 4456831..4459686(-) (uvrA) [Escherichia coli strain MS21199]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTTAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAGAAGCCGGACGTCGACCATATTGAAGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGCTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTCTGCTGTACGCTCGCGTTGGTGAGCCACGCTGCCCGGACCACGATGTACCGCTGGCGGCGCAAACCGTCAGTC
AGATGGTGGATAACGTGTTGTCCCAGCCGGAAGGCAAGCGTCTGATGCTGCTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAGAACCTGGCAAGCCAAGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAATTGCAAAAGAAACATACCATTGAAGTGGTGGTTGATCGCTTCAAAGTGCGTGACGATCTTA
CCCAACGTCTTGCCGAGTCGTTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTGGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTGTTCTCCGCCAACTTTGCCTGCCCGATTTGCGGTTACAGTATGCGCGAGCTGGAACCTCGCCT
GTTTTCATTTAACAACCCGGCGGGAGCCTGCCCGACCTGTGACGGTCTTGGCGTACAGCAATATTTCGATCCTGACCGCG
TGATCCAGAATCCGGAATTGTCGCTGGCTGGCGGTGCGATCCGTGGCTGGGATCGCCGCAACTTCTATTATTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCACGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAATATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGTGCGGTACGTGAAGAATTAGCCAAGTTT
ATCAGCAATCGTCCGTGCGCCAGCTGCGAAGGAACCCGTCTGCGTCGGGAAGCACGCCACGTGTATGTCGAGAATACGCC
GCTGCCCGCCATCTCCGACATGAGCATCGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGGGCGA
AGATTGCAGAAAAAATCCTTAAAGAGATCGGCGATCGTCTGAAATTCCTCGTTAACGTCGGCCTGAATTACCTGACACTT
TCCCGCTCGGCAGAGACACTTTCCGGCGGTGAAGCCCAGCGTATTCGTCTGGCGAGCCAGATTGGTGCAGGCCTGGTTGG
CGTGATGTACGTGCTGGATGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGTTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCTGATCATGTGATCGATATC
GGTCCGGGTGCGGGTGTTCACGGCGGTGAAGTGGTCGCGGAAGGTCCACTGGAAGCGATTATGGCGGTGCCTGAGTCGTT
GACCGGGCAGTACATGAGCGGTAAACGCAAGATTGAGGTGCCGAAGAAGCGCGTTCCGGCAAATCCGGAAAAAGTGCTGA
AGCTGACAGGCGCACGCGGCAACAACCTGAAAGACGTGACGCTGACGCTGCCGGTGGGTCTGTTTACTTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACGCTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGTGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGACTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACACCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGCGGCTATACGCCAGGACGTTTCAGCTTTAACGTCCGTGGCGGACGCTGCGAGGCCTGTCAGGGCGACGG
CGTGATCAAAGTGGAGATGCACTTCCTGCCGGACATTTACGTACCGTGCGACCAGTGCAAAGGCAAACGCTATAACCGTG
AAACGCTGGAGATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCGCGTGAGTTCTTTGATGCGGTGCCAGCTCTGGCGCGTAAGCTGCAAACGCTGATGGATGT
TGGCCTGACGTACATTCGCCTCGGGCAGTCCGCAACCACACTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTG
AGCTGTCAAAACGCGGCACCGGGCATACGCTGTATATTCTCGACGAGCCGACCACCGGTCTGCACTTCGCCGATATTCAG
CAACTGCTCGACGTACTGCATAAACTGCGCGATCAGGGCAATACCATTGTGGTAATTGAGCACAATCTCGACGTGATCAA
AACCGCTGACTGGATTGTCGACCTGGGACCGGAAGGCGGCAGTGGGGGCGGCGAAATCCTCGTCTCCGGTACGCCAGAAA
CCGTCGCAGAGTGCGAAGCTTCGCATACGGCGCGCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(817-871)

UvrA DNA-binding domain (UvrA_DNA-bind)

(290-399)

UvrA interaction domain (UvrA_inter)

(130-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.023

100

0.572
  uvrA Streptococcus pneumoniae TIGR4

57.023

100

0.572
  uvrA Streptococcus pneumoniae D39

57.023

100

0.572