Detailed information NTG0517364

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: I6I02_RS06475
• Genome accession: NZ_CP066093
• Coordinates: 1432798..1435068 (+)
• Length: 756 a.a.
• NCBI ID: WP_073687523.1
• Uniprot ID: A0AB37D945
• Organism: Streptococcus salivarius strain FDAARGOS_1045
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1427798..1440068

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I02_RS06450 (I6I02_06450)	-	1428899..1429375 (-)	477	WP_198463282.1	ferrous iron transport protein A	-
I6I02_RS06455 (I6I02_06455)	-	1429547..1430281 (-)	735	WP_037602114.1	amino acid ABC transporter ATP-binding protein	-
I6I02_RS06460 (I6I02_06460)	-	1430281..1430961 (-)	681	WP_002890385.1	amino acid ABC transporter permease	-
I6I02_RS06465 (I6I02_06465)	-	1431276..1431506 (-)	231	WP_002885970.1	DUF1797 family protein	-
I6I02_RS06470 (I6I02_06470)	argF	1431575..1432555 (-)	981	WP_198463283.1	ornithine carbamoyltransferase	-
I6I02_RS06475 (I6I02_06475)	clpE	1432798..1435068 (+)	2271	WP_073687523.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I6I02_RS06480 (I6I02_06480)	-	1435211..1435669 (+)	459	WP_084914834.1	NUDIX hydrolase	-
I6I02_RS06485 (I6I02_06485)	-	1435679..1435981 (+)	303	WP_002885967.1	DUF1827 family protein	-
I6I02_RS06490 (I6I02_06490)	-	1436027..1436989 (-)	963	WP_198463284.1	Gfo/Idh/MocA family protein	-
I6I02_RS06495 (I6I02_06495)	-	1437089..1438324 (-)	1236	WP_198463285.1	aminoacyltransferase	-
I6I02_RS06500 (I6I02_06500)	-	1438302..1438985 (-)	684	WP_110980882.1	TVP38/TMEM64 family protein	-
I6I02_RS06505 (I6I02_06505)	-	1439068..1439688 (-)	621	WP_048675996.1	DUF3862 domain-containing protein	-

Sequence

Protein

• Length: 756 a.a.
• Molecular weight: 83973.05 Da
• Isoelectric Point: 5.0564

>NTDB_id=517364 I6I02_RS06475 WP_073687523.1 1432798..1435068(+) (clpE) [Streptococcus salivarius strain FDAARGOS_1045]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQNCYKIMKSDPENPLNQFNQTGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGNTQGPGRPGGPRQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGSVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAI
TAAAELSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
KQTIKDQDMPVITEKHIEAIVEQKTNIPVGDLKEKEQSQLLSLADDLKSHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEV
EKAHPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGATRENRTNSVLNQLGDFFSPEFMNRFD
GIIEFSALSKENLLTIVDLMLDNVNQRLANNGIHLSVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPN
EKDLKAVMTSKGHITIKSAKKAEKATQKAEAAKESD

Nucleotide

• Length: 2271 bp

>NTDB_id=517364 I6I02_RS06475 WP_073687523.1 1432798..1435068(+) (clpE) [Streptococcus salivarius strain FDAARGOS_1045]
ATGCTCTGTCAAAACTGTAACCTTAATGAAGCTAGTATTCATTTGTATACCAATGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAAAATTGTTATAAAATCATGAAATCTGACCCAGAGAACCCCCTTAATCAATTCAATCAAACTGGAGGTTCCA
ACTTCTTCGATGATTTCTTCAGCGACCTAAATAACTTCCGTTCTTCTAACGGTGATCTTCCAAATACACCTCCAACACAA
GAAGGTGGTAACCGAGGAAATGGTGGCAATACACAAGGGCCAGGCCGTCCAGGAGGACCACGCCAACAAGCTCCTCAACA
GCCACAAGGTCTTCTTGAAGAGTTCGGCATTAACATCACTGACATCGCTCGTCGTGGAGACATTGATCCTGTTATTGGTC
GTGACGAGGAAATCATTCGTGTCATCGAAATTCTTAACCGCCGTACCAAGAACAATCCCGTTCTCATCGGTGAACCCGGT
GTCGGTAAAACTGCTGTCGTTGAAGGACTAGCTCAAAAAATTGTAGATGGTAGCGTTCCTCAAAAACTCCAAGGCAAACA
AGTCATCCGTCTTGATGTGGTCAGCTTGGTTCAAGGAACTGGTATTCGTGGCCAATTTGAAGAACGCATGCAAAAACTCA
TGGAAGAAATTCGTCAACGTCAGGATGTTATCCTATTTATTGATGAAATCCATGAAATCGTAGGAGCTGGTAATGCTGGA
GATGGCAATATGGATGCTGGAAACATCTTAAAACCTGCCCTTGCTCGTGGGGAACTTCAACTGGTCGGAGCAACAACACT
CAACGAGTACCGCATCATCGAAAAAGATGCTGCCCTTGAGCGTCGTATGCAACCAGTTAAGGTTGACGAACCAACTGTTG
AGGAAACCATCACTATTTTACGTGGGATTCAGCCTAAATATCAAGACTACCACCACGTCAAATATACGGACGAAGCGATT
ACTGCAGCTGCAGAATTATCCAACCGCTACATTCAAGACCGTTTCTTACCAGACAAGGCCATCGACCTTCTTGATGAAGC
TGGTTCGAAGATGAACTTGACCCTCAACTTTGTTGATCCTAAAGATATCGACAAACGTTTGATTGAGGCTGAAAACCTCA
AGGCTCAAGCTACTCGTGACGAGGACTTTGAAAAGGCTGCCTATTTCCGTGACCAAATTGCCAAATACAAGGAAATGCAA
AAGCAAACCATCAAAGACCAAGATATGCCTGTCATCACCGAAAAACATATCGAAGCTATTGTGGAACAAAAAACCAATAT
TCCTGTCGGTGATTTGAAAGAAAAAGAACAATCACAACTTCTTAGTCTTGCCGATGATCTTAAATCACATGTTATCGGAC
AAGATGCTGCAGTTGATAAGATTGCTAAAGCTATCCGCCGTAATCGTGTTGGATTGGGTGCTCCAAACCGCCCAATTGGT
AGCTTCCTCTTCGTAGGTCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAATTGGCTATTGAACTCTTTGGTTCAGC
TGACAGTATGATTCGTTTCGATATGTCAGAATACATGGAAAAACACGCTGTCGCTAAATTGGTTGGTGCCCCTCCAGGAT
ATGTTGGTTACGACGAAGCTGGTCAGTTAACTGAAAAAGTCCGCCGTAATCCTTATTCACTTATTCTTTTAGATGAGGTT
GAAAAAGCTCACCCAGACGTTCTTCACATGTTCCTCCAAGTCCTTGACGACGGTCGTTTGACTGATGGTCAAGGACGCAC
TGTAAGCTTCAAGGATACCATCATCATCATGACCTCAAATGCTGGTACTGGTAAAGTTGAAGCTAGCGTTGGCTTTGGAG
CTACTCGTGAAAATCGTACCAATTCTGTTCTTAACCAACTTGGAGATTTCTTCAGTCCTGAATTCATGAACCGCTTTGAT
GGTATTATCGAATTCTCTGCCCTCAGCAAAGAAAATCTCCTTACTATCGTGGACCTCATGCTTGATAATGTCAACCAACG
CTTGGCTAACAACGGTATCCACCTCAGTGTAACTGAGAAAGTTAAGGAAAAATTGGTTGACCTTGGTTACGATCCTAAGA
TGGGTGCTCGACCACTACGTCGTACCATCCAAGATCACATTGAAGATGCTATTACCGACTTCTACCTTGAAAATCCAAAC
GAAAAAGATCTCAAGGCAGTCATGACTTCAAAAGGCCACATTACCATTAAGTCTGCTAAAAAAGCCGAAAAAGCTACTCA
AAAAGCTGAGGCAGCAAAAGAATCTGATTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (154-274)

• AAA domain (Cdc48 subfamily) (AAA_2) (477-640)

• AAA lid domain (AAA_lid_9) (292-390)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (648-721)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.771	99.471	0.853
clpE	Streptococcus pneumoniae Rx1	83.134	99.603	0.828
clpE	Streptococcus pneumoniae D39	83.134	99.603	0.828
clpE	Streptococcus pneumoniae R6	83.134	99.603	0.828
clpE	Streptococcus pneumoniae TIGR4	83.134	99.603	0.828
clpC	Lactococcus lactis subsp. cremoris KW2	78.718	96.958	0.763
clpC	Bacillus subtilis subsp. subtilis str. 168	51.852	85.714	0.444
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.037	86.772	0.399
clpC	Streptococcus pneumoniae Rx1	47.36	82.672	0.392
clpC	Streptococcus pneumoniae D39	47.36	82.672	0.392
clpC	Streptococcus pneumoniae TIGR4	47.2	82.672	0.39
clpC	Streptococcus thermophilus LMD-9	47.04	82.672	0.389
clpC	Streptococcus thermophilus LMG 18311	46.72	82.672	0.386
clpC	Streptococcus mutans UA159	46.228	82.407	0.381