Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   I6I31_RS11400 Genome accession   NZ_CP066042
Coordinates   2325637..2326671 (-) Length   344 a.a.
NCBI ID   WP_115313031.1    Uniprot ID   A0A380H3R0
Organism   Staphylococcus saccharolyticus strain FDAARGOS_1074     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2320637..2331671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I31_RS11370 (I6I31_11370) - 2320980..2322221 (-) 1242 WP_115313037.1 aminopeptidase -
  I6I31_RS11375 (I6I31_11375) - 2322233..2322439 (-) 207 WP_115313036.1 DUF1128 domain-containing protein -
  I6I31_RS11380 (I6I31_11380) - 2322580..2323044 (+) 465 WP_115313035.1 low molecular weight protein-tyrosine-phosphatase -
  I6I31_RS11385 (I6I31_11385) - 2323051..2323335 (+) 285 WP_115313034.1 YtxH domain-containing protein -
  I6I31_RS11390 (I6I31_11390) - 2323692..2324948 (+) 1257 WP_115313033.1 YihY/virulence factor BrkB family protein -
  I6I31_RS11395 (I6I31_11395) vraR 2325006..2325635 (-) 630 WP_115313032.1 two-component system response regulator VraR Regulator
  I6I31_RS11400 (I6I31_11400) vraS 2325637..2326671 (-) 1035 WP_115313031.1 sensor histidine kinase Regulator
  I6I31_RS11405 (I6I31_11405) liaF 2326668..2327369 (-) 702 WP_115313030.1 cell wall-active antibiotics response protein LiaF -
  I6I31_RS11410 (I6I31_11410) - 2327384..2327764 (-) 381 WP_115313029.1 hypothetical protein -
  I6I31_RS11415 (I6I31_11415) map 2327895..2328650 (-) 756 WP_115313028.1 type I methionyl aminopeptidase -
  I6I31_RS11420 (I6I31_11420) - 2328827..2329816 (+) 990 WP_115313027.1 aromatic acid exporter family protein -
  I6I31_RS11425 (I6I31_11425) - 2329893..2330444 (-) 552 WP_115313026.1 hypothetical protein -
  I6I31_RS11430 (I6I31_11430) - 2330670..2331395 (-) 726 WP_115313025.1 type 1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39791.31 Da        Isoelectric Point: 6.5082

>NTDB_id=516713 I6I31_RS11400 WP_115313031.1 2325637..2326671(-) (vraS) [Staphylococcus saccharolyticus strain FDAARGOS_1074]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNILIILLCIIVGTVLAYKINQQNTWIKS
QIERSIEGETVGINNQNLELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKEEYLLLRIQDNGKGFNVHEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEEE

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=516713 I6I31_RS11400 WP_115313031.1 2325637..2326671(-) (vraS) [Staphylococcus saccharolyticus strain FDAARGOS_1074]
ATGAATCACTATCTAAGAGCTATTGGTTCTATGCTTATACTTGTTTATAGTATGCTCACTGCTTTTTTATTTATTGATAA
GGTTTTTGTTAATATTATCTATTTTCAAGGTATGTTTTATACTCAAATCTTTGGAATTCCTGTATTTTTATTTTTAAATA
TATTAATTATTTTACTATGTATTATAGTTGGAACAGTATTAGCGTATAAAATTAATCAACAAAATACGTGGATAAAATCC
CAAATTGAAAGGTCTATTGAGGGAGAGACTGTAGGTATTAATAATCAAAATTTAGAGTTATATAGTGAAACTTTAGAGAT
TTACCATACTTTAGTACCATTAAATCAAGAGTTACATCGTCTTAGAATGAAAACGCAAAATCTGACAAATGAAAATTATA
ATATTAATGATGTGAAAGTGAAAAAAATAATAGAAGATGAACGTCAACGTCTGGCGAGAGAATTGCATGACTCAGTGAGT
CAGCAATTATTCGCTGCAAGCATGATGTTATCTGCTATTAAAGAATCAAAGTTAGAACCTCCACTGGATCAACAAATTCC
TGTTCTAGAAAAAATGGTTCAAGATTCACAACTTGAGATGAGAGCGTTGCTTTTACATTTAAGACCAATTGGTTTAAAGG
ATAAGTCATTAGGTGAAGGTATTAAAGATTTAGTGATTGATCTTCAAAAGAAAGTTCCTATGAAAGTAGTACATGAAATC
CAAGATTTTGAGGTGCCTAAAGGCATTGAGGACCATTTATTTAGAATTACACAAGAAGCCATTTCTAATACATTGAGACA
TTCAAATGGCACGAAGGTGACTGTTGAATTATTTAATAAAGAAGAGTATTTATTGTTAAGAATACAAGATAATGGCAAAG
GCTTTAATGTACATGAAAAGTTTGAACAAAGTTATGGTTTAAAAAACATGAGAGAACGTGCTTTAGAAATCGGTGCAACG
TTTCATATCGTATCTTTGCCTGATTCCGGTACGCGAATAGAAGTGAAAGCACCATTGAATAAGGAGGAAGAGTAA

Domains

Predicted by InterproScan.

Histidine kinase (HisKA_3)

(147-210)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380H3R0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

92.711

99.709

0.924