Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | JF649_RS01150 | Genome accession | NZ_CP066541 |
| Coordinates | 209929..211290 (+) | Length | 453 a.a. |
| NCBI ID | WP_030127062.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain MGAS270 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 173217..209848 | 209929..211290 | flank | 81 |
Gene organization within MGE regions
Location: 173217..211290
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JF649_RS00980 (JF649_00985) | - | 173217..174413 (+) | 1197 | WP_002986345.1 | glycine betaine/L-proline ABC transporter ATP-binding protein | - |
| JF649_RS00985 (JF649_00990) | - | 174429..176156 (+) | 1728 | WP_129321659.1 | ABC transporter permease/substrate binding protein | - |
| JF649_RS00990 (JF649_00995) | polA | 176287..178929 (+) | 2643 | WP_129321660.1 | DNA polymerase I | - |
| JF649_RS00995 (JF649_01000) | - | 179116..179571 (+) | 456 | WP_002986334.1 | CoA-binding protein | - |
| JF649_RS01000 (JF649_01005) | perR | 179623..180090 (+) | 468 | WP_002986328.1 | peroxide-responsive transcriptional repressor PerR | - |
| JF649_RS01005 (JF649_01010) | - | 180310..180546 (+) | 237 | WP_233436568.1 | hypothetical protein | - |
| JF649_RS01010 (JF649_01015) | - | 180768..182102 (+) | 1335 | WP_129321662.1 | phosphoadenosine phosphosulfate reductase | - |
| JF649_RS01015 (JF649_01020) | - | 182095..182625 (+) | 531 | WP_002987925.1 | ParB/RepB/Spo0J family partition protein | - |
| JF649_RS01020 (JF649_01025) | - | 182672..182827 (-) | 156 | Protein_154 | ISL3 family transposase | - |
| JF649_RS01025 (JF649_01030) | - | 182953..184103 (-) | 1151 | Protein_155 | IS3 family transposase | - |
| JF649_RS01030 (JF649_01035) | - | 184181..185491 (-) | 1311 | WP_002984130.1 | SLC13 family permease | - |
| JF649_RS01035 (JF649_01040) | nadC | 185715..186587 (+) | 873 | WP_010921848.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| JF649_RS01040 (JF649_01045) | - | 186850..188029 (-) | 1180 | Protein_158 | IS3 family transposase | - |
| JF649_RS01045 (JF649_01050) | - | 188115..188978 (-) | 864 | WP_014407270.1 | DUF975 family protein | - |
| JF649_RS08870 | - | 189015..189200 (+) | 186 | WP_002986321.1 | hypothetical protein | - |
| JF649_RS01050 (JF649_01055) | tgt | 189197..190339 (+) | 1143 | WP_012767590.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| JF649_RS01055 (JF649_01060) | - | 190544..190855 (+) | 312 | WP_012767589.1 | CHY zinc finger protein | - |
| JF649_RS01060 (JF649_01065) | - | 190859..191398 (+) | 540 | WP_003053494.1 | biotin transporter BioY | - |
| JF649_RS01065 (JF649_01070) | - | 191538..192317 (+) | 780 | WP_129321663.1 | MBL fold metallo-hydrolase | - |
| JF649_RS01070 (JF649_01075) | tadA | 192317..192832 (+) | 516 | WP_129321664.1 | tRNA adenosine(34) deaminase TadA | - |
| JF649_RS01075 (JF649_01080) | - | 193446..194678 (-) | 1233 | WP_009880892.1 | transglutaminase domain-containing protein | - |
| JF649_RS01085 (JF649_01090) | speG | 195078..195782 (+) | 705 | WP_010921857.1 | streptococcal pyrogenic exotoxin SpeG | - |
| JF649_RS01090 (JF649_01095) | - | 196238..197587 (+) | 1350 | WP_011888573.1 | glucose-6-phosphate isomerase | - |
| JF649_RS01095 (JF649_01100) | - | 197936..199444 (-) | 1509 | WP_129321665.1 | helix-turn-helix domain-containing protein | - |
| JF649_RS01100 (JF649_01105) | - | 199999..201132 (+) | 1134 | WP_000564846.1 | ISAs1-like element IS1548 family transposase | - |
| JF649_RS01105 (JF649_01110) | - | 201137..201310 (+) | 174 | WP_283102580.1 | hypothetical protein | - |
| JF649_RS01110 (JF649_01115) | - | 201458..202129 (+) | 672 | WP_129321666.1 | rhomboid family intramembrane serine protease | - |
| JF649_RS01115 (JF649_01120) | galU | 202228..203127 (-) | 900 | WP_129321667.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| JF649_RS01120 (JF649_01125) | - | 203160..204176 (-) | 1017 | WP_002986123.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| JF649_RS01125 (JF649_01130) | - | 204472..204921 (+) | 450 | WP_002986120.1 | MarR family transcriptional regulator | - |
| JF649_RS01130 (JF649_01135) | - | 204914..206620 (+) | 1707 | WP_010921864.1 | ABC transporter ATP-binding protein | - |
| JF649_RS01135 (JF649_01140) | - | 206623..208407 (+) | 1785 | WP_002986115.1 | ABC transporter ATP-binding protein | - |
| JF649_RS01140 (JF649_01145) | - | 208525..209292 (+) | 768 | WP_002986113.1 | epoxyqueuosine reductase QueH | - |
| JF649_RS01145 (JF649_01150) | - | 209402..209848 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| JF649_RS01150 (JF649_01155) | radA | 209929..211290 (+) | 1362 | WP_030127062.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49385.69 Da Isoelectric Point: 6.3735
>NTDB_id=520673 JF649_RS01150 WP_030127062.1 209929..211290(+) (radA) [Streptococcus pyogenes strain MGAS270]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTNMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTNMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=520673 JF649_RS01150 WP_030127062.1 209929..211290(+) (radA) [Streptococcus pyogenes strain MGAS270]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTAACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTGCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGACGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCTTT
GCAAGGCATTGACATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTAACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTGCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGACGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCTTT
GCAAGGCATTGACATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.872 |
100 |
0.859 |
| radA | Streptococcus pneumoniae D39 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae R6 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae Rx1 |
85.651 |
100 |
0.857 |
| radA | Streptococcus mitis SK321 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae TIGR4 |
85.651 |
100 |
0.857 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |