Detailed information NTG0519697

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: JEQ23_RS18945
• Genome accession: NZ_CP066378
• Coordinates: 3750641..3751804 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain ID-A03
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3745641..3756804

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JEQ23_RS18915 (JEQ23_18740)	-	3745906..3746325 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
JEQ23_RS18920 (JEQ23_18745)	comFC	3746399..3747088 (-)	690	WP_197538213.1	ComF family protein	Machinery gene
JEQ23_RS18925 (JEQ23_18750)	-	3747094..3747378 (-)	285	WP_022553866.1	competence protein ComFB	-
JEQ23_RS18930 (JEQ23_18755)	comFA	3747436..3748821 (-)	1386	WP_022553867.1	DEAD/DEAH box helicase	Machinery gene
JEQ23_RS18935 (JEQ23_18760)	-	3748929..3749777 (-)	849	WP_003151387.1	DegV family protein	-
JEQ23_RS18940 (JEQ23_18765)	degU	3749875..3750564 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
JEQ23_RS18945 (JEQ23_18770)	degS	3750641..3751804 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
JEQ23_RS18950 (JEQ23_18775)	-	3752027..3752674 (+)	648	WP_007407485.1	YigZ family protein	-
JEQ23_RS18955 (JEQ23_18780)	-	3752679..3753893 (+)	1215	WP_022553868.1	LCP family protein	-
JEQ23_RS18960 (JEQ23_18785)	-	3753993..3755069 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
JEQ23_RS18965 (JEQ23_18790)	-	3755201..3756397 (-)	1197	WP_022553869.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=519697 JEQ23_RS18945 WP_007407484.1 3750641..3751804(-) (degS) [Bacillus velezensis strain ID-A03]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=519697 JEQ23_RS18945 WP_007407484.1 3750641..3751804(-) (degS) [Bacillus velezensis strain ID-A03]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951