Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   JC777_RS21645 Genome accession   NZ_CP066184
Coordinates   4058863..4059537 (-) Length   224 a.a.
NCBI ID   WP_011983993.1    Uniprot ID   A7GM82
Organism   Bacillus cytotoxicus strain SM1.1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 4053863..4064537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JC777_RS21630 (JC777_21635) pepF 4054006..4055832 (-) 1827 WP_011983996.1 oligoendopeptidase F Regulator
  JC777_RS21635 (JC777_21640) - 4055925..4057127 (-) 1203 WP_109090165.1 competence protein CoiA family protein -
  JC777_RS21640 (JC777_21645) cls 4057219..4058763 (-) 1545 WP_011983994.1 cardiolipin synthase -
  JC777_RS21645 (JC777_21650) mecA 4058863..4059537 (-) 675 WP_011983993.1 adaptor protein MecA Regulator
  JC777_RS21650 (JC777_21655) - 4059945..4060619 (+) 675 WP_011983992.1 TerC family protein -
  JC777_RS21655 (JC777_21660) spx 4060702..4061097 (-) 396 WP_000258267.1 transcriptional regulator Spx -
  JC777_RS21660 (JC777_21665) - 4061683..4061886 (+) 204 WP_011983991.1 hypothetical protein -
  JC777_RS21665 (JC777_21670) - 4061939..4063576 (-) 1638 WP_011983990.1 peptide ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26744.89 Da        Isoelectric Point: 4.0439

>NTDB_id=518218 JC777_RS21645 WP_011983993.1 4058863..4059537(-) (mecA) [Bacillus cytotoxicus strain SM1.1]
MDIERINDHTMKFFITYVDIEDRGFNREEIWYNRERSEQLFWEMMDEARDYDDFFIDGPLWIQVQALDKGIEVLVTKAQL
SKDGQKLELPIGLDKIIDIPLDESIESLFQQELEEEGTVTNFNEDGTLGFLIKFEDFEDVISLSHRLIFEDIKDQLYSFE
NRYYVYVEFDEVLHDEEEIDRILSIILEYGEESTLTIHRVSEYGKEIMSEHALETIRKHFPSKT

Nucleotide


Download         Length: 675 bp        

>NTDB_id=518218 JC777_RS21645 WP_011983993.1 4058863..4059537(-) (mecA) [Bacillus cytotoxicus strain SM1.1]
TTGGATATTGAAAGAATTAATGATCATACGATGAAATTTTTCATTACGTACGTTGATATAGAGGATAGAGGATTTAATCG
CGAAGAAATTTGGTATAATCGCGAGCGAAGTGAACAATTATTTTGGGAAATGATGGATGAAGCACGTGATTACGATGACT
TCTTTATTGATGGACCATTGTGGATTCAAGTACAAGCGTTAGACAAAGGGATTGAAGTGCTTGTAACGAAAGCACAGCTT
TCAAAAGATGGACAAAAATTAGAATTACCGATAGGTCTCGATAAAATTATTGATATTCCTCTAGATGAAAGCATTGAATC
GTTATTTCAACAAGAATTAGAGGAAGAAGGAACGGTTACGAATTTTAATGAAGATGGAACACTTGGATTTTTAATTAAGT
TTGAAGATTTTGAAGATGTTATTTCATTAAGTCATCGCCTAATTTTTGAAGATATAAAAGACCAACTATATTCATTTGAA
AATCGTTATTATGTATATGTTGAATTCGATGAAGTGCTACACGATGAGGAAGAAATTGACCGTATTTTAAGTATTATTTT
AGAATATGGAGAGGAATCTACTTTAACGATTCACCGTGTGAGTGAGTATGGGAAAGAGATTATGAGCGAACATGCACTTG
AGACAATTCGTAAGCATTTTCCTTCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A7GM82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

59.91

99.107

0.594