Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   I6H74_RS08755 Genome accession   NZ_CP066069
Coordinates   1799237..1801528 (+) Length   763 a.a.
NCBI ID   WP_048327413.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1794237..1806528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS08730 (I6H74_08725) feoB 1794328..1796486 (-) 2159 Protein_1670 ferrous iron transport protein B -
  I6H74_RS08735 (I6H74_08730) - 1796483..1796962 (-) 480 WP_003056958.1 ferrous iron transport protein A -
  I6H74_RS08740 (I6H74_08735) - 1797161..1797895 (-) 735 WP_015017221.1 amino acid ABC transporter ATP-binding protein -
  I6H74_RS08745 (I6H74_08740) - 1797895..1798581 (-) 687 WP_003051835.1 amino acid ABC transporter permease -
  I6H74_RS08750 (I6H74_08745) - 1798709..1798939 (-) 231 WP_003051836.1 DUF1797 family protein -
  I6H74_RS08755 (I6H74_08750) clpE 1799237..1801528 (+) 2292 WP_048327413.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  I6H74_RS08760 (I6H74_08755) - 1801646..1802101 (+) 456 WP_003059823.1 NUDIX hydrolase -
  I6H74_RS08765 (I6H74_08760) - 1802151..1802453 (+) 303 WP_046176950.1 DUF1827 family protein -
  I6H74_RS08770 (I6H74_08765) ileS 1802856..1805657 (-) 2802 WP_046176951.1 isoleucine--tRNA ligase -

Sequence

Protein


Download         Length: 763 a.a.        Molecular weight: 84955.26 Da        Isoelectric Point: 5.3453

>NTDB_id=517113 I6H74_RS08755 WP_048327413.1 1799237..1801528(+) (clpE) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MLCQNCNLNESTIHLYTNVNGKQKQVDLCQNCYQIMKTDPTNPILGGLNGGQRAQERSSNPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRHGGHFNGQRPTQPQTPNQQAKGLLEEFGINVTDIARHGDIDPVIGRDDEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIVDGTVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
IAKFKEMQAQKVDEQDIPIITEKTIEAIIEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKDNLLHIVDLMLEDVNKRLSYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKDLRAIMTSNSNIMIKAAKKDETVTAKQDKTDEN

Nucleotide


Download         Length: 2292 bp        

>NTDB_id=517113 I6H74_RS08755 WP_048327413.1 1799237..1801528(+) (clpE) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGCTTTGTCAAAATTGTAATTTAAACGAATCAACCATTCACCTCTACACGAATGTTAATGGAAAACAAAAACAAGTTGA
CCTTTGTCAAAACTGTTATCAAATCATGAAGACTGACCCTACTAATCCTATTTTAGGTGGCCTAAATGGAGGTCAAAGAG
CCCAAGAACGCTCATCCAACCCCTTCTTTGATGACTTTTTTGGGGACTTAAATAATTTTAGAGCCTTTGGCAACCTTCCA
AATACCCCACCTACTCAGGCAGGGCAAAATGGAAATGGTGGGGGACGCCATGGTGGTCATTTCAATGGACAACGTCCCAC
TCAGCCACAAACACCAAATCAGCAAGCAAAAGGCTTGCTAGAAGAATTTGGCATTAATGTGACCGATATTGCAAGACATG
GTGATATTGACCCTGTCATCGGTCGAGATGACGAGATTACACGTGTCATTGAAATCCTTAACCGTCGGACTAAAAATAAC
CCTGTGCTTATTGGGGAACCAGGAGTTGGTAAAACAGCTGTTGTAGAAGGTCTAGCCCAAAAAATTGTAGATGGCACAGT
ACCTCACAAATTGCAAGGTAAGCAAGTGATCCGTCTAGATGTGGTTAGTCTTGTTCAAGGCACAGGTATCCGTGGTCAAT
TCGAAGAACGCATGCAAAAATTAATGGAAGAAATTCGTCAACGCAAAGATGTGATTCTCTTTATTGATGAAATTCATGAA
ATTGTAGGTGCTGGTTCTGCTGGAGATGGCAATATGGATGCTGGCAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACCTTAAATGAATACCGTATTATTGAAAAAGATGCTGCCTTGGAGCGGCGGATGCAGCCGG
TGAAAGTTGACGAACCTTCTGTAGAAGAAACCATTACCATCTTAAAAGGTATCCAACCCAAATATGAAGACTATCATCAT
GTCAAATATAGCCCAGCAGCTATCGAGGCTGCTGCACACTTATCCAATCGCTACATCCAAGACCGATTCCTCCCTGATAA
GGCCATTGACCTTCTGGACGAAGCTGGTTCAAAAATGAATTTAACTCTTAATTTTGTTGACCCTAAAGAGATTGACAAAC
GTCTGATTGAAGCAGAAAACCTCAAAGCTCAAGCAACTCGTGACGAAGATTACGAACGAGCAGCCTATTTCCGTGATCAA
ATTGCGAAATTCAAGGAAATGCAAGCTCAAAAAGTCGACGAACAGGATATTCCTATCATTACTGAAAAAACCATTGAAGC
CATCATTGAACAAAAAACCAATATTCCAGTTGGCGACTTGAAAGAAAAAGAACAATCTCAACTCGTTAATTTGGCTAATG
ATTTGAAAGCTCACGTGATTGGCCAAGATGATGCCGTTGACAAAATTGCCAAGGCCATTCGCCGGAACCGTGTGGGATTG
GGAACTCCAAATCGTCCTATTGGTTCTTTCCTATTCGTTGGGCCAACAGGTGTTGGTAAAACAGAGTTGTCTAAGCAACT
AGCTATTGAACTCTTTGGCTCTGCTGACAATATGATTCGCTTTGATATGTCCGAATACATGGAAAAACATGCCGTTGCTA
AATTAGTCGGGGCTCCTCCTGGTTATGTGGGCTATGAAGAAGCTGGCCAGTTAACGGAACAAGTTCGCCGCAACCCATAT
TCACTTATTCTCTTAGATGAGGTGGAAAAGGCTCATCCTGACGTCATGCACATGTTTTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGGACAGTCAGCTTCAAGGATACTATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GCGAAGCTTCTGTTGGATTTGGTGCAGCTAGAGAAGGACGAACAAGCTCTGTCCTTGGTGAATTAAGTAACTTCTTCAGC
CCAGAGTTCATGAACCGTTTCGATGGTATTATTGAATTTAAGGCCTTGAGCAAAGATAACCTCTTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATAAGCGCTTAAGCTATAATGGGATTCACCTTGATGTGACACAAAAAGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGTGCTCGACCACTCCGTCGTACCATCCAAGATTATATCGAAGATGCGATTACG
GACTACTATTTGGAACACCCCACTGAAAAGGACTTGCGTGCCATAATGACAAGTAACAGTAATATCATGATTAAAGCTGC
CAAAAAAGATGAAACGGTAACAGCTAAACAAGATAAGACCGACGAGAACTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(656-730)

AAA domain (Cdc48 subfamily) (AAA_2)

(485-648)

AAA lid domain (AAA_lid_9)

(300-397)

ATPase family associated with various cellular activities (AAA) (AAA)

(162-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.45

99.083

0.847
  clpE Streptococcus pneumoniae Rx1

84.058

99.476

0.836
  clpE Streptococcus pneumoniae D39

84.058

99.476

0.836
  clpE Streptococcus pneumoniae R6

84.058

99.476

0.836
  clpE Streptococcus pneumoniae TIGR4

83.926

99.476

0.835
  clpC Lactococcus lactis subsp. cremoris KW2

76.495

96.461

0.738
  clpC Bacillus subtilis subsp. subtilis str. 168

51.138

86.37

0.442
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.615

85.19

0.397
  clpC Streptococcus pneumoniae TIGR4

48

81.913

0.393
  clpC Streptococcus pneumoniae Rx1

48

81.913

0.393
  clpC Streptococcus pneumoniae D39

48

81.913

0.393
  clpC Streptococcus mutans UA159

47.573

80.996

0.385
  clpC Streptococcus thermophilus LMD-9

46.955

81.782

0.384
  clpC Streptococcus thermophilus LMG 18311

46.635

81.782

0.381