Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   I6H77_RS02920 Genome accession   NZ_CP066021
Coordinates   616728..617552 (-) Length   274 a.a.
NCBI ID   WP_000359002.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1020     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 611728..622552
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H77_RS02905 (I6H77_02905) amiA 612779..614758 (-) 1980 WP_000749706.1 peptide ABC transporter substrate-binding protein Regulator
  I6H77_RS02915 (I6H77_02915) - 615261..616592 (-) 1332 WP_000390016.1 hemolysin family protein -
  I6H77_RS02920 (I6H77_02920) endA 616728..617552 (-) 825 WP_000359002.1 DNA/RNA non-specific endonuclease Machinery gene
  I6H77_RS02925 (I6H77_02925) - 617593..617787 (-) 195 WP_000739701.1 DNA-directed RNA polymerase subunit beta -
  I6H77_RS02930 (I6H77_02930) murA 617774..619057 (-) 1284 WP_000411908.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  I6H77_RS02935 (I6H77_02935) - 619081..619311 (-) 231 WP_002874202.1 DUF1146 family protein -
  I6H77_RS02940 (I6H77_02940) sepM 619367..620404 (-) 1038 WP_000730772.1 SepM family pheromone-processing serine protease Regulator
  I6H77_RS02945 (I6H77_02945) coaD 620388..620876 (-) 489 WP_001280719.1 pantetheine-phosphate adenylyltransferase -
  I6H77_RS02950 (I6H77_02950) rsmD 620866..621405 (-) 540 WP_002874201.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  I6H77_RS02955 (I6H77_02955) asnA 621470..622462 (-) 993 WP_000747998.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 30070.70 Da        Isoelectric Point: 9.8219

>NTDB_id=516450 I6H77_RS02920 WP_000359002.1 616728..617552(-) (endA) [Streptococcus oralis strain FDAARGOS_1020]
MDKKTRQALIGLLLFLLLAAGSYYIKQMQSAPNNPRTKVNQKKQASEAPSQELAESVLTESIKNQIKGNLEWNGAGAFVV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKVLDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVTD

Nucleotide


Download         Length: 825 bp        

>NTDB_id=516450 I6H77_RS02920 WP_000359002.1 616728..617552(-) (endA) [Streptococcus oralis strain FDAARGOS_1020]
ATGGACAAAAAAACAAGACAAGCTCTGATAGGATTACTTCTATTCTTACTCTTGGCTGCTGGAAGCTACTACATCAAGCA
GATGCAGTCAGCACCAAATAACCCTAGAACCAAGGTTAATCAGAAAAAACAAGCTTCAGAAGCACCCAGTCAGGAGTTGG
CAGAAAGTGTCTTAACCGAGTCAATCAAAAACCAAATCAAGGGTAATCTCGAGTGGAATGGAGCAGGGGCCTTTGTTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCAAGCAAACCCTATGCGGATAATAAAACAAAGACAGTGGGAAAAGA
AACAGTTCCAACTGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAGAATCGTGAAGAGACTGGAAATGGCT
CAACCTCTTGGACGCCACCAGGATGGCATCAGGTTAAGAATCTAAAGGGAACCTACACACATGCAGTTGATAGAGGACAC
CTGCTGGGCTATGCCTTGATAGGTGGTTTGGATGGTTTTGATGCCTCTACTAGCAATCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCCAACCAGGCTCAGGCTGAAGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGTCTTGGACC
AAAATAAGAGAGTCCGTTATCGGGTGACGCTCCACTATGCGACAAATGAGGACTTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCAGATGGCGAATTGGAATTCAATGTCCTAATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCGAAC
AGGGCAAGTAACAGTGACAGATTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

88.645

99.635

0.883
  endA Streptococcus pneumoniae D39

88.645

99.635

0.883
  endA Streptococcus pneumoniae R6

88.645

99.635

0.883
  endA Streptococcus pneumoniae TIGR4

88.645

99.635

0.883