Detailed information NTG0516975

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I6H78_RS05620
• Genome accession: NZ_CP066059
• Coordinates: 1158935..1161367 (+)
• Length: 810 a.a.
• NCBI ID: WP_198459059.1
• Uniprot ID: A0A7T4IRD0
• Organism: Streptococcus oralis strain FDAARGOS_1021
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1153935..1166367

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H78_RS05610 (I6H78_05610)	-	1154836..1158303 (+)	3468	WP_416069067.1	Spy0128 family protein	-
I6H78_RS05615 (I6H78_05615)	-	1158475..1158933 (+)	459	WP_198459058.1	CtsR family transcriptional regulator	-
I6H78_RS05620 (I6H78_05620)	clpC	1158935..1161367 (+)	2433	WP_198459059.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I6H78_RS05625 (I6H78_05625)	-	1161520..1162578 (+)	1059	WP_198459060.1	AAA family ATPase	-
I6H78_RS05630 (I6H78_05630)	pnuC	1162588..1163367 (+)	780	WP_198459061.1	nicotinamide riboside transporter PnuC	-
I6H78_RS05635 (I6H78_05635)	-	1163369..1164142 (+)	774	WP_198459062.1	NUDIX domain-containing protein	-
I6H78_RS05640 (I6H78_05640)	-	1164415..1165098 (+)	684	WP_198459063.1	hypothetical protein	-
I6H78_RS05645 (I6H78_05645)	dusB	1165165..1166145 (-)	981	WP_198459064.1	tRNA dihydrouridine synthase DusB	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 90374.31 Da
• Isoelectric Point: 6.2577

>NTDB_id=516975 I6H78_RS05620 WP_198459059.1 1158935..1161367(+) (clpC) [Streptococcus oralis strain FDAARGOS_1021]
MNYSKALNECIESAYMVASHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLEVLFAEAEYVASVVHAKVLGTEHVLYAILHDGNALATRILERAGFSYEDQKDQVRIAALRRNLEERAGWTREDLKA
LRQRHRTVTDKQNSMANMMGMPQAQSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGKVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSMADSITILQGLKATYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADESDLTPADKALMDGKWKQAAQLIAKEQEVPVYKDLVTESEI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQKNMEKRIFEELKKTYRPEFINRIDEKVVFHSLDS
KHMQEIIKIMVKPLIASLAEKGIDLKLQASALKLLASQGYDPEMGARPLRRTLQTEVEDKLAELLLKGELVAGKTLKIGV
KAGQLKFDIA

Nucleotide

• Length: 2433 bp

>NTDB_id=516975 I6H78_RS05620 WP_198459059.1 1158935..1161367(+) (clpC) [Streptococcus oralis strain FDAARGOS_1021]
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAGAGTGCCTACATGGTTGCGAGCCATTTTGGAGCCCGTTACCTAGA
GTCTTGGCATTTATTGATTGCCATGTCCAATCACAGTTACAGTGTGGCAGGTGCAACTCTAAATGATTATCCTTATGAAA
TGGATCGTTTAGAAGAGGTTGCGTTGGAACTGACTGAAACGGATTATAGCCAAGACGAAACTTTTACGGAATTGCCCTTT
TCCCATCGTTTAGAAGTTCTCTTTGCAGAAGCAGAGTATGTAGCCTCAGTGGTCCACGCAAAGGTGCTAGGGACAGAACA
TGTCCTCTATGCGATCTTGCATGACGGCAATGCCTTGGCAACTCGCATCTTGGAGAGAGCAGGCTTTTCTTATGAAGACC
AGAAAGATCAGGTCAGAATTGCTGCTCTTCGTCGTAATCTAGAAGAGCGTGCAGGATGGACAAGAGAAGATCTCAAGGCT
TTGCGTCAACGTCATCGCACAGTAACTGATAAGCAAAATTCTATGGCCAATATGATGGGCATGCCTCAAGCTCAAAGTGG
TGGTCTAGAGGACTACACGCATGACCTAACGGAGCAAGCGCGTTCTGGCAAGTTAGAGCCAGTTATAGGTCGAGACAAGG
AAATCTCACGTATGATTCAGATTTTGAGTCGGAAGACCAAGAACAATCCGGTCTTGGTTGGAGATGCGGGTGTCGGGAAA
ACAGCTCTGGCACTTGGTCTTGCTCAGCGTATTGCTAGTGGGGATGTACCTGCGGAAATGGCAAAGATGCGCGTTTTGGA
GCTTGATTTGATGAATGTTGTTGCGGGGACACGTTTCCGTGGAGATTTTGAAGAGCGTATGAACAATATCATCAAGGATA
TCGAGGAAGATGGCAAAGTAATCCTCTTTATCGATGAACTCCACACCATCATGGGTTCTGGTAGCGGTATTGACTCGACT
CTGGATGCAGCTAATATCTTGAAACCAGCCTTGGCTCGTGGAACTTTGAGAACGGTTGGTGCAACCACTCAGGAAGAATA
CCAAAAACACATCGAAAAAGATGCTGCCCTTTCTCGTCGGTTTGCCAAAGTGACGATTGAAGAGCCTAGTATGGCAGATA
GTATAACCATTTTGCAAGGTTTGAAGGCTACCTATGAGAAACATCACCGTGTGCAAATCACAGATGAAGCTGTTGAAACA
GCTGTTAAGATGGCGCATCGTTACTTAACTAGTCGTCACTTGCCAGACTCTGCTATCGACCTCTTGGATGAAGCGGCAGC
AACAGTGCAAAACAAATCCAAGCATGTGAAAGCAGACGAATCCGACTTGACTCCAGCTGACAAGGCCCTGATGGATGGCA
AGTGGAAACAAGCTGCCCAGCTAATCGCAAAGGAGCAGGAAGTCCCTGTCTATAAAGACTTGGTAACAGAATCTGAAATT
TTGACTACCTTGAGTCGCTTGTCAGGTATCCCAGTCCAAAAACTGACGCAAACGGATGCCAAGAAATACCTTAATTTGGA
AGCGGAACTGCACAAACGTGTCATTGGCCAAGATCAAGCTGTTTCAAGCATTAGCCGTGCCATTCGCCGCAACCAGTCAG
GAATTCGTAGTCACAAGCGTCCGATTGGTTCCTTTATGTTCCTAGGGCCGACAGGAGTCGGTAAGACCGAATTGGCAAAG
GCTCTGGCAGAAGTCCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTCGCAGC
TAGCCGTCTCAATGGAGCACCTCCTGGCTATGTGGGCTACGAGGAAGGTGGGGAGTTGACCGAGAAAGTTCGCAACAAAC
CATACTCTGTACTCCTCTTTGACGAGGTAGAGAAGGCCCACCCAGACATCTTTAATGTCCTCTTGCAAGTCTTGGACGAC
GGTGTCTTGACAGATAGCAAGGGACGCAAGGTTGACTTTTCAAATACCATTATCATCATGACGTCAAACCTTGGTGCGAC
AGCCCTTCGTGATGACAAGACTGTTGGCTTTGGTGCTAAAGACATTCGTTTTGACCAGAAAAATATGGAAAAACGAATCT
TTGAAGAGTTGAAAAAAACTTATCGACCAGAGTTTATCAACCGTATTGATGAAAAGGTGGTCTTCCACAGCTTAGATAGC
AAACACATGCAAGAAATTATCAAGATTATGGTTAAACCATTGATTGCTAGCCTGGCAGAGAAGGGCATCGACTTGAAACT
GCAAGCTTCAGCGTTGAAGTTACTAGCAAGCCAAGGATATGATCCAGAAATGGGAGCTCGCCCACTTCGCAGAACACTGC
AAACAGAAGTGGAAGACAAGTTGGCAGAACTCCTCCTTAAGGGAGAACTGGTAGCAGGCAAGACCCTCAAGATTGGTGTC
AAAGCAGGTCAGTTAAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (371-446)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (718-797)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (103-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-49)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-362)

• AAA domain (Cdc48 subfamily) (AAA_2) (540-711)

3D structure

• AlphaFold DB: A0A7T4IRD0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae D39	96.296	100	0.963
clpC	Streptococcus pneumoniae TIGR4	96.296	100	0.963
clpC	Streptococcus pneumoniae Rx1	96.296	100	0.963
clpC	Streptococcus mutans UA159	67.651	100	0.679
clpC	Streptococcus thermophilus LMD-9	67.199	100	0.675
clpC	Streptococcus thermophilus LMG 18311	67.076	100	0.674
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.396	100	0.505
clpC	Bacillus subtilis subsp. subtilis str. 168	45.197	100	0.453
clpE	Streptococcus mutans UA159	48.71	76.543	0.373