Detailed information NTG0524409

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: I6I26_RS04630
• Genome accession: NZ_CP067014
• Coordinates: 951255..952298 (+)
• Length: 347 a.a.
• NCBI ID: WP_017637854.1
• Uniprot ID: A0A654BBJ5
• Organism: Staphylococcus pasteuri strain FDAARGOS_1069
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 946255..957298

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I26_RS04605 (I6I26_04605)	-	946987..947712 (+)	726	WP_126567677.1	type 1 glutamine amidotransferase	-
I6I26_RS04610 (I6I26_04610)	-	948098..949084 (-)	987	WP_029056008.1	aromatic acid exporter family protein	-
I6I26_RS04615 (I6I26_04615)	map	949250..950005 (+)	756	WP_017637857.1	type I methionyl aminopeptidase	-
I6I26_RS04620 (I6I26_04620)	-	950156..950542 (+)	387	WP_017637856.1	DUF2543 family protein	-
I6I26_RS04625 (I6I26_04625)	liaF	950557..951258 (+)	702	WP_126567676.1	cell wall-active antibiotics response protein LiaF	-
I6I26_RS04630 (I6I26_04630)	vraS	951255..952298 (+)	1044	WP_017637854.1	sensor histidine kinase	Regulator
I6I26_RS04635 (I6I26_04635)	vraR	952288..952917 (+)	630	WP_017637853.1	two-component system response regulator VraR	Regulator
I6I26_RS04640 (I6I26_04640)	-	953008..954246 (-)	1239	WP_017637852.1	YihY/virulence factor BrkB family protein	-
I6I26_RS04645 (I6I26_04645)	-	954536..954820 (-)	285	WP_017637851.1	hypothetical protein	-
I6I26_RS04650 (I6I26_04650)	-	954825..955289 (-)	465	WP_017637850.1	low molecular weight protein-tyrosine-phosphatase	-
I6I26_RS04655 (I6I26_04655)	-	955451..955633 (+)	183	WP_037555624.1	DUF1128 domain-containing protein	-
I6I26_RS04660 (I6I26_04660)	-	955647..956888 (+)	1242	WP_046467434.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40047.46 Da
• Isoelectric Point: 6.2449

>NTDB_id=524409 I6I26_RS04630 WP_017637854.1 951255..952298(+) (vraS) [Staphylococcus pasteuri strain FDAARGOS_1069]
MNHYIRAIGSMLILTYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWINS
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=524409 I6I26_RS04630 WP_017637854.1 951255..952298(+) (vraS) [Staphylococcus pasteuri strain FDAARGOS_1069]
ATGAATCACTATATAAGAGCAATAGGCTCTATGCTCATTTTAACGTATAGTATGTTAACCGCATTTTTATTTATTGATAA
AGTATTTGTTAACATCATCTATTTTCAAGGTATGTTCTATACACAGATTTTTGGCATACCTGTATTCTTATTTTTAAATA
TCATAGTGATATTATTATGTATCATTGTAGGCTCTGTTTTAGCTTATAAAATTAATCAACAGAATGACTGGATTAATTCT
CAAATAGAACGATCTATTGAAGGTGAAACAGTTGGTATCAATGACCAAAATATAGAATTATATAGTGAAACACTGGAAAT
ATATCATACACTTGTACCATTAAATCAGGAATTACATCGATTAAGAATGAAAACACAAAACTTAACTAATGAAAACTACA
ACATGAACGATGTAAAAGTTAAAAAGATTATTGAAGACGAAAGACAACGTCTAGCTAGAGAATTACATGACTCAGTAAGT
CAACAATTATTCGCTGCGAGTATGATGTTATCAGCGATTAAAGAAACTAAATTAGAACCCCCATTAGACCAACAAATTCC
AGTTTTAGAGAAAATGGTACAAGATTCACAACTTGAAATGAGAGCTTTATTATTACATTTACGACCTCTAGGGTTGAAAG
ATAAGTCCTTAGGTGAAGGAATTAAAGATTTAGTTATAGATCTTCAAAAGAAAGTTCCGATGAAAGTTGTACATGAAATA
CAAGAATTTAAAGTTCCTAAAGGTATCGAAGATCATTTATTTAGAATTACTCAAGAAGCTATTTCAAATACATTAAGACA
TTCTAATGGCACTAGAGTGACGGTTGAACTATTTAATAAACAAGATTATTTATTATTACGTATACAAGATAATGGTAAAG
GCTTTAATGTAGATGAAAAATTGGAACAAAGCTATGGTTTAAAAAATATGAGAGAACGTGCATTAGAAATTGGTGCTACA
TTCCATATCGTTTCGTTACCTGATTCCGGAACACGTATAGAAGTTAAAGCCCCATTGAACAAGGAGGATTCTTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A654BBJ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.524	100	0.945