Detailed information NTG0519773

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: JEQ24_RS18640
• Genome accession: NZ_CP066379
• Coordinates: 3709046..3710209 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain ID-A04
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3704046..3715209

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JEQ24_RS18610 (JEQ24_18445)	-	3704311..3704730 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
JEQ24_RS18615 (JEQ24_18450)	comFC	3704804..3705493 (-)	690	WP_197538213.1	ComF family protein	Machinery gene
JEQ24_RS18620 (JEQ24_18455)	-	3705499..3705783 (-)	285	WP_022553866.1	competence protein ComFB	-
JEQ24_RS18625 (JEQ24_18460)	comFA	3705841..3707226 (-)	1386	WP_022553867.1	DEAD/DEAH box helicase	Machinery gene
JEQ24_RS18630 (JEQ24_18465)	-	3707334..3708182 (-)	849	WP_003151387.1	DegV family protein	-
JEQ24_RS18635 (JEQ24_18470)	degU	3708280..3708969 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
JEQ24_RS18640 (JEQ24_18475)	degS	3709046..3710209 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
JEQ24_RS18645 (JEQ24_18480)	-	3710432..3711079 (+)	648	WP_007407485.1	YigZ family protein	-
JEQ24_RS18650 (JEQ24_18485)	-	3711084..3712298 (+)	1215	WP_022553868.1	LCP family protein	-
JEQ24_RS18655 (JEQ24_18490)	-	3712398..3713474 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
JEQ24_RS18660 (JEQ24_18495)	-	3713606..3714802 (-)	1197	WP_022553869.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=519773 JEQ24_RS18640 WP_007407484.1 3709046..3710209(-) (degS) [Bacillus velezensis strain ID-A04]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=519773 JEQ24_RS18640 WP_007407484.1 3709046..3710209(-) (degS) [Bacillus velezensis strain ID-A04]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951