Detailed information NTG0520445

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JF379_RS13535
• Genome accession: NZ_CP066488
• Coordinates: 2715315..2716202 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain ncr_155_F133
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2710315..2721202

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JF379_RS13505 (JF379_13505)	-	2710334..2710426 (+)	93	WP_010956583.1	hypothetical protein	-
JF379_RS13510 (JF379_13510)	-	2710534..2711031 (-)	498	WP_001065268.1	glutathione peroxidase	-
JF379_RS13515 (JF379_13515)	-	2711041..2711301 (-)	261	WP_001791974.1	hypothetical protein	-
JF379_RS13520 (JF379_13520)	-	2711683..2711796 (-)	114	Protein_2642	hypothetical protein	-
JF379_RS13525 (JF379_13525)	-	2712455..2714455 (-)	2001	WP_000776740.1	ABC transporter permease	-
JF379_RS13530 (JF379_13530)	-	2714452..2715207 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
JF379_RS13535 (JF379_13535)	braS	2715315..2716202 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JF379_RS13540 (JF379_13540)	braR	2716213..2716878 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JF379_RS13545 (JF379_13545)	-	2716904..2717104 (-)	201	WP_000604727.1	hypothetical protein	-
JF379_RS13550 (JF379_13550)	-	2717302..2718726 (+)	1425	WP_000953748.1	alkaline phosphatase	-
JF379_RS14390	-	2718786..2718887 (-)	102	WP_000731972.1	SE2200 family small protein	-
JF379_RS13560 (JF379_13560)	-	2719009..2719464 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JF379_RS13565 (JF379_13565)	-	2719709..2720470 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=520445 JF379_RS13535 WP_000143417.1 2715315..2716202(-) (braS) [Staphylococcus aureus strain ncr_155_F133]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=520445 JF379_RS13535 WP_000143417.1 2715315..2716202(-) (braS) [Staphylococcus aureus strain ncr_155_F133]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99