Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | JG532_RS02475 | Genome accession | NZ_CP066748 |
| Coordinates | 507017..508141 (+) | Length | 374 a.a. |
| NCBI ID | WP_000228544.1 | Uniprot ID | A0A9P2PX49 |
| Organism | Escherichia coli O157:H7 strain ECP19-2498 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 481131..508141 | 507017..508141 | within | 0 |
Gene organization within MGE regions
Location: 481131..508141
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JG532_RS02260 (JG532_02260) | rpsL | 481131..481505 (+) | 375 | WP_000246815.1 | 30S ribosomal protein S12 | - |
| JG532_RS02265 (JG532_02265) | rpsG | 481602..482072 (+) | 471 | WP_001138043.1 | 30S ribosomal protein S7 | - |
| JG532_RS02270 (JG532_02270) | fusA | 482169..484283 (+) | 2115 | WP_000124700.1 | elongation factor G | - |
| JG532_RS02275 (JG532_02275) | tuf | 484354..485538 (+) | 1185 | WP_000031783.1 | elongation factor Tu | - |
| JG532_RS02280 (JG532_02280) | bfd | 485721..485915 (+) | 195 | WP_000289090.1 | bacterioferritin-associated ferredoxin | - |
| JG532_RS02285 (JG532_02285) | bfr | 485988..486464 (+) | 477 | WP_000675516.1 | bacterioferritin | - |
| JG532_RS02290 (JG532_02290) | - | 486461..486928 (-) | 468 | WP_000381746.1 | A24 family peptidase | - |
| JG532_RS02295 (JG532_02295) | rpsJ | 487307..487618 (+) | 312 | WP_001181004.1 | 30S ribosomal protein S10 | - |
| JG532_RS02300 (JG532_02300) | rplC | 487651..488280 (+) | 630 | WP_000579833.1 | 50S ribosomal protein L3 | - |
| JG532_RS02305 (JG532_02305) | rplD | 488291..488896 (+) | 606 | WP_000424395.1 | 50S ribosomal protein L4 | - |
| JG532_RS02310 (JG532_02310) | rplW | 488893..489195 (+) | 303 | WP_000617544.1 | 50S ribosomal protein L23 | - |
| JG532_RS02315 (JG532_02315) | rplB | 489213..490034 (+) | 822 | WP_000301864.1 | 50S ribosomal protein L2 | - |
| JG532_RS02320 (JG532_02320) | rpsS | 490051..490329 (+) | 279 | WP_001138117.1 | 30S ribosomal protein S19 | - |
| JG532_RS02325 (JG532_02325) | rplV | 490344..490676 (+) | 333 | WP_000447529.1 | 50S ribosomal protein L22 | - |
| JG532_RS02330 (JG532_02330) | rpsC | 490694..491395 (+) | 702 | WP_000529945.1 | 30S ribosomal protein S3 | - |
| JG532_RS02335 (JG532_02335) | rplP | 491408..491818 (+) | 411 | WP_000941212.1 | 50S ribosomal protein L16 | - |
| JG532_RS02340 (JG532_02340) | rpmC | 491818..492009 (+) | 192 | WP_000644741.1 | 50S ribosomal protein L29 | - |
| JG532_RS02345 (JG532_02345) | rpsQ | 492009..492263 (+) | 255 | WP_000130100.1 | 30S ribosomal protein S17 | - |
| JG532_RS02350 (JG532_02350) | rplN | 492428..492799 (+) | 372 | WP_000613955.1 | 50S ribosomal protein L14 | - |
| JG532_RS02355 (JG532_02355) | rplX | 492810..493124 (+) | 315 | WP_000729185.1 | 50S ribosomal protein L24 | - |
| JG532_RS02360 (JG532_02360) | rplE | 493139..493678 (+) | 540 | WP_001096200.1 | 50S ribosomal protein L5 | - |
| JG532_RS02365 (JG532_02365) | rpsN | 493693..493998 (+) | 306 | WP_001118930.1 | 30S ribosomal protein S14 | - |
| JG532_RS02370 (JG532_02370) | rpsH | 494032..494424 (+) | 393 | WP_000062611.1 | 30S ribosomal protein S8 | - |
| JG532_RS02375 (JG532_02375) | rplF | 494437..494970 (+) | 534 | WP_000091945.1 | 50S ribosomal protein L6 | - |
| JG532_RS02380 (JG532_02380) | rplR | 494980..495333 (+) | 354 | WP_000358960.1 | 50S ribosomal protein L18 | - |
| JG532_RS02385 (JG532_02385) | rpsE | 495348..495851 (+) | 504 | WP_000940121.1 | 30S ribosomal protein S5 | - |
| JG532_RS02390 (JG532_02390) | rpmD | 495855..496034 (+) | 180 | WP_001140433.1 | 50S ribosomal protein L30 | - |
| JG532_RS02395 (JG532_02395) | rplO | 496038..496472 (+) | 435 | WP_001238917.1 | 50S ribosomal protein L15 | - |
| JG532_RS02400 (JG532_02400) | secY | 496480..497811 (+) | 1332 | WP_001118861.1 | preprotein translocase subunit SecY | - |
| JG532_RS02405 (JG532_02405) | rpmJ | 497843..497959 (+) | 117 | WP_000868187.1 | 50S ribosomal protein L36 | - |
| JG532_RS02410 (JG532_02410) | rpsM | 498106..498462 (+) | 357 | WP_000090775.1 | 30S ribosomal protein S13 | - |
| JG532_RS02415 (JG532_02415) | rpsK | 498479..498868 (+) | 390 | WP_001029684.1 | 30S ribosomal protein S11 | - |
| JG532_RS02420 (JG532_02420) | rpsD | 498902..499522 (+) | 621 | WP_000135224.1 | 30S ribosomal protein S4 | - |
| JG532_RS02425 (JG532_02425) | rpoA | 499548..500537 (+) | 990 | WP_001162094.1 | DNA-directed RNA polymerase subunit alpha | - |
| JG532_RS02430 (JG532_02430) | rplQ | 500578..500961 (+) | 384 | WP_001216368.1 | 50S ribosomal protein L17 | - |
| JG532_RS02435 (JG532_02435) | yhdN | 501068..501436 (+) | 369 | WP_000266488.1 | DUF1992 domain-containing protein | - |
| JG532_RS02440 (JG532_02440) | zntR | 501447..501872 (+) | 426 | WP_000285607.1 | Zn(2+)-responsive transcriptional regulator | - |
| JG532_RS02445 (JG532_02445) | arfA | 501928..502146 (+) | 219 | WP_000092696.1 | alternative ribosome-rescue factor ArfA | - |
| JG532_RS02450 (JG532_02450) | mscL | 502143..502553 (-) | 411 | WP_000022442.1 | large-conductance mechanosensitive channel protein MscL | - |
| JG532_RS02455 (JG532_02455) | trkA | 502683..504059 (-) | 1377 | WP_000691382.1 | Trk system potassium transporter TrkA | - |
| JG532_RS02460 (JG532_02460) | rsmB | 504081..505370 (-) | 1290 | WP_001301795.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| JG532_RS02465 (JG532_02465) | fmt | 505416..506363 (-) | 948 | WP_000004459.1 | methionyl-tRNA formyltransferase | - |
| JG532_RS02470 (JG532_02470) | def | 506378..506887 (-) | 510 | WP_000114984.1 | peptide deformylase | - |
| JG532_RS02475 (JG532_02475) | dprA | 507017..508141 (+) | 1125 | WP_000228544.1 | DNA-protecting protein DprA | Machinery gene |
Sequence
Protein
Download Length: 374 a.a. Molecular weight: 41005.96 Da Isoelectric Point: 6.2655
>NTDB_id=522328 JG532_RS02475 WP_000228544.1 507017..508141(+) (dprA) [Escherichia coli O157:H7 strain ECP19-2498]
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
Nucleotide
Download Length: 1125 bp
>NTDB_id=522328 JG532_RS02475 WP_000228544.1 507017..508141(+) (dprA) [Escherichia coli O157:H7 strain ECP19-2498]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Vibrio campbellii strain DS40M4 |
48.78 |
98.663 |
0.481 |
| dprA | Glaesserella parasuis strain SC1401 |
45.401 |
90.107 |
0.409 |
| dprA | Vibrio cholerae strain A1552 |
49.355 |
82.888 |
0.409 |
| dprA | Haemophilus influenzae Rd KW20 |
44.214 |
90.107 |
0.398 |
| dprA | Legionella pneumophila strain ERS1305867 |
44.545 |
88.235 |
0.393 |