Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   JFU10_RS16475 Genome accession   NZ_CP066337
Coordinates   3301085..3301741 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain Mr12     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3296085..3306741
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JFU10_RS16445 oppF 3296610..3297527 (+) 918 WP_070081625.1 oligopeptide ABC transporter ATP-binding protein OppF -
  JFU10_RS16450 - 3297634..3298821 (+) 1188 WP_071391995.1 putative glycoside hydrolase -
  JFU10_RS16455 - 3298939..3299517 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  JFU10_RS16460 spx 3299696..3300091 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  JFU10_RS16465 - 3300149..3300805 (-) 657 WP_003155033.1 TerC family protein -
  JFU10_RS16470 - 3300988..3301104 (+) 117 WP_416135599.1 hypothetical protein -
  JFU10_RS16475 mecA 3301085..3301741 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  JFU10_RS16480 - 3301893..3303053 (+) 1161 WP_198863640.1 competence protein CoiA family protein -
  JFU10_RS16485 pepF 3303281..3305110 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  JFU10_RS16490 - 3305148..3305315 (-) 168 WP_003155026.1 hypothetical protein -
  JFU10_RS16495 spxH 3305601..3306503 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=519352 JFU10_RS16475 WP_003155032.1 3301085..3301741(+) (mecA) [Bacillus velezensis strain Mr12]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=519352 JFU10_RS16475 WP_003155032.1 3301085..3301741(+) (mecA) [Bacillus velezensis strain Mr12]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895