Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   I6I31_RS00240 Genome accession   NZ_CP066042
Coordinates   40164..40880 (+) Length   238 a.a.
NCBI ID   WP_115312976.1    Uniprot ID   A0A380H0W7
Organism   Staphylococcus saccharolyticus strain FDAARGOS_1074     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 35164..45880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I31_RS00215 (I6I31_00215) - 36571..37355 (+) 785 Protein_43 carbon-nitrogen family hydrolase -
  I6I31_RS00220 (I6I31_00220) hld 37730..37810 (-) 81 WP_115312980.1 delta-hemolysin -
  I6I31_RS00225 (I6I31_00225) - 38123..38707 (+) 585 WP_115312979.1 accessory gene regulator AgrB -
  I6I31_RS00230 (I6I31_00230) - 38691..38831 (+) 141 WP_115312978.1 cyclic lactone autoinducer peptide AgrD -
  I6I31_RS00235 (I6I31_00235) - 38858..40147 (+) 1290 WP_115312977.1 quorum-sensing sensor histidine kinase AgrC -
  I6I31_RS00240 (I6I31_00240) agrA 40164..40880 (+) 717 WP_115312976.1 quorum-sensing response regulator AgrA Regulator
  I6I31_RS00245 (I6I31_00245) - 40999..42474 (-) 1476 WP_115312975.1 sucrose-6-phosphate hydrolase -
  I6I31_RS00250 (I6I31_00250) - 42740..43693 (-) 954 Protein_50 LacI family DNA-binding transcriptional regulator -
  I6I31_RS00255 (I6I31_00255) - 43829..45067 (-) 1239 Protein_51 ammonium transporter -
  I6I31_RS00260 (I6I31_00260) - 45242..45468 (-) 227 Protein_52 sulfurtransferase TusA family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.03 Da        Isoelectric Point: 6.3014

>NTDB_id=516687 I6I31_RS00240 WP_115312976.1 40164..40880(+) (agrA) [Staphylococcus saccharolyticus strain FDAARGOS_1074]
MKIFVCEDDPRQRENIVSIIKNYIMIEEKPMELTLATNDPYEVLKQSKEMNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNIDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLISHLDNRQIEFYGNLKELAQLDNRFFRCHNSFVVNRHNIESIDSKERIVYFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=516687 I6I31_RS00240 WP_115312976.1 40164..40880(+) (agrA) [Staphylococcus saccharolyticus strain FDAARGOS_1074]
ATGAAAATATTCGTTTGCGAAGATGATCCAAGACAAAGAGAGAACATTGTTTCAATTATAAAAAACTATATTATGATTGA
AGAAAAACCTATGGAATTGACTCTCGCAACTAATGATCCTTATGAGGTTCTAAAACAATCCAAAGAAATGAATGACATCG
GTTGTTATTTCCTTGATATTCAATTAGAAGCTGATATGAATGGTATTAAACTTGCCAGCGAAATTCGTAAACATGATCCT
GTAGGCAATATTATATTTGTGACAAGTCATAGTGAACTCACTTATTTAACGTTTGTATATAAAGTCGCTGCAATGGACTT
TATTTTTAAAGATGATCCATCAGAACTTAAAATGAGAATTATTGATTGTCTTGAAACAGCACATACACGTTTAAAATTAC
TATCTAAAGAAAGTAATATAGACACCATTGAGTTGAAACGTGGTAGCAATTCGGTATATGTACAATATGACGATATCATG
TTTTTTGAATCATCTACAAAGTCACATCGTCTGATTTCACATCTTGATAATCGTCAAATTGAGTTTTACGGAAATTTAAA
AGAATTGGCACAACTTGATAATCGCTTCTTTAGATGTCATAACAGCTTTGTAGTTAATAGACATAATATCGAGTCTATTG
ATTCTAAAGAACGTATCGTTTATTTTAAAAATGGAGAACATTGTTTCGCGTCCGTACGTAATGTTAAAAAAATTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380H0W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878