Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   U471_RS06690 Genome accession   NC_022653
Coordinates   1303059..1305155 (-) Length   698 a.a.
NCBI ID   WP_012117416.1    Uniprot ID   A7Z3Y3
Organism   Bacillus amyloliquefaciens CC178     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1298059..1310155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U471_RS06665 (U471_13640) - 1298648..1298908 (+) 261 WP_003154690.1 aspartyl-phosphate phosphatase Spo0E family protein -
  U471_RS06670 (U471_13650) - 1299119..1300636 (-) 1518 WP_046559543.1 ATP-binding protein -
  U471_RS06675 (U471_13660) - 1300835..1301281 (+) 447 WP_007408463.1 MarR family winged helix-turn-helix transcriptional regulator -
  U471_RS06680 (U471_13680) motB 1301317..1302102 (-) 786 WP_003154685.1 flagellar motor protein MotB -
  U471_RS06685 (U471_13690) motA 1302074..1302889 (-) 816 WP_007408461.1 flagellar motor stator protein MotA -
  U471_RS06690 (U471_13700) clpE 1303059..1305155 (-) 2097 WP_012117416.1 ATP-dependent protease ATP-binding subunit ClpE Regulator
  U471_RS06700 (U471_13720) - 1305557..1306594 (+) 1038 WP_012117417.1 membrane protein -
  U471_RS06705 (U471_13730) - 1306692..1307813 (+) 1122 WP_012117418.1 hypothetical protein -
  U471_RS06710 (U471_13740) queC 1308063..1308722 (+) 660 WP_003154679.1 7-cyano-7-deazaguanine synthase QueC -
  U471_RS06715 (U471_13750) queD 1308783..1309166 (+) 384 WP_229024199.1 6-carboxytetrahydropterin synthase QueD -
  U471_RS06720 (U471_13760) queE 1309159..1309890 (+) 732 WP_003154676.1 7-carboxy-7-deazaguanine synthase QueE -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 77768.84 Da        Isoelectric Point: 5.4325

>NTDB_id=52336 U471_RS06690 WP_012117416.1 1303059..1305155(-) (clpE) [Bacillus amyloliquefaciens CC178]
MRCQHCQKNEATIRLNMQVNSIQKQFVLCETCYTELTRKPAMSMGPQSFGFPFEQGFAPNQNKQQAGPEKGLLDELAQNV
TNGAKAGLIDPVIGRDHEVARVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIAEGDVPNKLKNKELYLLDVASLVAN
TGIRGQFEERMKQLMNELKERKNVILFIDEIHLLVGAGSAEGSMDAGNILKPALARGELQVIGATTLKEYRQIEKDAALE
RRFQPVMVHEPTIEQAISILEGIKDKYEKYHGVTFSNEAINACVTLSSRYIQDRHLPDKAIDLLDEAGSKANLELDTVNE
EDAAERLKAIDAEKTKALHEENYELAAKLRDEEAALEKQLAHETPASSPEIGAEHIQAIIEQKTGIPVGKLQADEQVKMK
ELEEHLHQRVIGQEKAVKKVAKAVRRSRAGLKSKNRPVGSFLFVGPTGVGKTELSKTLADELFGTKDSIIRLDMSEYMEK
HAVSKIIGSPPGYVGHDEAGQLTEKVRRNPYSIVLLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVLIMTSNA
GTGEKQVKVGFQSEESVLEEQTLIDSLSAFFKPEFLNRFDSIIEFQSLKKEHLVKIVSLLLTELEDTLKERGISLSVTDE
AKEKIAEIGYHPAFGARPLRRTIQELIEDEMTDLLLDNNEIKAFHVVMEEDGIKVRAQ

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=52336 U471_RS06690 WP_012117416.1 1303059..1305155(-) (clpE) [Bacillus amyloliquefaciens CC178]
ATGCGTTGTCAACATTGTCAGAAAAACGAGGCGACGATTCGCCTGAACATGCAAGTCAATTCCATTCAAAAACAATTCGT
TTTATGTGAAACATGTTATACAGAATTAACCCGAAAACCGGCTATGAGCATGGGGCCGCAATCATTCGGATTCCCGTTTG
AGCAAGGTTTCGCTCCCAATCAAAATAAACAGCAGGCCGGCCCTGAAAAAGGCCTGCTCGACGAGCTCGCTCAAAACGTC
ACAAACGGCGCAAAAGCAGGTCTGATTGACCCTGTGATCGGCCGCGATCATGAAGTGGCGCGCGTAATTGAAATTTTGAA
CCGCCGGAATAAAAACAATCCGGTGCTGATCGGTGAGCCGGGCGTCGGTAAAACGGCTATTGCAGAAGGCCTCGCGCTTA
AAATCGCTGAAGGCGATGTGCCGAACAAATTGAAAAACAAAGAGCTTTACCTGCTTGACGTCGCTTCTCTCGTCGCCAAT
ACAGGGATCAGAGGCCAGTTTGAAGAAAGAATGAAACAATTAATGAACGAATTAAAAGAACGGAAAAACGTCATCTTGTT
CATTGACGAGATTCACCTTCTTGTAGGCGCCGGCTCTGCCGAGGGATCAATGGATGCCGGGAACATCCTGAAACCGGCGC
TTGCCAGAGGCGAGCTGCAGGTCATCGGGGCGACAACGCTGAAAGAGTACCGCCAGATTGAAAAAGATGCGGCGCTTGAA
AGACGCTTCCAGCCTGTCATGGTTCACGAGCCTACAATAGAACAAGCCATCAGCATTCTGGAAGGCATTAAAGATAAATA
TGAGAAATACCACGGCGTCACATTCAGCAATGAAGCGATAAATGCCTGTGTTACGCTTTCATCCCGTTACATTCAGGACC
GCCACCTGCCGGATAAAGCGATCGACTTATTAGATGAAGCCGGCTCTAAGGCGAACCTGGAGCTTGATACCGTAAATGAA
GAAGATGCGGCTGAGAGACTCAAAGCAATTGACGCGGAGAAAACAAAAGCGCTTCATGAAGAAAATTATGAGCTTGCCGC
GAAACTGCGTGATGAAGAAGCGGCGTTGGAAAAGCAGCTGGCGCATGAAACACCGGCCTCTTCACCTGAAATCGGGGCGG
AGCATATTCAAGCCATCATTGAACAGAAAACAGGCATTCCGGTCGGAAAACTCCAGGCTGATGAACAAGTCAAAATGAAG
GAACTTGAAGAGCATCTTCATCAGCGCGTCATCGGTCAGGAAAAAGCCGTGAAAAAAGTGGCGAAAGCGGTCAGACGAAG
CCGCGCCGGCTTAAAATCCAAAAACAGACCTGTCGGCTCCTTCCTCTTTGTCGGACCGACCGGAGTCGGAAAAACCGAGT
TATCAAAGACACTCGCAGATGAACTGTTCGGTACAAAAGATTCCATTATCCGTCTCGATATGAGTGAATACATGGAAAAA
CACGCCGTATCAAAAATCATCGGTTCACCGCCGGGATATGTCGGACACGATGAAGCCGGTCAATTAACGGAAAAAGTGCG
CCGCAATCCGTACAGCATCGTGCTGCTCGATGAGATTGAAAAAGCCCACCCTGATGTCCAGCATATGTTTCTGCAGATTA
TGGAGGACGGCCGTCTGACAGACAGCCAGGGCAGAACGGTCAGCTTCAAAGATACCGTTTTGATTATGACAAGCAACGCT
GGAACCGGCGAAAAACAGGTGAAAGTCGGATTCCAATCTGAAGAGAGCGTCCTGGAAGAACAAACGCTGATTGATTCACT
GAGCGCGTTCTTCAAACCGGAGTTTTTAAACCGGTTTGACAGCATCATTGAATTCCAATCCCTGAAAAAAGAACATCTCG
TGAAAATCGTCAGCCTGCTTCTCACAGAGCTTGAAGACACATTAAAAGAGCGCGGCATCAGCCTGAGCGTAACGGACGAA
GCGAAAGAAAAAATCGCTGAAATCGGCTACCACCCAGCTTTCGGAGCACGCCCGCTCAGAAGAACCATCCAAGAATTGAT
CGAGGACGAAATGACAGATCTCTTATTGGATAACAACGAAATAAAAGCCTTCCATGTCGTAATGGAAGAGGACGGCATCA
AAGTCCGGGCACAATAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-679)

AAA lid domain (AAA_lid_9)

(252-351)

AAA domain (Cdc48 subfamily) (AAA_2)

(436-602)

ATPase family associated with various cellular activities (AAA) (AAA)

(115-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A7Z3Y3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

56.735

100

0.597
  clpC Lactococcus lactis subsp. cremoris KW2

56.54

100

0.595
  clpE Streptococcus pneumoniae Rx1

56.267

100

0.592
  clpE Streptococcus pneumoniae R6

56.267

100

0.592
  clpE Streptococcus pneumoniae D39

56.267

100

0.592
  clpE Streptococcus pneumoniae TIGR4

56.267

100

0.592
  clpC Bacillus subtilis subsp. subtilis str. 168

54.232

91.404

0.496
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.311

91.261

0.423
  clpC Streptococcus pneumoniae TIGR4

45.88

88.682

0.407
  clpC Streptococcus pneumoniae Rx1

45.88

88.682

0.407
  clpC Streptococcus pneumoniae D39

45.88

88.682

0.407
  clpC Streptococcus thermophilus LMD-9

45.381

88.395

0.401
  clpC Streptococcus thermophilus LMG 18311

44.733

88.395

0.395
  clpC Streptococcus mutans UA159

44.3

87.966

0.39

Multiple sequence alignment