Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   I6I02_RS09885 Genome accession   NZ_CP066093
Coordinates   2144174..2146624 (-) Length   816 a.a.
NCBI ID   WP_048790655.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2139174..2151624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS09875 (I6I02_09875) pbp3 2141396..2142643 (+) 1248 WP_198463546.1 D-alanyl-D-alanine carboxypeptidase PBP3 -
  I6I02_RS09880 (I6I02_09880) pbp3 2142788..2144044 (+) 1257 WP_198463547.1 D-alanyl-D-alanine carboxypeptidase PBP3 -
  I6I02_RS09885 (I6I02_09885) clpC 2144174..2146624 (-) 2451 WP_048790655.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  I6I02_RS09890 (I6I02_09890) - 2146625..2147080 (-) 456 WP_002889615.1 CtsR family transcriptional regulator -
  I6I02_RS09895 (I6I02_09895) - 2147379..2147849 (+) 471 WP_004182164.1 COG2426 family protein -
  I6I02_RS09900 (I6I02_09900) tsf 2147955..2148995 (-) 1041 WP_002886343.1 translation elongation factor Ts -
  I6I02_RS09905 (I6I02_09905) rpsB 2149106..2149873 (-) 768 WP_002886342.1 30S ribosomal protein S2 -
  I6I02_RS09910 (I6I02_09910) ahpC 2150146..2150706 (+) 561 WP_002886340.1 alkyl hydroperoxide reductase subunit C -

Sequence

Protein


Download         Length: 816 a.a.        Molecular weight: 90223.55 Da        Isoelectric Point: 5.9160

>NTDB_id=517389 I6I02_RS09885 WP_048790655.1 2144174..2146624(-) (clpC) [Streptococcus salivarius strain FDAARGOS_1045]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALEAMLQEAEGIAGVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKTSGNFANMMQPPQSSTGELADYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGDVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVAEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKASQKAKLPKPAL
VDADQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMVKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide


Download         Length: 2451 bp        

>NTDB_id=517389 I6I02_RS09885 WP_048790655.1 2144174..2146624(-) (clpC) [Streptococcus salivarius strain FDAARGOS_1045]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCGCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACAGCAGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCAGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGAGGCTATGTTGCAAGAGGCAGAGGGAATTGCTGGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTTCTCCTTCATAAAGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGTATTATCGATTTACGACGTTCTTTGGAGCGTTATGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCATGACCTTCGTAAGCCTAAAAAATCAAAGACATCAGGAAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAGTTGGCAGATTATACCAAGGACTTAACGGCAGTAGCCGAGTCAGGTGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAGATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTA
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTGGCACAGCGTATTGCTTCAGGCGATGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAAATCATCGATGAGATTGAAGCTGATGGAAAAATCATTCTCTTTATTGACGAACTGCATACGATTATTGGTTCT
GGTTCAGGTATTGATAGTACCTTAGATGCGGCAAATATTTTGAAACCTGCTCTAGCACGTGGAACTCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAAAAAGATGCAGCTCTTTCTCGTCGTTTTGCTAAGATTACAATTG
AGGAGCCAAGTGTAGCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCAGTTGAGACAGCGGTCAAGGCGGCCCACCGTTATTTGACGAGTAAAAACTTGCCTGACTCTGCCATTGA
CCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTCGTATTAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CGCTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAGGCTAGCCAAAAAGCAAAATTACCAAAACCTGCCTTG
GTAGATGCGGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATCCCTGTTGAGAAGATGACTCAGGCAGATAGCAA
GCGTTATTTGAATCTGGAAGCAGAGCTTCACAAACGTGTTATTGGCCAAGACGAAGCAGTTTCAGCGATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGAAAACGTCCGATTGGTTCCTTCATGTTCCTTGGGCCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCATTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGACTTAACGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGCGGTGAGTTAACAG
AAAAAGTTCGTAATAAGCCTTACTCAGTTCTTCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTTAATATTCTC
TTACAAGTTTTGGATGACGGTGTCTTGACGGATAGTCGAGGTCGTAAAGTTGACTTCTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACCGTTGGTTTTGGAGTCCAAGACATTTCTCATAATCACCAAG
CTATGCAGTCACGTATCATGGAAGAGCTTAAGAAGGCCTACCGACCAGAGTTTATCAACCGTATTGATGAAAAGGTTGTC
TTCCATAGTTTAGAGGAAGAGCAGCTTCGTGAGATTGTCAAGATTATGGTAAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAGTTCCAACCAGCTGCCCTCAAACATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAAGTTATCTGAGCTCTTACTAGGTGGCCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(377-457)

AAA domain (Cdc48 subfamily) (AAA_2)

(546-717)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(724-804)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-46)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(109-135)

ATPase family associated with various cellular activities (AAA) (AAA)

(238-370)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus thermophilus LMG 18311

95.098

100

0.951
  clpC Streptococcus thermophilus LMD-9

94.975

100

0.95
  clpC Streptococcus mutans UA159

73.039

100

0.73
  clpC Streptococcus pneumoniae TIGR4

67.402

100

0.674
  clpC Streptococcus pneumoniae Rx1

67.402

100

0.674
  clpC Streptococcus pneumoniae D39

67.402

100

0.674
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

50.421

100

0.513
  clpC Bacillus subtilis subsp. subtilis str. 168

47.266

100

0.477
  clpE Streptococcus mutans UA159

48.243

76.716

0.37
  clpC Lactococcus lactis subsp. cremoris KW2

45.038

80.27

0.362