Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   SMUGS5_RS06275 Genome accession   NC_018089
Coordinates   1315481..1316374 (+) Length   297 a.a.
NCBI ID   WP_002262721.1    Uniprot ID   A0A090B2L0
Organism   Streptococcus mutans GS-5     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1310481..1321374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS10750 (SMUGS5_06220) - 1312445..1312573 (-) 129 WP_002262718.1 hypothetical protein -
  SMUGS5_RS10665 - 1312608..1312838 (-) 231 WP_002282891.1 hypothetical protein -
  SMUGS5_RS06265 gbpC 1312968..1314719 (-) 1752 Protein_1222 glucan-binding protein GbpC -
  SMUGS5_RS06270 (SMUGS5_06235) - 1314882..1315166 (-) 285 WP_002262720.1 helix-turn-helix transcriptional regulator -
  SMUGS5_RS06275 (SMUGS5_06240) irvR 1315481..1316374 (+) 894 WP_002262721.1 LexA family transcriptional regulator IrvR Regulator
  SMUGS5_RS06280 (SMUGS5_06245) - 1318099..1318476 (-) 378 WP_002279856.1 type II toxin-antitoxin system HicB family antitoxin -
  SMUGS5_RS06285 (SMUGS5_06250) - 1318494..1318685 (-) 192 WP_002265423.1 type II toxin-antitoxin system HicA family toxin -
  SMUGS5_RS06290 (SMUGS5_06255) csn2 1318782..1319444 (-) 663 WP_002279857.1 type II-A CRISPR-associated protein Csn2 -
  SMUGS5_RS06295 (SMUGS5_06260) cas2 1319434..1319778 (-) 345 WP_002263547.1 CRISPR-associated endonuclease Cas2 -
  SMUGS5_RS06300 (SMUGS5_06265) cas1 1319775..1320641 (-) 867 WP_002279858.1 type II CRISPR-associated endonuclease Cas1 -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33651.40 Da        Isoelectric Point: 6.7038

>NTDB_id=52037 SMUGS5_RS06275 WP_002262721.1 1315481..1316374(+) (irvR) [Streptococcus mutans GS-5]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTEDKVADKSNHTQYQKVVDSFIAKELNDQTI
IHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALIVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=52037 SMUGS5_RS06275 WP_002262721.1 1315481..1316374(+) (irvR) [Streptococcus mutans GS-5]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCAATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCCACTATCCTTAACATTCCTACAAGTAGTCTTAATGAATATGTTAAAGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTCTCCAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAAGAACAAGATGAAACAGCAAGCTTGTCTGCCAGTGATGAAACGACTGAGGATAAAG
TTGCTGACAAATCAAATCATACGCAGTATCAAAAGGTTGTTGATTCTTTTATTGCCAAAGAATTAAACGATCAGACAATT
ATTCATTGGGATAATGTGATAAAAGCTAAGGATTTGTATCAAACCTTTGGACGTCAATACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTATTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Peptidase S24-like (Peptidase_S24)

(184-296)

Helix-turn-helix (HTH_3)

(22-70)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A090B2L0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

100

100

1

Multiple sequence alignment