Detailed information NTG0517089

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I6H74_RS02330
• Genome accession: NZ_CP066069
• Coordinates: 441116..443560 (+)
• Length: 814 a.a.
• NCBI ID: WP_115257058.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain FDAARGOS_1017
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 436116..448560

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H74_RS02305 (I6H74_02300)	-	437315..437770 (-)	456	WP_046177586.1	MarR family transcriptional regulator	-
I6H74_RS02310 (I6H74_02305)	-	437806..438669 (-)	864	WP_046177583.1	IS982 family transposase	-
I6H74_RS02315 (I6H74_02310)	-	438871..439698 (-)	828	WP_115257059.1	amidohydrolase family protein	-
I6H74_RS02320 (I6H74_02315)	-	440256..440459 (+)	204	WP_003053018.1	cold-shock protein	-
I6H74_RS02325 (I6H74_02320)	-	440655..441116 (+)	462	WP_003054759.1	CtsR family transcriptional regulator	-
I6H74_RS02330 (I6H74_02325)	clpC	441116..443560 (+)	2445	WP_115257058.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I6H74_RS02335 (I6H74_02330)	groES	443738..444028 (+)	291	WP_003054738.1	co-chaperone GroES	-
I6H74_RS02340 (I6H74_02335)	groL	444064..445689 (+)	1626	WP_012767614.1	chaperonin GroEL	-
I6H74_RS02345 (I6H74_02340)	-	445906..446373 (-)	468	WP_003060031.1	8-oxo-dGTP diphosphatase	-
I6H74_RS02350 (I6H74_02345)	-	446706..448202 (-)	1497	WP_115257057.1	C69 family dipeptidase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90325.96 Da
• Isoelectric Point: 6.6501

>NTDB_id=517089 I6H74_RS02330 WP_115257058.1 441116..443560(+) (clpC) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MIMYSLKMQEIFRQAQFQAARFDSQYLETWHILLAMARVDHSLAGLVLSEFDAKVAVEEYEAAAILAMGKSPKYQVSHID
FRPQSKTLTNLLQFAQAISQVTKDQEVGSEHVLFAILLNPDIMATRLLEMAGYTIKDKGNGEPRLADLRKAIEIHAGYSK
EIIKAIHELRKPKKTKNQGSFSDMMKPPSTAGDLADFTRDLTEMASQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNVEDAYQILLGLKGSYETYHNVTIAN
QAVRTAVKMAHRYLTSKNLPDSAIDLLDEASATVQGMVKKSTPEIITPLDQALIDGDMKKASRLLAKDVKGQHRKPTAVT
EEDILTTLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGISHDHQAMEKRILEELKKAYRPEFINRIDEKVVFH
SLTQDNMREVVKIMVQPLMATLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGELASGHTL
KIGLSHGKLSFNLE

Nucleotide

• Length: 2445 bp

>NTDB_id=517089 I6H74_RS02330 WP_115257058.1 441116..443560(+) (clpC) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGATCATGTATTCATTGAAGATGCAAGAAATTTTCAGGCAGGCGCAGTTTCAAGCAGCCCGCTTTGATAGCCAATACCT
AGAAACTTGGCATATATTGCTAGCTATGGCGAGGGTTGACCACTCCCTAGCGGGTTTGGTGCTAAGCGAATTTGATGCTA
AGGTTGCAGTGGAAGAATATGAGGCTGCAGCTATTTTAGCGATGGGCAAAAGTCCTAAATACCAAGTGTCTCACATTGAC
TTTAGGCCTCAGTCAAAAACCTTAACGAACCTTTTGCAATTTGCCCAAGCTATCAGTCAAGTCACCAAAGACCAAGAGGT
AGGTTCAGAGCATGTTCTCTTTGCCATTTTGCTTAATCCAGATATTATGGCTACTCGCTTATTAGAGATGGCGGGTTATA
CTATCAAGGATAAAGGAAACGGGGAGCCTCGCTTAGCTGATTTACGAAAAGCTATCGAGATTCATGCAGGCTATAGCAAG
GAAATAATTAAGGCTATCCACGAGTTGCGTAAGCCAAAGAAAACCAAAAATCAAGGTTCTTTTTCAGACATGATGAAGCC
ACCAAGCACGGCTGGGGACTTGGCGGACTTTACACGTGATTTGACCGAGATGGCAAGCCAAGGTCTCTTAGAGCCAGTTA
TTGGCCGTGATGCTGAAGTGTCACGGATGATTCAAGTACTGAGTCGTAAAACAAAGAATAACCCTGTTCTTGTGGGTGAT
GCAGGTGTGGGTAAAACGGCCCTTGCCTACGGCCTAGCCCAACGTATTGCTAATGGTGCTATTCCTTATGAGCTGCAAGA
CATGCGTGTTCTAGAATTAGACATGATGAGTGTTGTTGCGGGGACCCGTTTCCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGACGATATTGAGTCAGATGGCAAAATTATTCTCTTCGTAGATGAATTGCACACCATTATGGGATCAGGAAGT
GGTATTGATAGCACGCTTGATGCTGCCAATATTTTAAAACCAGCCTTATCTCGTGGAACCCTCCATATGGTGGGTGCAAC
AACGCAGGAAGAATACCAAAAACACATTGAAAAAGATGCCGCTCTTTCGCGCCGCTTTGCTAAGATTTTAATTGAAGAAC
CTAATGTAGAAGATGCTTATCAGATTCTGCTAGGACTAAAAGGCTCTTACGAGACTTACCATAATGTGACCATTGCTAAT
CAGGCTGTTAGAACCGCTGTGAAAATGGCACATCGCTATCTGACCAGCAAAAACCTTCCGGATTCTGCCATTGATTTGTT
GGATGAAGCCAGTGCTACAGTGCAAGGTATGGTTAAAAAATCTACGCCAGAAATCATCACGCCATTAGATCAAGCTTTGA
TTGATGGCGATATGAAGAAGGCCTCTCGTTTGTTGGCAAAAGACGTTAAAGGGCAACATCGCAAGCCAACAGCTGTGACA
GAAGAGGACATCCTGACGACCTTGAGCAAGCTATCAGGTATTCCACTGGAAAAACTCAGCCAAGCTGATAGCAAAAAATA
CCTTAATTTGGAAAAAGAACTGCATAAGCGCGTGATTGGGCAAGAAGATGCTGTCTCAGCTATTTCTAGAGCCATTCGCC
GTAATCAGTCAGGCATTCGTACAGGTAAACGTCCAATCGGTTCTTTCATGTTCCTTGGTCCAACAGGGGTTGGTAAGACC
GAGTTGGCAAAAGCCTTGGCAGAAGTTCTCTTTGATGACGCGTCCGCCCTTATCCGCTTTGATATGTCAGAGTATATGGA
GAAATTTGCGGCTTCTCGCCTTAATGGCGCACCTCCAGGCTATGTTGGTTACGATGAAGGTGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTATTCTGTGCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAACGTCCTCTTACAA
GTGCTTGATGATGGCATGTTGACAGATAGCCGTGGGCGTAAAGTGGACTTCTCAAATACCATTATTATCATGACAAGTAA
TCTAGGGGCAACAGCTCTGCGTGATGATAAAACAGTTGGCTTTGGGGCAAAAGGCATTAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAAAAAGCTTACCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAC
AGCCTCACTCAGGACAATATGAGAGAAGTAGTCAAGATTATGGTGCAGCCGTTGATGGCTACTTTGGCAGAAAAAGGCAT
TACCCTCAAATTCCAGCCAATGGCCCTCAAGTATTTATCAGAAGAAGGGTATGATGTGGAAATGGGTGCTCGTCCATTAC
GCCGCACTTTGCAAACTCAGGTGGAAGATAAATTGTCTGAATTGATTCTTGCTGGTGAATTGGCAAGTGGTCATACCCTG
AAAATTGGCCTTTCTCATGGAAAACTCAGCTTTAACCTTGAGTGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• AAA lid domain (AAA_lid_9) (376-462)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-137)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.507	99.877	0.764
clpC	Streptococcus thermophilus LMG 18311	72.794	100	0.73
clpC	Streptococcus thermophilus LMD-9	72.794	100	0.73
clpC	Streptococcus pneumoniae TIGR4	67.159	99.877	0.671
clpC	Streptococcus pneumoniae Rx1	67.159	99.877	0.671
clpC	Streptococcus pneumoniae D39	67.159	99.877	0.671
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.681	100	0.499
clpC	Bacillus subtilis subsp. subtilis str. 168	42.788	100	0.437