Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   HLV54_RS07570 Genome accession   NZ_CP080770
Coordinates   1579546..1580253 (+) Length   235 a.a.
NCBI ID   WP_000094093.1    Uniprot ID   A0A1D4DWM6
Organism   Staphylococcus aureus strain HL23187     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1574546..1585253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HLV54_RS07495 (HLV54_001499) - 1574848..1575108 (-) 261 WP_001556704.1 DUF1108 family protein -
  HLV54_RS07500 (HLV54_001500) - 1575113..1575430 (-) 318 WP_000829610.1 hypothetical protein -
  HLV54_RS07505 (HLV54_001501) - 1575519..1575680 (-) 162 WP_001285954.1 DUF1270 domain-containing protein -
  HLV54_RS07510 (HLV54_001502) - 1575692..1575955 (-) 264 WP_001124198.1 helix-turn-helix domain-containing protein -
  HLV54_RS14240 - 1576104..1576203 (-) 100 Protein_1479 hypothetical protein -
  HLV54_RS07520 (HLV54_001504) - 1576200..1576526 (-) 327 WP_001025595.1 hypothetical protein -
  HLV54_RS14245 - 1576581..1576736 (+) 156 Protein_1481 hypothetical protein -
  HLV54_RS07530 (HLV54_001506) - 1576760..1577020 (-) 261 WP_000435343.1 hypothetical protein -
  HLV54_RS07535 (HLV54_001507) - 1577033..1577785 (-) 753 WP_001148617.1 phage antirepressor KilAC domain-containing protein -
  HLV54_RS07540 (HLV54_001508) - 1577846..1578073 (+) 228 WP_000801108.1 hypothetical protein -
  HLV54_RS07545 (HLV54_001509) - 1578075..1578266 (-) 192 WP_000502678.1 hypothetical protein -
  HLV54_RS07550 (HLV54_001510) - 1578323..1578532 (+) 210 WP_000772137.1 hypothetical protein -
  HLV54_RS07555 (HLV54_001511) - 1578525..1578665 (-) 141 WP_000939495.1 hypothetical protein -
  HLV54_RS07560 (HLV54_001512) - 1578680..1579123 (-) 444 WP_000435346.1 hypothetical protein -
  HLV54_RS07565 (HLV54_001513) - 1579136..1579375 (-) 240 WP_000548578.1 helix-turn-helix transcriptional regulator -
  HLV54_RS07570 (HLV54_001514) irvR 1579546..1580253 (+) 708 WP_000094093.1 XRE family transcriptional regulator Regulator
  HLV54_RS07575 (HLV54_001515) - 1580265..1580420 (+) 156 WP_001049399.1 hypothetical protein -
  HLV54_RS07580 (HLV54_001516) - 1580407..1580592 (+) 186 WP_001089804.1 hypothetical protein -
  HLV54_RS07585 (HLV54_001517) - 1580792..1580974 (+) 183 WP_000705240.1 hypothetical protein -
  HLV54_RS07590 (HLV54_001518) - 1581010..1581156 (+) 147 WP_001013104.1 hypothetical protein -
  HLV54_RS07595 (HLV54_001519) - 1581153..1581767 (-) 615 WP_000191466.1 hypothetical protein -
  HLV54_RS07600 (HLV54_001520) - 1581893..1583098 (+) 1206 WP_000264751.1 site-specific integrase -
  HLV54_RS07605 (HLV54_001521) - 1583141..1585168 (-) 2028 WP_001838630.1 hypothetical protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26769.35 Da        Isoelectric Point: 5.4082

>NTDB_id=521386 HLV54_RS07570 WP_000094093.1 1579546..1580253(+) (irvR) [Staphylococcus aureus strain HL23187]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=521386 HLV54_RS07570 WP_000094093.1 1579546..1580253(+) (irvR) [Staphylococcus aureus strain HL23187]
ATGAGTTCATTTTCTTCGAATTTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTTAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTATCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(123-234)

Helix-turn-helix (HTH_3)

(8-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1D4DWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

30.769

100

0.374