Detailed information NTG0520440

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JF379_RS10095
• Genome accession: NZ_CP066488
• Coordinates: 2030987..2032030 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ncr_155_F133
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2025987..2037030

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JF379_RS10065 (JF379_10065)	-	2026415..2027671 (-)	1257	WP_001793428.1	aminopeptidase	-
JF379_RS10070 (JF379_10070)	-	2027674..2027874 (-)	201	WP_000180460.1	DUF1128 family protein	-
JF379_RS10075 (JF379_10075)	-	2028021..2028485 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
JF379_RS10080 (JF379_10080)	-	2028492..2028767 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
JF379_RS10085 (JF379_10085)	-	2029045..2030256 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
JF379_RS10090 (JF379_10090)	vraR	2030368..2030997 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
JF379_RS10095 (JF379_10095)	vraS	2030987..2032030 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JF379_RS10100 (JF379_10100)	liaF	2032027..2032728 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
JF379_RS10105 (JF379_10105)	-	2032743..2033129 (-)	387	WP_001110179.1	hypothetical protein	-
JF379_RS10110 (JF379_10110)	map	2033346..2034104 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
JF379_RS10115 (JF379_10115)	-	2034635..2035621 (+)	987	WP_000999713.1	FUSC family protein	-
JF379_RS10120 (JF379_10120)	-	2036111..2036524 (-)	414	WP_001837236.1	hypothetical protein	-
JF379_RS10125 (JF379_10125)	-	2036553..2036663 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=520440 JF379_RS10095 WP_001017131.1 2030987..2032030(-) (vraS) [Staphylococcus aureus strain ncr_155_F133]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=520440 JF379_RS10095 WP_001017131.1 2030987..2032030(-) (vraS) [Staphylococcus aureus strain ncr_155_F133]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTAAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1