Detailed information NTG0520483

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JF380_RS10085
• Genome accession: NZ_CP066492
• Coordinates: 2010078..2011121 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain nan_175_F371_ch
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2005078..2016121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JF380_RS10055 (JF380_10055)	-	2005500..2006756 (-)	1257	WP_001789555.1	aminopeptidase	-
JF380_RS10060 (JF380_10060)	-	2006759..2006959 (-)	201	WP_000180460.1	DUF1128 family protein	-
JF380_RS10065 (JF380_10065)	-	2007106..2007570 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
JF380_RS10070 (JF380_10070)	-	2007577..2007852 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
JF380_RS10075 (JF380_10075)	-	2008130..2009347 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
JF380_RS10080 (JF380_10080)	vraR	2009459..2010088 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
JF380_RS10085 (JF380_10085)	vraS	2010078..2011121 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JF380_RS10090 (JF380_10090)	liaF	2011118..2011819 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
JF380_RS10095 (JF380_10095)	-	2011834..2012220 (-)	387	WP_001110179.1	hypothetical protein	-
JF380_RS10100 (JF380_10100)	map	2012437..2013195 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
JF380_RS10105 (JF380_10105)	-	2013785..2014771 (+)	987	WP_198914109.1	FUSC family protein	-
JF380_RS10110 (JF380_10110)	-	2015261..2015674 (-)	414	WP_001566709.1	hypothetical protein	-
JF380_RS10115 (JF380_10115)	-	2015703..2015814 (-)	112	Protein_1972	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=520483 JF380_RS10085 WP_001017131.1 2010078..2011121(-) (vraS) [Staphylococcus aureus strain nan_175_F371_ch]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=520483 JF380_RS10085 WP_001017131.1 2010078..2011121(-) (vraS) [Staphylococcus aureus strain nan_175_F371_ch]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1