Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   JDY60_RS06840 Genome accession   NZ_CP066172
Coordinates   1449739..1450776 (-) Length   345 a.a.
NCBI ID   WP_000730772.1    Uniprot ID   A0A1X1GB13
Organism   Streptococcus oralis strain SF100     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1444739..1455776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS06815 (JDY60_06815) - 1445634..1446965 (-) 1332 WP_200370492.1 hemolysin family protein -
  JDY60_RS06820 (JDY60_06820) - 1447101..1447924 (-) 824 Protein_1336 DNA/RNA non-specific endonuclease -
  JDY60_RS06825 (JDY60_06825) - 1447965..1448159 (-) 195 WP_000739700.1 DNA-directed RNA polymerase subunit beta -
  JDY60_RS06830 (JDY60_06830) murA 1448146..1449429 (-) 1284 WP_180833558.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  JDY60_RS06835 (JDY60_06835) - 1449453..1449683 (-) 231 WP_002892633.1 DUF1146 family protein -
  JDY60_RS06840 (JDY60_06840) sepM 1449739..1450776 (-) 1038 WP_000730772.1 SepM family pheromone-processing serine protease Regulator
  JDY60_RS06845 (JDY60_06845) coaD 1450760..1451248 (-) 489 WP_200370493.1 pantetheine-phosphate adenylyltransferase -
  JDY60_RS06850 (JDY60_06850) rsmD 1451238..1451777 (-) 540 WP_002874201.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  JDY60_RS06855 (JDY60_06855) asnA 1451842..1452834 (-) 993 WP_000747998.1 aspartate--ammonia ligase -
  JDY60_RS06860 (JDY60_06860) - 1452944..1453627 (-) 684 WP_200370494.1 Bax inhibitor-1/YccA family protein -
  JDY60_RS06865 (JDY60_06865) - 1453682..1454422 (-) 741 WP_200370495.1 RNA methyltransferase -
  JDY60_RS06870 (JDY60_06870) - 1454456..1454734 (+) 279 WP_001174609.1 acylphosphatase -
  JDY60_RS06875 (JDY60_06875) yidC 1454812..1455741 (+) 930 WP_049479479.1 membrane protein insertase YidC -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37539.74 Da        Isoelectric Point: 5.5304

>NTDB_id=518067 JDY60_RS06840 WP_000730772.1 1449739..1450776(-) (sepM) [Streptococcus oralis strain SF100]
MKKKTRWPLYVILALVLTFLAFVVPLPYYIEVPGGAEDIRRVLKVNETEDTEAGAYQFVTVGIRHATLSHLVYAWLTPFT
DIRSAKETTGGSTDAEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYLGVYVLTVTDNSTFKGILNIADTVTAVNDKTF
DSSKDLVDYVNSQQLGDTVKVTYEEDGKVKSAEGKIITLENGKNGIGIGLIDRTEVTSDVPIRFSTAGIGGPSAGLMFSL
AIYTQIADPGLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVAASRQGANIFFAPDNPVTEEAKKADPNAKSNYETALEAAK
TIKTEMKIVPVKTLQDAIDYLKNNP

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=518067 JDY60_RS06840 WP_000730772.1 1449739..1450776(-) (sepM) [Streptococcus oralis strain SF100]
ATGAAGAAAAAAACTAGATGGCCCTTATATGTCATCCTAGCACTAGTATTGACTTTTTTAGCATTTGTAGTACCTTTACC
TTACTACATAGAAGTTCCGGGTGGAGCGGAGGATATCCGTCGCGTTTTGAAAGTCAATGAAACAGAGGATACGGAAGCAG
GAGCTTACCAGTTTGTAACAGTTGGTATTCGACACGCAACCCTATCGCATCTTGTCTATGCTTGGTTAACACCTTTCACG
GATATTAGAAGTGCCAAGGAGACTACGGGTGGCTCTACTGATGCAGAGTTTATGCGGATCAATCAGTTTTACATGCAAAC
TTCTCAAAATATGGCCAAGTATCAAGGATTGAAGACGGCTGGTAAAGATATCGAACTCAAGTATCTTGGAGTCTATGTCT
TGACCGTGACGGACAATTCAACTTTTAAGGGTATTCTGAACATTGCAGATACTGTGACGGCTGTTAATGACAAAACATTT
GACAGTTCAAAAGACTTGGTCGACTATGTCAACTCTCAACAATTAGGGGACACGGTCAAGGTAACCTATGAAGAAGACGG
AAAAGTCAAGTCTGCAGAAGGTAAAATTATCACTCTCGAAAACGGGAAAAACGGGATTGGGATTGGCTTGATTGACCGTA
CGGAAGTGACCAGTGACGTTCCCATTCGCTTCTCTACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCCATCTATACCCAGATAGCAGATCCAGGACTTCGTAATGGCCGCATCGTTGCGGGAACGGGAACTATTGATCGCGATGG
AAATGTTGGCGACATCGGTGGAATTGACAAAAAAGTGGTTGCAGCCTCTCGTCAGGGAGCCAACATCTTTTTTGCTCCTG
ACAATCCAGTCACCGAGGAAGCAAAAAAAGCAGATCCAAATGCGAAAAGCAACTATGAAACAGCCCTAGAAGCTGCCAAA
ACGATCAAGACAGAGATGAAAATCGTTCCTGTTAAAACTTTGCAGGATGCGATTGATTACCTTAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(129-193)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(230-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1GB13

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

59.942

99.13

0.594