Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   I6I29_RS11120 Genome accession   NZ_CP065998
Coordinates   2260924..2262552 (+) Length   542 a.a.
NCBI ID   WP_001186596.1    Uniprot ID   -
Organism   Staphylococcus pseudintermedius strain FDAARGOS_1072     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2259557..2274363 2260924..2262552 within 0


Gene organization within MGE regions


Location: 2259557..2274363
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I29_RS11115 (I6I29_11115) ccrA 2259557..2260903 (+) 1347 WP_000816499.1 recombinase family protein Machinery gene
  I6I29_RS11120 (I6I29_11120) ccrB 2260924..2262552 (+) 1629 WP_001186596.1 recombinase family protein Machinery gene
  I6I29_RS11125 (I6I29_11125) - 2263023..2263373 (+) 351 WP_000171449.1 SAUGI family uracil-DNA glycosylase inhibitor -
  I6I29_RS11130 (I6I29_11130) - 2263458..2263769 (+) 312 WP_000833212.1 DUF960 family protein -
  I6I29_RS11135 (I6I29_11135) - 2263788..2264309 (+) 522 WP_000836008.1 DUF1643 domain-containing protein -
  I6I29_RS11140 (I6I29_11140) - 2264311..2264517 (+) 207 WP_001077283.1 hypothetical protein -
  I6I29_RS14200 - 2264615..2264875 (+) 261 Protein_2175 JAB domain-containing protein -
  I6I29_RS11150 (I6I29_11150) - 2264929..2265567 (-) 639 Protein_2176 sulfite exporter TauE/SafE family protein -
  I6I29_RS11155 (I6I29_11155) cstR 2265567..2265827 (-) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  I6I29_RS11160 (I6I29_11160) - 2265963..2267027 (+) 1065 WP_000438836.1 DsrE/DsrF/DrsH-like family protein -
  I6I29_RS11165 (I6I29_11165) cstB 2267060..2268394 (+) 1335 Protein_2179 persulfide dioxygenase-sulfurtransferase CstB -
  I6I29_RS11170 (I6I29_11170) - 2268508..2269617 (-) 1110 WP_025904162.1 ROK family transcriptional regulator -
  I6I29_RS11175 (I6I29_11175) psm-mec 2269976..2270044 (+) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  I6I29_RS11180 (I6I29_11180) mecI 2270129..2270500 (-) 372 WP_025904161.1 mecA-type methicillin resistance repressor MecI -
  I6I29_RS11185 (I6I29_11185) mecR1 2270500..2272257 (-) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  I6I29_RS11190 (I6I29_11190) mecA 2272354..2274363 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62274.15 Da        Isoelectric Point: 9.7334

>NTDB_id=516223 I6I29_RS11120 WP_001186596.1 2260924..2262552(+) (ccrB) [Staphylococcus pseudintermedius strain FDAARGOS_1072]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=516223 I6I29_RS11120 WP_001186596.1 2260924..2262552(+) (ccrB) [Staphylococcus pseudintermedius strain FDAARGOS_1072]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-156)

Recombinase (Recombinase)

(180-280)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

86.531

100

0.865