Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   KW2_RS08025 Genome accession   NC_022369
Coordinates   1698791..1701121 (-) Length   776 a.a.
NCBI ID   WP_021037597.1    Uniprot ID   -
Organism   Lactococcus cremoris subsp. cremoris KW2     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1693791..1706121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KW2_RS07995 (kw2_1606) - 1694343..1695326 (-) 984 WP_021037595.1 LacI family DNA-binding transcriptional regulator -
  KW2_RS08000 (kw2_1607) purB 1695461..1696756 (-) 1296 WP_011676545.1 adenylosuccinate lyase -
  KW2_RS08005 (kw2_1608) aroD 1696971..1697660 (-) 690 WP_021037596.1 type I 3-dehydroquinate dehydratase -
  KW2_RS08015 (kw2_1610) - 1697933..1698136 (-) 204 WP_011676547.1 DUF2969 family protein -
  KW2_RS08020 (kw2_1611) trxA 1698380..1698694 (-) 315 WP_003129442.1 thioredoxin -
  KW2_RS08025 (kw2_1612) mutS/mutS2 1698791..1701121 (-) 2331 WP_021037597.1 endonuclease MutS2 Machinery gene
  KW2_RS08030 (kw2_1613) - 1701165..1701725 (-) 561 WP_011834758.1 CvpA family protein -
  KW2_RS08035 (kw2_1614) - 1702023..1702988 (-) 966 WP_021037598.1 NAD(P)/FAD-dependent oxidoreductase -
  KW2_RS08040 (kw2_1615) ccpA 1703122..1704120 (-) 999 WP_014572279.1 catabolite control protein A Regulator
  KW2_RS08045 (kw2_1616) - 1704334..1705422 (+) 1089 WP_011834755.1 M24 family metallopeptidase -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87444.35 Da        Isoelectric Point: 6.7299

>NTDB_id=51671 KW2_RS08025 WP_021037597.1 1698791..1701121(-) (mutS/mutS2) [Lactococcus cremoris subsp. cremoris KW2]
MNKKILQILEYDKVKEQFMNALTTAQGQKELSDLVPLTDKDKIQLLFDEVADFRLLTQENGLLNLGKTNDLTEILRRLEL
EASLSGKEFVEIKKVIQLGINIQRFFDEAENVETPSLNITLEKLVDLSGLIKKLEIFDNAGSLYDNASLELMHIRASIKS
HQSEIRKIMQEMLTKNLSSLSENVITIRNDRQVLPVKAENKNKIAGVVHDMSASGQTLYIEPNAVVSLNNKLNQKRIEER
QEITRIYRELAEELKPYSFDIRQNAWLIGHIDFVRAKYLYLTANKASLPALTHDKDIILFAARHPLIDAKMVVANDIKFD
RTLNTIVITGPNTGGKTITLKTVGLLTILAQSGLPILADDGSRIHLFDDIFADIGDEQSIEQSLSTFSSHMTNIVQILAQ
ADENSLVLFDELGAGTDPKEGAALAIAILENLRKRNVKTMASTHYPELKAYGVETQQVINASMEFNIDKMQPTYHLQLGV
PGRSNALEISRRLGLPETIISEASQQISESEHDVNQMIEKLEEKTREVIESSRNIKKIERENQSLHKDLTKVYNQINRER
DFELEKAQKEAQEVVKKASLEAQEILKNLNDKAALKPHEIIAARKELEGLAPTIDFSKNKVLKKAKAQRGLKQGAEVNVT
SYGQRGKLIRLEKDGRWTVQMGSITTRLSEEEFEVIETPEQIQAKTKNVSKKVTSKVKAQLDLRGMRYEEAELELDNYID
QALLANLIQITIVHGIGTGVIREMVQKKLQKHRHIKSYEYAPINAGGSGATIAILK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=51671 KW2_RS08025 WP_021037597.1 1698791..1701121(-) (mutS/mutS2) [Lactococcus cremoris subsp. cremoris KW2]
ATGAATAAAAAAATTCTCCAAATATTGGAATATGATAAAGTCAAAGAGCAGTTTATGAATGCTTTGACGACAGCGCAGGG
TCAGAAAGAATTATCTGATTTAGTCCCCTTGACCGATAAAGATAAGATTCAGCTCCTTTTTGATGAGGTTGCTGATTTTC
GCTTATTGACTCAAGAAAATGGTTTGTTAAATTTAGGGAAAACAAATGATTTAACTGAGATTCTGCGACGCTTGGAGCTT
GAAGCGAGTCTTTCAGGAAAAGAATTTGTTGAAATAAAAAAAGTGATTCAACTTGGAATCAATATTCAACGTTTTTTTGA
TGAAGCTGAAAACGTTGAAACACCATCACTAAATATTACTTTAGAAAAATTGGTTGATTTATCAGGGCTGATTAAGAAAT
TAGAAATCTTTGATAATGCCGGTAGTCTTTACGATAATGCAAGTCTGGAATTGATGCACATTCGTGCCTCTATCAAGAGT
CATCAGTCAGAAATTCGTAAAATTATGCAAGAAATGCTGACAAAAAATCTCTCATCTTTGAGTGAAAATGTCATCACTAT
TCGAAATGACCGTCAAGTTCTTCCTGTAAAAGCAGAAAATAAAAATAAAATTGCCGGAGTCGTTCATGATATGTCCGCTT
CTGGTCAAACGCTTTATATTGAACCGAATGCGGTAGTTTCACTTAATAATAAGCTTAATCAAAAACGAATTGAAGAACGA
CAAGAAATTACAAGAATTTATAGAGAACTTGCTGAAGAATTAAAACCTTATAGTTTTGATATTCGGCAAAATGCTTGGCT
GATTGGACATATTGACTTTGTTCGGGCAAAATATCTTTATTTGACAGCTAATAAGGCAAGCTTGCCTGCTTTAACACATG
ATAAAGATATTATCTTGTTTGCCGCTCGTCATCCTTTGATTGATGCAAAAATGGTTGTGGCAAATGATATTAAATTTGAC
AGAACACTCAATACAATTGTCATTACGGGGCCGAATACAGGTGGTAAAACTATTACCCTGAAAACAGTTGGTTTACTTAC
TATTTTAGCTCAATCAGGTTTGCCAATTTTAGCGGATGATGGCAGCCGTATTCATCTTTTTGATGACATTTTTGCTGATA
TTGGTGATGAACAATCCATTGAACAAAGTTTGTCAACTTTCTCAAGTCATATGACGAATATTGTACAAATTTTAGCTCAG
GCTGATGAAAATAGTTTGGTCTTGTTTGATGAACTTGGAGCAGGGACTGACCCGAAAGAAGGGGCAGCACTTGCGATTGC
CATTCTTGAAAATTTACGAAAACGAAATGTTAAAACAATGGCAAGTACCCACTATCCAGAGCTGAAAGCTTATGGTGTGG
AAACGCAGCAAGTGATCAATGCCAGTATGGAATTTAACATTGATAAAATGCAGCCAACTTATCATTTGCAACTTGGTGTG
CCAGGACGTTCAAATGCTTTAGAGATTTCTAGACGATTGGGCTTACCTGAAACAATTATCTCTGAGGCCAGCCAACAAAT
CTCTGAGAGCGAACATGATGTCAATCAAATGATTGAAAAGTTGGAAGAAAAAACGCGTGAAGTCATTGAAAGTTCAAGAA
ATATCAAAAAAATTGAACGAGAAAATCAAAGTTTACATAAAGATTTGACGAAAGTTTATAACCAAATTAACCGCGAACGT
GACTTTGAATTAGAAAAAGCCCAAAAAGAAGCTCAAGAAGTAGTTAAAAAAGCGAGTCTTGAGGCTCAAGAAATCTTGAA
AAATCTTAATGATAAAGCGGCATTAAAGCCCCATGAAATCATCGCTGCTAGAAAAGAACTTGAGGGCTTAGCGCCAACCA
TTGATTTTTCTAAAAACAAGGTTTTGAAAAAAGCCAAGGCACAAAGAGGACTTAAGCAAGGGGCTGAGGTCAATGTTACT
TCTTATGGTCAGCGCGGAAAATTGATTCGTTTAGAAAAAGATGGCCGTTGGACAGTCCAAATGGGTTCAATTACTACTCG
TTTAAGTGAAGAAGAGTTTGAAGTCATTGAGACTCCTGAACAAATTCAAGCAAAAACTAAAAATGTCAGCAAAAAAGTAA
CTTCTAAGGTTAAAGCACAGCTAGATTTACGTGGGATGCGTTATGAAGAAGCAGAACTGGAATTGGACAATTATATTGAT
CAGGCTTTACTTGCAAATCTAATTCAAATTACGATTGTTCATGGGATTGGAACAGGTGTCATTCGAGAAATGGTTCAGAA
AAAACTTCAAAAACATCGTCATATCAAATCTTATGAATATGCGCCAATCAATGCTGGAGGCTCTGGAGCAACCATTGCCA
TTTTGAAATAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(326-509)

Smr domain (Smr)

(701-776)

MutS2 and Smr-associated SH3 domain (MSSS)

(634-672)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

43.003

100

0.436

Multiple sequence alignment