Detailed information NTG0517201

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I6H73_RS10090
• Genome accession: NZ_CP066073
• Coordinates: 2014505..2016949 (-)
• Length: 814 a.a.
• NCBI ID: WP_003054754.1
• Uniprot ID: A0AAE9QRS9
• Organism: Streptococcus dysgalactiae strain FDAARGOS_1016
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2009505..2021949

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H73_RS10070 (I6H73_10070)	-	2009864..2011360 (+)	1497	WP_003054758.1	C69 family dipeptidase	-
I6H73_RS10075 (I6H73_10075)	-	2011693..2012160 (+)	468	WP_003054740.1	8-oxo-dGTP diphosphatase	-
I6H73_RS10080 (I6H73_10080)	groL	2012376..2014001 (-)	1626	WP_003054752.1	chaperonin GroEL	-
I6H73_RS10085 (I6H73_10085)	groES	2014037..2014327 (-)	291	WP_003054738.1	co-chaperone GroES	-
I6H73_RS10090 (I6H73_10090)	clpC	2014505..2016949 (-)	2445	WP_003054754.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I6H73_RS10095 (I6H73_10095)	-	2016949..2017410 (-)	462	WP_003054759.1	CtsR family transcriptional regulator	-
I6H73_RS10100 (I6H73_10100)	-	2017606..2017809 (-)	204	WP_003053018.1	cold-shock protein	-
I6H73_RS11655	-	2018367..2018915 (+)	549	WP_003054749.1	amidohydrolase family protein	-
I6H73_RS10110 (I6H73_10110)	-	2019230..2020672 (-)	1443	WP_115261945.1	IS1182 family transposase	-
I6H73_RS10120 (I6H73_10120)	ahpC	2021299..2021859 (+)	561	WP_003058719.1	alkyl hydroperoxide reductase subunit C	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90381.04 Da
• Isoelectric Point: 6.7391

>NTDB_id=517201 I6H73_RS10090 WP_003054754.1 2014505..2016949(-) (clpC) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MIMYSLKMQEIFRQAQFQAARFDSQYLETWHILLAMARVDHSLAGLVLSEFDAKVAVEEYEAAAILAMGKSPKYQVSHID
FRPQSKTLTNLLQFAQAISQVTKDQEVGSEHVLFAILLNPDIMATRLLEMAGYTIKDKGNGEPRLADLRKAIEIHAGYSK
EIIKAIHELRKPKKTKNQGSFSDMMKPPSTAGDLADFTRDLTEMASQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNVEDAYQILLGLKGSYETYHNVTIAN
QAVRTAVKMAHRYLTSKNLPDSAIDLLDEASATVQGMVKKSRPEIITPLDQALIDGDMKKASRLLAKDVKGQHRKPTAVT
EEDILTTLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGISHDHQAMEKRILEELKKAYRPEFINRIDEKVVFH
SLTQDNMREVVKIMVQPLMATLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGELASGHTL
KIGLSHGKLSFNLE

Nucleotide

• Length: 2445 bp

>NTDB_id=517201 I6H73_RS10090 WP_003054754.1 2014505..2016949(-) (clpC) [Streptococcus dysgalactiae strain FDAARGOS_1016]
ATGATCATGTATTCATTGAAGATGCAAGAAATTTTCAGGCAGGCGCAGTTTCAAGCAGCCCGCTTTGATAGCCAATACCT
AGAAACTTGGCATATATTGCTAGCTATGGCGAGGGTTGACCACTCCCTAGCGGGTTTGGTTCTAAGCGAATTTGATGCTA
AGGTTGCAGTGGAAGAATATGAGGCTGCAGCTATTTTAGCGATGGGCAAAAGTCCTAAATACCAAGTGTCTCACATTGAC
TTTAGGCCTCAGTCAAAAACCTTAACGAACCTTTTGCAATTTGCCCAAGCTATCAGTCAAGTCACCAAAGACCAAGAGGT
AGGTTCAGAGCATGTTCTCTTTGCCATTTTGCTTAATCCAGATATTATGGCTACTCGCTTATTAGAGATGGCGGGTTATA
CTATCAAGGATAAAGGAAACGGGGAGCCTCGCTTAGCTGATTTACGAAAAGCTATCGAGATTCATGCAGGCTATAGCAAG
GAAATAATTAAGGCTATCCACGAGTTGCGTAAGCCAAAGAAAACCAAAAATCAAGGTTCTTTTTCAGACATGATGAAGCC
ACCAAGCACGGCTGGGGACTTGGCGGACTTTACACGTGATTTGACCGAGATGGCAAGCCAAGGTCTCTTAGAGCCAGTTA
TTGGCCGTGATGCTGAAGTGTCACGGATGATTCAAGTACTGAGTCGTAAAACAAAGAATAACCCTGTTCTTGTGGGTGAT
GCAGGTGTGGGTAAAACGGCCCTTGCCTACGGGCTAGCCCAACGTATTGCTAATGGTGCTATTCCTTATGAGCTGCAAGA
CATGCGTGTTCTAGAATTAGACATGATGAGTGTTGTTGCGGGGACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGACGATATTGAGTCAGATGGCAAAATTATTCTCTTCGTAGATGAATTGCACACCATTATGGGATCAGGAAGT
GGTATTGATAGCACGCTTGATGCTGCCAATATTTTAAAACCAGCCTTATCTCGTGGAACCCTCCATATGGTGGGTGCAAC
AACGCAGGAAGAATACCAAAAACACATTGAAAAAGATGCCGCTCTTTCGCGCCGCTTTGCTAAGATTTTAATTGAAGAAC
CTAATGTAGAAGATGCTTATCAGATTCTGCTAGGACTAAAAGGCTCTTACGAGACTTACCATAATGTGACCATTGCTAAT
CAGGCTGTTAGAACCGCTGTGAAAATGGCACATCGCTATCTGACCAGCAAAAACCTTCCGGATTCTGCCATTGATTTGTT
GGATGAAGCCAGTGCTACAGTGCAAGGTATGGTTAAAAAATCTAGGCCAGAAATCATCACGCCATTAGATCAAGCTTTGA
TTGATGGCGATATGAAGAAGGCCTCTCGTTTGTTGGCAAAAGACGTTAAAGGGCAACATCGCAAGCCAACAGCTGTGACA
GAAGAGGACATCCTGACGACCTTGAGCAAGCTATCAGGTATTCCACTGGAAAAACTCAGCCAAGCTGATAGCAAAAAATA
CCTTAATTTGGAAAAAGAACTGCATAAGCGCGTGATTGGGCAAGAAGATGCTGTCTCAGCTATTTCTAGAGCCATTCGCC
GTAATCAGTCAGGCATTCGTACAGGTAAACGTCCAATCGGTTCTTTCATGTTCCTTGGTCCAACAGGGGTTGGTAAGACC
GAGTTGGCAAAAGCCTTGGCAGAAGTTCTCTTTGATGACGCGTCCGCCCTTATCCGCTTTGATATGTCAGAGTATATGGA
GAAATTTGCGGCTTCTCGCCTTAATGGCGCACCTCCAGGCTATGTTGGTTACGATGAAGGTGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTATTCTGTGCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAACGTCCTCTTACAA
GTGCTTGATGATGGCATGTTGACAGATAGCCGTGGGCGTAAAGTGGACTTCTCAAATACCATTATTATCATGACAAGTAA
TCTAGGGGCAACAGCTCTGCGTGATGATAAAACAGTTGGCTTTGGGGCAAAAGGCATTAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAAAAAGCTTACCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAC
AGCCTCACTCAGGACAATATGAGAGAAGTAGTCAAGATTATGGTGCAGCCGTTGATGGCTACTTTGGCAGAAAAAGGCAT
TACCCTCAAATTCCAGCCAATGGCCCTCAAGTATTTATCAGAAGAAGGGTATGATGTGGAAATGGGTGCTCGTCCATTAC
GCCGCACTTTGCAAACTCAGGTGGAAGATAAATTGTCTGAATTGATTCTTGCTGGTGAATTGGCAAGTGGTCATACCCTG
AAAATTGGCCTTTCTCATGGAAAACTCAGCTTTAACCTTGAGTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (376-462)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-137)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.507	99.877	0.764
clpC	Streptococcus thermophilus LMD-9	72.794	100	0.73
clpC	Streptococcus thermophilus LMG 18311	72.794	100	0.73
clpC	Streptococcus pneumoniae TIGR4	67.159	99.877	0.671
clpC	Streptococcus pneumoniae Rx1	67.159	99.877	0.671
clpC	Streptococcus pneumoniae D39	67.159	99.877	0.671
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.681	100	0.499
clpC	Bacillus subtilis subsp. subtilis str. 168	42.84	100	0.437