Detailed information NTG0518273

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: JC773_RS21300
• Genome accession: NZ_CP066185
• Coordinates: 4182940..4183734 (-)
• Length: 264 a.a.
• NCBI ID: WP_012095325.1
• Uniprot ID: -
• Organism: Bacillus cytotoxicus strain PDT2.12
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	4174044..4184949	4182940..4183734	within	0
IScluster/Tn	4175804..4185389	4182940..4183734	within	0

Gene organization within MGE regions

Location: 4174044..4185389

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JC773_RS21250 (JC773_21250)	-	4174044..4174277 (+)	234	WP_012095322.1	DUF2627 domain-containing protein	-
JC773_RS21255 (JC773_21255)	-	4174374..4175102 (-)	729	WP_012095323.1	glycerophosphodiester phosphodiesterase	-
JC773_RS21260 (JC773_21260)	-	4175152..4175298 (+)	147	WP_012095324.1	YycC family protein	-
JC773_RS21265 (JC773_21265)	tnpA	4175727..4176169 (-)	443	Protein_4177	IS200/IS605 family transposase	-
JC773_RS21270 (JC773_21270)	-	4176469..4178958 (-)	2490	WP_087099099.1	FtsX-like permease family protein	-
JC773_RS21275 (JC773_21275)	-	4178955..4179716 (-)	762	WP_087099101.1	ABC transporter ATP-binding protein	-
JC773_RS21280 (JC773_21280)	-	4179738..4180433 (-)	696	WP_242136512.1	ABC transporter ATP-binding protein	-
JC773_RS21290 (JC773_21290)	-	4181777..4182325 (-)	549	WP_242136721.1	hypothetical protein	-
JC773_RS22490	-	4182622..4182807 (-)	186	WP_242136722.1	hypothetical protein	-
JC773_RS21300 (JC773_21300)	spo0A	4182940..4183734 (-)	795	WP_012095325.1	sporulation transcription factor Spo0A	Regulator

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29453.21 Da
• Isoelectric Point: 7.4717

>NTDB_id=518273 JC773_RS21300 WP_012095325.1 4182940..4183734(-) (spo0A) [Bacillus cytotoxicus strain PDT2.12]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKEKQPDVLVLDIIMPHLDGLAVLEKMRHIERLKQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKTNAAIKRPLPSFRSVTTADGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=518273 JC773_RS21300 WP_012095325.1 4182940..4183734(-) (spo0A) [Bacillus cytotoxicus strain PDT2.12]
GTGGAGAAAATCAAAGTATGTCTTGTGGATGATAATAAAGAATTGGTATCAATGCTAGAAAGTTATGTTGCTGCCCAAGA
TGATATGGAAGTAATCGGAACGGCTTATAATGGTCAAGAATGTTTAAATTTATTAAAAGAAAAACAACCTGATGTACTCG
TTTTAGACATTATTATGCCACATTTAGATGGCCTAGCAGTACTGGAGAAAATGCGACATATTGAACGACTAAAACAACCG
AATGTTATTATGTTAACAGCATTTGGGCAAGAAGATGTGACAAAGAAAGCAGTTGATCTAGGAGCTTCTTATTTCATATT
AAAACCATTTGATATGGAGAATTTAACGAGTCATATTCGTCAAGTAAGTGGTAAAACAAATGCTGCGATAAAACGCCCAC
TACCATCTTTCCGATCGGTAACAACAGCAGATGGAAAACCGAAAAATTTAGATGCGAGTATTACGAGCATTATTCACGAA
ATTGGTGTCCCAGCTCATATTAAAGGATATATGTATTTACGCGAAGCAATTTCTATGGTGTACAACGACATTGAGTTGTT
AGGATCTATTACGAAAGTATTATATCCAGATATCGCTAAGAAATATAATACAACTGCAAGTCGTGTGGAACGTGCAATTC
GACATGCGATTGAAGTAGCATGGAGCCGTGGGAATATTGATTCTATCTCATCTTTATTCGGTTATACCGTATCCATGTCA
AAAGCAAAACCGACGAATTCCGAATTTATTGCAATGGTTGCGGATAAATTGAGACTTGAACATAAGGCGAGTTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	81.648	100	0.826