Detailed information NTG0520974

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: JFL57_RS03505
• Genome accession: NZ_CP066565
• Coordinates: 767670..768803 (-)
• Length: 377 a.a.
• NCBI ID: WP_198987017.1
• Uniprot ID: -
• Organism: Histophilus somni strain ASc-MMNZ-VFA-076
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 762670..773803

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JFL57_RS03485 (JFL57_03485)	galU	764048..764935 (+)	888	WP_075293726.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
JFL57_RS03490 (JFL57_03490)	-	764983..765846 (-)	864	WP_075293727.1	Dam family site-specific DNA-(adenine-N6)-methyltransferase	-
JFL57_RS03495 (JFL57_03495)	aroB	765853..766941 (-)	1089	WP_075293728.1	3-dehydroquinate synthase	-
JFL57_RS03500 (JFL57_03500)	aroK	766961..767488 (-)	528	Protein_670	shikimate kinase AroK	-
JFL57_RS03505 (JFL57_03505)	comE	767670..768803 (-)	1134	WP_198987017.1	type IV pilus secretin PilQ	Machinery gene
JFL57_RS03510 (JFL57_03510)	-	768819..769316 (-)	498	WP_011609266.1	hypothetical protein	-
JFL57_RS03515 (JFL57_03515)	-	769320..769859 (-)	540	WP_012340256.1	PilN domain-containing protein	-
JFL57_RS03520 (JFL57_03520)	-	769863..770648 (-)	786	WP_012340257.1	hypothetical protein	-
JFL57_RS03525 (JFL57_03525)	-	770773..773313 (+)	2541	WP_198987018.1	penicillin-binding protein 1A	-

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 42275.55 Da
• Isoelectric Point: 6.4062

>NTDB_id=520974 JFL57_RS03505 WP_198987017.1 767670..768803(-) (comE) [Histophilus somni strain ASc-MMNZ-VFA-076]
MLIKNFLYFFLFLFTVSVELSARDPFDKRQRSIKKETNIQLDTKENLSKSTNEPNLTTTSIKLHYAKAADVMKSLTTXQG
SXLSSNGTFSFDXRSNLLLIQDNQETLNALKKLIKEMDQPIEQIAIEASIVTISDENLKELGVRWGIFEPTNNAHHLSGN
LAANGFQHLTEQLNVNFATTATPAGSIALQIAKINDRLLDLELTALERENNVEIIASPRLLTTNKQSASIKQGTEIPYVI
TGKKSDEQKVEFREAVLGLEVTPHISKDNTILLDLIVSQNSPGSRITYGQNEMVSIDKQEINTQVFAQDGETIVLGGVFH
DTITKGVDKVPLLGDIPILKRLFSRESERHQKRELVIFVTPRIIRSEQPNEIIKPLK

Nucleotide

• Length: 1134 bp

>NTDB_id=520974 JFL57_RS03505 WP_198987017.1 767670..768803(-) (comE) [Histophilus somni strain ASc-MMNZ-VFA-076]
ATGTTAATTAAAAATTTCTTATATTTCTTTTTGTTCTTATTCACAGTAAGTGTGGAATTATCTGCTAGAGATCCCTTTGA
TAAAAGACAAAGAAGCATAAAAAAAGAGACAAATATACAATTAGATACAAAGGAAAATTTGTCAAAATCGACTAATGAGC
CAAATTTAACGACGACTTCGATCAAATTACATTATGCTAAAGCGGCTGATGTAATGAAATCACTGACTACAKGTCAAGGT
TCATGKCTTTCATCAAATGGAACTTTTAGTTTTGATKAACGAAGTAACTTGCTCTTAATTCAGGATAATCAGGAAACTCT
CAATGCCTTAAAAAAATTAATCAAAGAAATGGATCAACCTATTGAACAAATTGCAATTGAAGCGAGTATTGTAACAATTA
GCGATGAAAATTTAAAAGAATTGGGGGTTCGTTGGGGAATTTTTGAGCCTACAAATAACGCTCATCATCTTTCAGGCAAT
CTAGCAGCAAACGGATTTCAGCATTTAACGGAACAACTTAACGTCAATTTTGCTACTACCGCAACACCTGCAGGTTCTAT
TGCTTTACAAATTGCCAAAATTAATGATCGACTTTTAGACTTAGAACTTACCGCACTTGAACGAGAAAATAATGTAGAAA
TTATTGCAAGCCCTCGTTTACTTACAACGAATAAGCAAAGTGCAAGTATTAAACAAGGAACTGAAATTCCTTATGTTATT
ACCGGCAAGAAATCTGATGAACAGAAAGTAGAGTTTAGAGAAGCAGTTTTAGGATTAGAAGTAACGCCACACATTTCTAA
AGACAATACTATTTTACTGGATCTCATTGTAAGCCAAAACTCCCCTGGAAGTCGTATTACTTATGGGCAAAATGAAATGG
TATCTATTGATAAACAAGAAATTAATACTCAAGTTTTTGCACAAGATGGGGAAACGATTGTGTTGGGTGGCGTATTTCAC
GATACAATCACAAAAGGAGTAGATAAAGTACCGCTGTTAGGAGACATACCTATATTAAAAAGACTGTTCAGCCGTGAAAG
TGAAAGACACCAAAAACGTGAATTAGTCATTTTTGTTACCCCAAGGATCATTCGTTCAGAACAACCTAATGAAATAATAA
AACCATTAAAATAG

Domains

Predicted by InterproScan.

• Bacterial type II and III secretion system protein (Secretin) (205-365)

• Bacterial type II/III secretion system short domain (Secretin_N) (60-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae 86-028NP	74.154	86.207	0.639
comE	Haemophilus influenzae Rd KW20	73.846	86.207	0.637
comE	Glaesserella parasuis strain SC1401	60.952	83.554	0.509
pilQ	Vibrio campbellii strain DS40M4	44.11	96.817	0.427
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	46.273	85.411	0.395
pilQ	Vibrio cholerae strain A1552	46.273	85.411	0.395