Detailed information NTG0518153

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: JC774_RS09780
• Genome accession: NZ_CP066179
• Coordinates: 1857233..1858027 (+)
• Length: 264 a.a.
• NCBI ID: WP_012095325.1
• Uniprot ID: -
• Organism: Bacillus cytotoxicus strain SM2.8
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1856018..1866593	1857233..1858027	within	0
IScluster/Tn	1855578..1868182	1857233..1858027	within	0

Gene organization within MGE regions

Location: 1855578..1868182

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JC774_RS09775 (JC774_09775)	-	1855578..1856911 (+)	1334	WP_210351372.1	IS3 family transposase	-
JC774_RS09780 (JC774_09780)	spo0A	1857233..1858027 (+)	795	WP_012095325.1	sporulation transcription factor Spo0A	Regulator
JC774_RS22135	-	1858160..1858345 (+)	186	WP_242136722.1	hypothetical protein	-
JC774_RS09790 (JC774_09790)	-	1858642..1859190 (+)	549	WP_242136721.1	hypothetical protein	-
JC774_RS09795 (JC774_09795)	-	1859254..1860395 (+)	1142	WP_094374389.1	IS3-like element ISBce13 family transposase	-
JC774_RS09800 (JC774_09800)	-	1860534..1861229 (+)	696	WP_242136512.1	ABC transporter ATP-binding protein	-
JC774_RS09805 (JC774_09805)	-	1861251..1862012 (+)	762	WP_087099101.1	ABC transporter ATP-binding protein	-
JC774_RS09810 (JC774_09810)	-	1862009..1864498 (+)	2490	WP_087099099.1	FtsX-like permease family protein	-
JC774_RS09815 (JC774_09815)	tnpA	1864798..1865240 (+)	443	Protein_1808	IS200/IS605 family transposase	-
JC774_RS09820 (JC774_09820)	-	1865669..1865815 (-)	147	WP_012095324.1	YycC family protein	-
JC774_RS09825 (JC774_09825)	-	1865865..1866593 (+)	729	WP_012095323.1	glycerophosphodiester phosphodiesterase	-
JC774_RS09830 (JC774_09830)	-	1866722..1868182 (+)	1461	WP_048723387.1	IS1182-like element ISBcy1 family transposase	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29453.21 Da
• Isoelectric Point: 7.4717

>NTDB_id=518153 JC774_RS09780 WP_012095325.1 1857233..1858027(+) (spo0A) [Bacillus cytotoxicus strain SM2.8]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKEKQPDVLVLDIIMPHLDGLAVLEKMRHIERLKQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKTNAAIKRPLPSFRSVTTADGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=518153 JC774_RS09780 WP_012095325.1 1857233..1858027(+) (spo0A) [Bacillus cytotoxicus strain SM2.8]
GTGGAGAAAATCAAAGTATGTCTTGTGGATGATAATAAAGAATTGGTATCAATGCTAGAAAGTTATGTTGCTGCCCAAGA
TGATATGGAAGTAATCGGAACGGCTTATAATGGTCAAGAATGTTTAAATTTATTAAAAGAAAAACAACCTGATGTACTCG
TTTTAGACATTATTATGCCACATTTAGATGGCCTAGCAGTACTGGAGAAAATGCGACATATTGAACGACTAAAACAACCG
AATGTTATTATGTTAACAGCATTTGGGCAAGAAGATGTGACAAAGAAAGCAGTTGATCTAGGAGCTTCTTATTTCATATT
AAAACCATTTGATATGGAGAATTTAACGAGTCATATTCGTCAAGTAAGTGGTAAAACAAATGCTGCGATAAAACGCCCAC
TACCATCTTTCCGATCGGTAACAACAGCAGATGGAAAACCGAAAAATTTAGATGCGAGTATTACGAGCATTATTCACGAA
ATTGGTGTCCCAGCTCATATTAAAGGATATATGTATTTACGCGAAGCAATTTCTATGGTGTACAACGACATTGAGTTGTT
AGGATCTATTACGAAAGTATTATATCCAGATATCGCTAAGAAATATAATACAACTGCAAGTCGTGTGGAACGTGCAATTC
GACATGCGATTGAAGTAGCATGGAGCCGTGGGAATATTGATTCTATCTCATCTTTATTCGGTTATACCGTATCCATGTCA
AAAGCAAAACCGACGAATTCCGAATTTATTGCAATGGTTGCGGATAAATTGAGACTTGAACATAAGGCGAGTTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	81.648	100	0.826