Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   I6H77_RS03990 Genome accession   NZ_CP066021
Coordinates   814971..816320 (-) Length   449 a.a.
NCBI ID   WP_000801576.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1020     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 809971..821320
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H77_RS03980 (I6H77_03980) - 810314..814039 (-) 3726 WP_000361223.1 phosphoribosylformylglycinamidine synthase -
  I6H77_RS03985 (I6H77_03985) purC 814096..814803 (-) 708 WP_000043288.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  I6H77_RS03990 (I6H77_03990) comB 814971..816320 (-) 1350 WP_000801576.1 competence pheromone export protein ComB Regulator
  I6H77_RS03995 (I6H77_03995) comA 816333..818486 (-) 2154 WP_000672141.1 peptide cleavage/export ABC transporter ComA Regulator
  I6H77_RS04000 (I6H77_04000) - 818921..819109 (-) 189 WP_000722235.1 hypothetical protein -
  I6H77_RS04005 (I6H77_04005) - 819119..819286 (-) 168 WP_000415691.1 bacteriocin -
  I6H77_RS04010 (I6H77_04010) - 819304..819492 (-) 189 WP_000180830.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I6H77_RS04015 (I6H77_04015) - 819933..820169 (-) 237 WP_000136451.1 acyl carrier protein -
  I6H77_RS04020 (I6H77_04020) plsX 820175..821167 (-) 993 WP_000717449.1 phosphate acyltransferase PlsX -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49932.77 Da        Isoelectric Point: 5.0481

>NTDB_id=516463 I6H77_RS03990 WP_000801576.1 814971..816320(-) (comB) [Streptococcus oralis strain FDAARGOS_1020]
MKPEFLESAEFYHRRYHNFSSRVILPMSLMLVFLFGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGDLLVEYQQGAEAVQAEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIEKGDQLDSQNAAYSFYQTYKNQAGDDSQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAYATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKIIASEDGVLH
LNPETSESTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEK
GNFFKIEAETSLTPEQAESLRYGSEGRLTLITGKKSYLRYYWDQFLNRE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=516463 I6H77_RS03990 WP_000801576.1 814971..816320(-) (comB) [Streptococcus oralis strain FDAARGOS_1020]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTACCATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCGCTTATGCTCGTGTTTCTGTTTGGATTTGCAGTCTTTGCTGAGAAAGAGATTAGTTTGTCTACTAGAGCTACTGTCG
AACCTAGTCGGATCATTGCCAACATCCAGTCGACTAGCAATCAACGGATTGTGGCAAATTATCTGGAAGAAAATAAACTG
GTCAAGCAGGGGGATTTACTCGTTGAGTACCAGCAGGGGGCGGAAGCTGTTCAAGCTGAAGCATACGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGTTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCGG
ATAAGTTTGGATATCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTTAGGAGCAATGTTTCTCAACAAAAT
GCCAGCATCTCTTCTCAAAATGCAGCCGCAAGTCAGAGTCAGGCTGAGATTGGCAACCTTATCAGCCAAACAGAGGATAA
AATCCGAGATTACAAAACAGCTAAGTCGGCGATTGAAAAAGGAGATCAACTGGATAGTCAAAATGCAGCCTACTCATTTT
ATCAGACTTATAAAAACCAAGCTGGAGATGATTCGCAAGCTAAATCGCAAGTTATTGCACAGGTGGATGCACAAATTGCC
CAGCTAGAGTCTAGTTTAGCTACTTATCGTGTGCAGTATGCGGGTTCTGGAGCTCAACAAGCCTACGCAACGGGACTGGA
TAGTCAACTGGAATCCCTCAAGTCTCAGCACCTAGTCAAAGTCGGCCAGGAATTAACCCTTTTGGATCAGAAAATTTTGG
AGGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTGCTGGACAAGGGGAAAATTATAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACCAGTGAATCTACGATGGTTGCAGAAGGAACTCTGCTAGCCCAGCTCTATCCATCCTTGGAAAAAGA
AGGCAAAACCAAACTCACAGCCTATCTCAGTTCAAAAGATGTTGCTAGAGTTAAGATTGGGGACTCTGTCCGTTATACTA
CGACTAATGATGCGAAGAATCAAATCTTCCTGGATTCTACGATTACAAGTATTGATGCGACAGCTACCAAGACTGAAAAG
GGCAATTTCTTTAAAATAGAGGCGGAGACCAGTCTGACTCCTGAACAGGCAGAAAGTCTTCGCTATGGTTCAGAAGGGCG
TTTGACGCTAATCACAGGGAAGAAAAGCTATTTGCGCTATTATTGGGATCAATTTTTGAACAGAGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

81.96

100

0.82
  comB Streptococcus pneumoniae Rx1

81.069

100

0.811
  comB Streptococcus pneumoniae D39

81.069

100

0.811
  comB Streptococcus pneumoniae R6

81.069

100

0.811
  comB Streptococcus pneumoniae TIGR4

80.624

100

0.806
  comB Streptococcus mitis NCTC 12261

79.955

100

0.8
  comB Streptococcus gordonii str. Challis substr. CH1

54.667

100

0.548